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Last updated 3 days ago

Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability

3 days ago

Nature Methods, Published online: 24 March 2025; doi:10.1038/s41592-025-02632-3This work presents an in...

Simultaneous single-cell DNA damage profiling and RNA sequencing by Paired-Damage-seq

3 days ago

Nature Methods, Published online: 24 March 2025; doi:10.1038/s41592-025-02634-1We developed Paired-Damage-seq to profile...

Connectivity of single neurons classifies cell subtypes in mouse brains

6 days ago

Nature Methods, Published online: 21 March 2025; doi:10.1038/s41592-025-02621-6This Resource presents a method...

Marrying mechanics with spatial transcriptomics

8 days ago

Nature Methods, Published online: 19 March 2025; doi:10.1038/s41592-024-02491-4A method infers tension from...

Comparing chromatin contact maps at scale: methods and insights

8 days ago

Nature Methods, Published online: 19 March 2025; doi:10.1038/s41592-025-02630-5This study presents a benchmarking...

A graph neural network that combines scRNA-seq and protein–protein interaction data

9 days ago

Nature Methods, Published online: 18 March 2025; doi:10.1038/s41592-025-02628-zWe introduce a dual-view graph...

A computational pipeline for spatial mechano-transcriptomics

10 days ago

Nature Methods, Published online: 17 March 2025; doi:10.1038/s41592-025-02618-1The authors present a computational...

Propensity score weighting

10 days ago

Nature Methods, Published online: 17 March 2025; doi:10.1038/s41592-025-02629-yThe needs of the many...

scNET: learning context-specific gene and cell embeddings by integrating single-cell gene expression data with protein–protein interactions

10 days ago

Nature Methods, Published online: 17 March 2025; doi:10.1038/s41592-025-02627-0scNET combines single-cell gene expression...

Human BioMolecular Atlas Program (HuBMAP): 3D Human Reference Atlas construction and usage

14 days ago

Nature Methods, Published online: 13 March 2025; doi:10.1038/s41592-024-02563-5This Resource describes data, code...

A systematic benchmark of Nanopore long-read RNA sequencing for transcript-level analysis in human cell lines

14 days ago

Nature Methods, Published online: 13 March 2025; doi:10.1038/s41592-025-02623-4This analysis provides a collection...

Feature selection methods affect the performance of scRNA-seq data integration and querying

14 days ago

Nature Methods, Published online: 13 March 2025; doi:10.1038/s41592-025-02624-3This Registered Report presents a...