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Last updated 5 days ago
A unified cell atlas of vascular plants reveals cell-type foundational genes and accelerates gene discovery
5 days ago
A cross-species single-cell atlas highlights a core subset of cell-type foundational genes...
Tumors hijack macrophages for iron supply to promote bone metastasis and anemia
5 days ago
Tumor cells mimic erythroblasts by hijacking a specialized macrophage population for iron...
Coalescing single-cell genomes and transcriptomes to decode breast cancer progression
5 days ago
wellDR-seq allows single-cell whole-genome and transcriptome co-profiling at scale, enabling dissections of...
Glycan shielding enables TCR-sufficient allogeneic CAR-T therapy
5 days ago
SPPL3 deletion modifies glycosylation on primary T cells, reducing allogeneic immune responses...
Functional RNA splitting drove the evolutionary emergence of type V CRISPR-Cas systems from transposons
5 days ago
Identification of TranC systems reveals evolutionary intermediates bridging from transposon-encoded TnpBs and...
Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection
5 days ago
Since 2022, several strains of the monkeypox virus adapted to human-to-human transmission...
RNA Pol II inhibition activates cell death independently from the loss of transcription
5 days ago
When RNA polymerase II (RNA Pol II) is inhibited, the inhibition is...
Structurally conserved human anti-A35 antibodies protect mice and macaques from mpox virus infection
5 days ago
Administration of human monoclonal antibodies against the MPXV A35 protein mitigate the...
Human monoclonal antibodies targeting A35 protect from death caused by mpox
5 days ago
Three potent mAbs against the conserved MPXV A35 protein block viral spread...
IL-25-induced memory type 2 innate lymphoid cells enforce mucosal immunity
5 days ago
IL-25 treatment induces persistent adaptation of the small intestine, which is maintained...
Transient gene melting governs the timing of oligodendrocyte maturation
5 days ago
Oligodendrocyte maturation is governed by an SOX6-dependent gene-melted chromatin state at multiple...
Multiscale proteomic modeling reveals protein networks driving Alzheimer’s disease pathogenesis
5 days ago
Multiscale proteomic network modeling of Alzheimer's disease integrates large-scale proteomic and genetic...