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Last updated 4 days ago

Reference genome choice compromises population genetic analyses

4 days ago

Using a species-specific reference genome significantly improves the accuracy of population genetic...

A brain center that controls consummatory responses

4 days ago

The BNST brain region integrates a broad range of external and internal...

Distinct circuit motifs evaluate opposing innate values of odors

4 days ago

Innate hedonic values of odors are computed in the Drosophila higher olfactory...

Time-resolved reprogramming of single somatic cells into totipotent states during plant regeneration

4 days ago

In Arabidopsis, transcriptional factors LEC2 and SPCH enhance local auxin biosynthesis, establishing...

Time-resolved fluorescent proteins expand fluorescent microscopy in temporal and spectral domains

4 days ago

A family of rationally designed time-resolved fluorescent proteins with controllable lifetimes across...

Nutrient competition predicts gut microbiome restructuring under drug perturbations

4 days ago

Systematic profiling of 707 drugs on their impact on stool-derived microbial communities...

Sequencing-free whole-genome spatial transcriptomics at single-molecule resolution

4 days ago

RAEFISH delivers whole-transcriptome (>20,000 genes) imaging at single-molecule resolution in cells and...

Pan-modification profiling facilitates a cross-evolutionary dissection of the thermoregulated ribosomal epitranscriptome

4 days ago

Pan-Mod-seq enables systematic, multi-modification mapping of rRNA across life. Applying it to...

Choreography of rapid actin filament disassembly by coronin, cofilin, and AIP1

4 days ago

The rapid turnover of actin filament networks drives eukaryotic cell migration and...

Single-cell nascent transcription reveals sparse genome usage and plasticity

4 days ago

scFLUENT-seq is a single-cell method that sensitively captures nascent nuclear transcriptomes to...

Unveiling conformation-selective regulation of the norepinephrine transporter

4 days ago

The inward-open-state-specific allosteric site in NET was structurally characterized, enabling the rational...