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Last updated about 18 hours ago

Modeling cell fates across space and time

about 18 hours ago

Nature Methods, Published online: 10 November 2025; doi:10.1038/s41592-025-02884-zWe present STORIES, a computational...

A Minimum Information about a High Containment Laboratory Experiment (MIHCLE) reporting standard

about 21 hours ago

Nature Methods, Published online: 10 November 2025; doi:10.1038/s41592-025-02862-5Experiments with high-risk pathogens are...

Imaging the genome in motion

4 days ago

Nature Methods, Published online: 07 November 2025; doi:10.1038/s41592-025-02920-yTRACK-IT offers a live-cell 3D...

nELISA: a high-throughput, high-plex platform enables quantitative profiling of the inflammatory secretome

4 days ago

Nature Methods, Published online: 07 November 2025; doi:10.1038/s41592-025-02861-6nELISA miniaturizes the sandwich immunoassay...

Monod: model-based discovery and integration through fitting stochastic transcriptional dynamics to single-cell sequencing data

4 days ago

Nature Methods, Published online: 07 November 2025; doi:10.1038/s41592-025-02832-xMonod fits biophysically motivated models...

Genome-wide bacterial genetic interaction mining by dual Tn-seq

4 days ago

Nature Methods, Published online: 07 November 2025; doi:10.1038/s41592-025-02921-xGenome-wide bacterial genetic interaction mining...

Poison frogs

4 days ago

Nature Methods, Published online: 07 November 2025; doi:10.1038/s41592-025-02885-yEndowed with formidable chemical defenses...

Scaling up sequence searching

4 days ago

Nature Methods, Published online: 07 November 2025; doi:10.1038/s41592-025-02922-wScaling up sequence searching

What witnessing neurosurgery taught me about modeling the brain

5 days ago

Nature Methods, Published online: 06 November 2025; doi:10.1038/s41592-025-02898-7As a computational neuroscientist, I...

A portable poison exon for small-molecule control of mammalian gene expression

8 days ago

Nature Methods, Published online: 03 November 2025; doi:10.1038/s41592-025-02860-7This work introduces Cyclone, an...

ESPRESSO: spatiotemporal omics based on organelle phenotyping

8 days ago

Nature Methods, Published online: 03 November 2025; doi:10.1038/s41592-025-02863-4ESPRESSO leverages functional information obtained...

STORIES: learning cell fate landscapes from spatial transcriptomics using optimal transport

8 days ago

Nature Methods, Published online: 03 November 2025; doi:10.1038/s41592-025-02855-4By learning a differentiation potential...