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Last updated 4 days ago
Microbiome metabolism of dietary phytochemicals controls the anticancer activity of PI3K inhibitors
4 days ago
Diet can impact anticancer drug activity. A classic example in rodents is...
A single-cell atlas reveals immune heterogeneity in anti-PD-1-treated non-small cell lung cancer
4 days ago
scRNA/TCR-seq analysis of 234 anti-PD-1-treated tumors identified immune heterogeneity associated with short-term...
Red blood cells undergo lytic programmed cell death involving NLRP3
4 days ago
Complement exposure induces programmed cell death of red blood cells due to...
A suite of enhancer AAVs and transgenic mouse lines for genetic access to cortical cell types
4 days ago
Ben-Simon et al. present a comprehensive toolkit of transgenic lines and enhancer...
Molecular basis for shifted receptor recognition by an encephalitic arbovirus
4 days ago
Cryo-EM structures and mutational analyses reveal western equine encephalitis virus E2-E1 glycoprotein...
Optimizing stem cell infusion timing in the prevention of acute graft-versus-host disease
4 days ago
Adjusting the timing of stem cell infusion can reduce the incidence and...
Long-term histone lactylation connects metabolic and epigenetic rewiring in innate immune memory
4 days ago
Lactate production in innate immune cells can regulate both acute and long-term...
DNA binding and mitotic phosphorylation protect polyglutamine proteins from assembly formation
4 days ago
DNA binding and phosphorylation protect FOXP2, a transcription factor with the longest...
Extracellular respiration is a latent energy metabolism in Escherichia coli
4 days ago
Escherichia coli can anaerobically respire and grow on an anode as the...
An Arabidopsis single-nucleus atlas decodes leaf senescence and nutrient allocation
4 days ago
A comprehensive single-nucleus transcriptomic atlas of Arabidopsis across multiple tissues enables the...
Structure and infection dynamics of mycobacteriophage Bxb1
4 days ago
Cryo-EM and cryo-ET reveal the structural details and conformational dynamics of mycobacteriophage...
Structural basis for plasticity in receptor engagement by an encephalitic alphavirus
4 days ago
Cryoelectron microscopy and structure-guided mutagenesis experiments show that Western equine encephalitis virus...