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Last updated 7 days ago
Multiple independent acquisitions of ACE2 usage in MERS-related coronaviruses
7 days ago
Two coronaviruses related to MERS-CoV, which infect European Pipistrellus bats, have been...
SnapShot: Human sperm-egg interface proteins
7 days ago
Human fertilization is a complex, highly regulated process that involves intricate molecular...
Molecular basis of convergent evolution of ACE2 receptor utilization among HKU5 coronaviruses
7 days ago
The family of coronaviruses known as merbecoviruses has generally been thought to...
Bat-infecting merbecovirus HKU5-CoV lineage 2 can use human ACE2 as a cell entry receptor
7 days ago
Coronaviruses of the merbecovirus family have been thought to enter cells by...
Neutrophil-derived vesicles control complement activation to facilitate inflammation resolution
7 days ago
Short-lived neutrophils are typically known for their pro-inflammatory role in pathogen clearance...
Extracellular vesicles from the lung pro-thrombotic niche drive cancer-associated thrombosis and metastasis via integrin beta 2
7 days ago
Cancer-associated thrombosis is a leading cause of mortality. Lucotti et al. uncover...
Identification, structure, and agonist design of an androgen membrane receptor
7 days ago
GPR133 is identified as a membrane receptor for the androgen subtype 5α-DHT...
Structure-guided discovery of viral proteins that inhibit host immunity
7 days ago
Large-scale, structure-guided computational pipeline sifts through millions of phage proteins to identify...
Mammary intraepithelial lymphocytes promote lactogenesis and offspring fitness
7 days ago
Mammary intraepithelial lymphocytes enhance mammary gland differentiation during pregnancy, thereby promoting offspring...
ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
7 days ago
ArfGAP2 is a dual regulator of STING signaling and proton efflux in...
HypoxyStat, a small-molecule form of hypoxia therapy that increases oxygen-hemoglobin affinity
7 days ago
A small molecule that increases oxygen-hemoglobin affinity was shown to prevent and...
Resolving the three-dimensional interactome of human accelerated regions during human and chimpanzee neurodevelopment
7 days ago
Human accelerated regions (HARs) have been implicated in human brain evolution with...