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Last updated about 14 hours ago

Bacteriophage genome-wide transposon mutagenesis

about 14 hours ago

A technique enabling phage transposon mutagenesis and sequencing reveals previously unknown non-essential...

Multimodal imaging of gene expression, morphology, and activity of the same neuron

about 14 hours ago

This study establishes an imaging-based multimodal characterization (IMC) platform to link in...

Map of spiking activity underlying change detection in the mouse visual system

about 14 hours ago

Large-scale Neuropixels recordings across the mouse visual system during an image-change detection...

Decoding the spatiotemporal development of human meninges

about 14 hours ago

A spatiotemporal atlas of the human meninges during early-to-mid gestation identifies asynchronous...

Physiological brain clearance architecture revealed by neuronal protein tracing

about 14 hours ago

Neuronal protein tracing, unlike CSF tracers, reveals that brain clearance follows a...

TPPP/p25 amyloid seeding activity as a specific biomarker for multiple system atrophy

about 14 hours ago

Characterization of TPPP/p25 amyloid aggregation enables the development of a seed amplification...

Arc mediates intercellular tau transmission via extracellular vesicles

about 14 hours ago

Tau pathology spreads cell to cell in Alzheimer’s disease, but the molecular...

Two distinct causes contribute to the low efficiency of human pre-implantation development

about 14 hours ago

Live imaging covering the entire human pre-implantation development reveals that the second...

Continuous modeling of primate embryogenesis from totipotency to early organogenesis

about 14 hours ago

A primate embryoid system is established from cynomolgus totipotent blastomere-like cells. This...

Harnessing citizen science to contextualize adaptation mechanism discovery

about 14 hours ago

Juxtaposing citizen science in situ observations and designed ex situ experiments through...

A spliceosome-independent eukaryote generated by complete intron removal

about 14 hours ago

Elimination of all spliceosomal introns reveals a spliceosome-independent eukaryote.

mRNA 3′ UTRs chaperone intrinsically disordered regions to control protein activity

about 14 hours ago

Highly conserved mRNA 3′ UTRs act as co-translational chaperones for intrinsically disordered...