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Last updated 3 days ago
A tale of tumors
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02838-5Recent technological advances for studying...
MIFA: Metadata, Incentives, Formats and Accessibility guidelines to improve the reuse of AI datasets for bioimage analysis
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02835-8This Perspective discusses challenges associated...
Spatial gene expression at single-cell resolution from histology using deep learning with GHIST
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02795-zGHIST is a deep learning-based...
De novo discovery of conserved gene clusters in microbial genomes with Spacedust
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02816-xThis work presents Spacedust, a...
Scaling up spatial transcriptomics for large-sized tissues: uncovering cellular-level tissue architecture beyond conventional platforms with iSCALE
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02770-8iSCALE leverages histology and spatial...
MSnLib: efficient generation of open multi-stage fragmentation mass spectral libraries
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02813-0MSnLib is a large-scale, open...
Cancer subclone detection based on DNA copy number in single-cell and spatial omic sequencing data
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02773-5Clonalscope is a method for...
Integrating diverse experimental information to assist protein complex structure prediction by GRASP
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02820-1GRASP is a protein complex...
Bridging histology and spatial gene expression across scales
3 days ago
Nature Methods, Published online: 15 September 2025; doi:10.1038/s41592-025-02806-zTwo deep-learning frameworks — GHIST...
Coupling CRISPR scanning with targeted chromatin accessibility profiling using a double-stranded DNA deaminase
7 days ago
Nature Methods, Published online: 11 September 2025; doi:10.1038/s41592-025-02811-2This paper presents TDAC-seq, a...
Biophysics-based protein language models for protein engineering
7 days ago
Nature Methods, Published online: 11 September 2025; doi:10.1038/s41592-025-02776-2Mutational effect transfer learning (METL)...
Joint profiling of chromatin accessibility and CRISPR edits via double-stranded DNA deaminases
7 days ago
Nature Methods, Published online: 11 September 2025; doi:10.1038/s41592-025-02812-1Targeted deaminase-accessible chromatin sequencing (TDAC-seq)...