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Last updated 9 days ago

Molecular grammars of predicted intrinsically disordered regions that span the human proteome

9 days ago

Grammars inferred using NARDINI+ (GIN) is a resource that uncovers molecular grammars...

Thermodynamic principles link in vitro transcription factor affinities to single-molecule chromatin states in cells

9 days ago

In vitro-derived insights into features that drive transcription factor binding to DNA...

IL-1R1-positive dorsal raphe neurons drive self-imposed social withdrawal in sickness

9 days ago

During sickness, animals exhibit prolonged social withdrawal, a response that may limit...

HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

9 days ago

Melanoma cells escape immune surveillance by releasing MHC-antigen-loaded large EVs, known as...

A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

9 days ago

A fin-like structural loop in GPX4 is critical for anchoring the enzyme...

Stress-induced sympathetic hyperactivation drives hair follicle necrosis to trigger autoimmunity

9 days ago

Acute stress causes immediate hair follicle necrosis and hair loss via sympathetic...

Gut microbiota promotes immune tolerance at the maternal-fetal interface

9 days ago

Microbiota-dependent tryptophan-derived indole deficiency is linked to mouse fetal resorption and human...

Inhibition of heme biosynthesis triggers cuproptosis in acute myeloid leukemia

9 days ago

Reduced levels of the essential metabolite heme are a common feature of...

Single-cell susceptibility to viral infection is driven by variable cell states

9 days ago

Not all cells that can be infected by a virus become infected...

Renal PIEZO2 is an essential regulator of renin

9 days ago

The force-sensing ion channel PIEZO2 is an essential regulator of the renin-angiotensin-aldosterone...

Membrane potential mediates the cellular response to mechanical pressure

9 days ago

Cells in tissues need to know when to start growing and when...

Biomaterial-minimalistic photoactivated bioprinting of cell-dense tissues

9 days ago

We developed a bioprinting strategy that turns living cells into cell-only bioinks...