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Last updated about 1 hour ago
A fully automated benchmarking suite to compare macromolecular complexes
about 1 hour ago
Nature Methods, Published online: 22 December 2025; doi:10.1038/s41592-025-02973-zThis study advances methods for...
Modeling developmental morpho-dynamics at single-cell resolution
about 1 hour ago
Nature Methods, Published online: 22 December 2025; doi:10.1038/s41592-025-02989-5We present MultiCell, a geometric...
Tracking cell ancestry and spatial gene expression with high resolution
about 1 hour ago
Nature Methods, Published online: 22 December 2025; doi:10.1038/s41592-025-02964-0We developed SpaceBar, a method...
Cell context-dependent in silico organelle localization in label-free microscopy images
3 days ago
Nature Methods, Published online: 19 December 2025; doi:10.1038/s41592-025-02960-4CELTIC is a context-dependent deep...
Methods to analyze cell migration data: fundamentals and practical guidelines
4 days ago
Nature Methods, Published online: 18 December 2025; doi:10.1038/s41592-025-02935-5This Review describes the principles...
Selecting the optimal cell migration assay: fundamentals and practical guidelines
4 days ago
Nature Methods, Published online: 18 December 2025; doi:10.1038/s41592-025-02890-1This Review introduces ten cell...
SpaceBar enables single-cell-resolution clone tracing with imaging-based spatial transcriptomics
4 days ago
Nature Methods, Published online: 18 December 2025; doi:10.1038/s41592-025-02968-wSpaceBar is a cellular barcoding...
Inferring cancer type-specific patterns of metastatic spread using Metient
5 days ago
Nature Methods, Published online: 17 December 2025; doi:10.1038/s41592-025-02924-8Metient is a statistical framework...
Orthogonal RNA-regulated destabilization domains for three-color RNA imaging with minimal RNA perturbation
5 days ago
Nature Methods, Published online: 17 December 2025; doi:10.1038/s41592-025-02905-xThis work presents two distinct...
High-parameter spatial multi-omics through histology-anchored integration
5 days ago
Nature Methods, Published online: 17 December 2025; doi:10.1038/s41592-025-02926-6The SpatialEx(+) framework uses histology...
Targeted RNA-binding protein degradation to improve mRNA live imaging in animal cells
5 days ago
Nature Methods, Published online: 17 December 2025; doi:10.1038/s41592-025-02869-yThe gold standard system for...
Dissecting how morphogens shape cell fates in human neural organoids
6 days ago
Nature Methods, Published online: 16 December 2025; doi:10.1038/s41592-025-02959-xWe systematically mapped how morphogen...