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Last updated 3 days ago

PHLOWER leverages single-cell multimodal data to infer complex, multi-branching cell differentiation trajectories

3 days ago

Nature Methods, Published online: 23 October 2025; doi:10.1038/s41592-025-02870-5PHLOWER leverages single-cell multimodal data...

The Hodge Laplacian advances inference of single-cell trajectories

3 days ago

Nature Methods, Published online: 23 October 2025; doi:10.1038/s41592-025-02858-1A recently proposed Hodge Laplacian...

scooby: modeling multimodal genomic profiles from DNA sequence at single-cell resolution

4 days ago

Nature Methods, Published online: 22 October 2025; doi:10.1038/s41592-025-02854-5scooby achieves DNA sequence-based single-cell...

CELLECT: contrastive embedding learning for large-scale efficient cell tracking

6 days ago

Nature Methods, Published online: 20 October 2025; doi:10.1038/s41592-025-02886-xCELLECT learns contrastive embeddings to...

gReLU: a comprehensive framework for DNA sequence modeling and design

11 days ago

Nature Methods, Published online: 15 October 2025; doi:10.1038/s41592-025-02868-zgReLU advances deep-learning-based modeling and...

Deep generative modeling of sample-level heterogeneity in single-cell genomics

13 days ago

Nature Methods, Published online: 13 October 2025; doi:10.1038/s41592-025-02808-xMrVI, based on deep generative...

Multitask benchmarking of single-cell multimodal omics integration methods

13 days ago

Nature Methods, Published online: 13 October 2025; doi:10.1038/s41592-025-02856-3This Registered Report compares computational...

Deciphering single-cell epigenomic language with a foundation model

15 days ago

Nature Methods, Published online: 10 October 2025; doi:10.1038/s41592-025-02851-8EpiAgent, a transformer-based foundation model...

Mouse lemurs

16 days ago

Nature Methods, Published online: 09 October 2025; doi:10.1038/s41592-025-02852-7Studying the gray mouse lemur...

What’s new at Nature Methods

16 days ago

Nature Methods, Published online: 09 October 2025; doi:10.1038/s41592-025-02883-0Team news, editorial projects and...

Enhancing prime editing via AI-guided binder design

16 days ago

Nature Methods, Published online: 09 October 2025; doi:10.1038/s41592-025-02872-3AI-designed binders can enhance prime...

Ionic liquids clear tissue without distortion

16 days ago

Nature Methods, Published online: 09 October 2025; doi:10.1038/s41592-025-02873-2Ionic liquids clear tissue without...