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Last updated 14 days ago
Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy
14 days ago
The Cancer Immunology Data Engine, integrating 90 immuno-oncology omics datasets, identifies genes...
Senescence-resistant human mesenchymal progenitor cells counter aging in primates
14 days ago
Genetically engineered senescence-resistant human mesenchymal progenitor cells can reduce aging markers and...
Neuroendocrine cells orchestrate regeneration through Desert hedgehog signaling
14 days ago
Upon chemical or viral injury of airway or pancreatic islets, Desert hedgehog...
Bacteriophages inhibit and evade cGAS-like immune function in bacteria
14 days ago
(Cell 186, 864–876.e1–e11; February 16, 2023)
STAMP: Single-cell transcriptomics analysis and multimodal profiling through imaging
14 days ago
Single-cell transcriptomics analysis and multimodal profiling (STAMP) by imaging enables single-cell analysis...
Functional assessment of all ATM SNVs using prime editing and deep learning
14 days ago
Prime editing combined with machine learning-based evaluation of all 27,513 possible coding...
Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling
14 days ago
By designing synthetic toolkits for contact-based signaling (MARS) and cell-cell adhesion (SATURN)...
Single-cell multiregion epigenomic rewiring in Alzheimer’s disease progression and cognitive resilience
14 days ago
A single-cell epigenomic and transcriptomic atlas across six brain regions in Alzheimer’s...
An alternate receptor for adeno-associated viruses
14 days ago
Dhungel et al. report an alternate receptor for AAV (AAVR2, carboxypeptidase D)...
Neuroendocrine circuit for sleep-dependent growth hormone release
14 days ago
The increase in growth hormone release during sleep is driven by sleep-wake-dependent...
Optogenetics-enabled discovery of integrated stress response modulators
14 days ago
An optogenetics-enabled drug screening platform facilitates targeting of the integrated stress response...
Brain endothelial gap junction coupling enables rapid vasodilation propagation during neurovascular coupling
14 days ago
Vasodilatory signals are rapidly communicated across long distances by endothelial-endothelial gap junctions...