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Last updated about 5 hours ago
Sharing data from the Human Tumor Atlas Network through standards, infrastructure and community engagement
about 5 hours ago
Nature Methods, Published online: 31 March 2025; doi:10.1038/s41592-025-02643-0This Perspective outlines the datasets...
Uncalled4 improves nanopore DNA and RNA modification detection via fast and accurate signal alignment
3 days ago
Nature Methods, Published online: 28 March 2025; doi:10.1038/s41592-025-02631-4Uncalled4 is a toolkit for...
Denoising Search doubles the number of metabolite and exposome annotations in human plasma using an Orbitrap Astral mass spectrometer
3 days ago
Nature Methods, Published online: 28 March 2025; doi:10.1038/s41592-025-02646-xSpectral Denoising removes chemical and...
Atomic context-conditioned protein sequence design using LigandMPNN
3 days ago
Nature Methods, Published online: 28 March 2025; doi:10.1038/s41592-025-02626-1LigandMPNN is a deep-learning-based protein...
Enabling global image data sharing in the life sciences
3 days ago
Nature Methods, Published online: 28 March 2025; doi:10.1038/s41592-024-02585-zThis Perspective provides a roadmap...
Single-cell parallel analysis of DNA damage and transcriptome reveals selective genome vulnerability
7 days ago
Nature Methods, Published online: 24 March 2025; doi:10.1038/s41592-025-02632-3This work presents an in...
Simultaneous single-cell DNA damage profiling and RNA sequencing by Paired-Damage-seq
7 days ago
Nature Methods, Published online: 24 March 2025; doi:10.1038/s41592-025-02634-1We developed Paired-Damage-seq to profile...
Connectivity of single neurons classifies cell subtypes in mouse brains
10 days ago
Nature Methods, Published online: 21 March 2025; doi:10.1038/s41592-025-02621-6This Resource presents a method...
Marrying mechanics with spatial transcriptomics
12 days ago
Nature Methods, Published online: 19 March 2025; doi:10.1038/s41592-024-02491-4A method infers tension from...
Comparing chromatin contact maps at scale: methods and insights
12 days ago
Nature Methods, Published online: 19 March 2025; doi:10.1038/s41592-025-02630-5This study presents a benchmarking...
A graph neural network that combines scRNA-seq and protein–protein interaction data
14 days ago
Nature Methods, Published online: 18 March 2025; doi:10.1038/s41592-025-02628-zWe introduce a dual-view graph...
A computational pipeline for spatial mechano-transcriptomics
14 days ago
Nature Methods, Published online: 17 March 2025; doi:10.1038/s41592-025-02618-1The authors present a computational...