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Last updated 8 days ago

Nutrient-regulated control of lysosome function by signaling lipid conversion

8 days ago

(Cell 186, 5328–5346.e1–e12; November 22, 2023)

Crop root bacterial and viral genomes reveal unexplored species and microbiome patterns

8 days ago

Comprehensive bacterial and viral genome collections from crop roots uncover a large...

Genetically encoded reporters of actin filament organization in living cells and tissues

8 days ago

Tailoring genetic fusions of widely used actin localization reporters by constraining the...

Mechanism of DNA capture by the MukBEF SMC complex and its inhibition by a viral DNA mimic

8 days ago

Biochemical and structural analyses elucidate the mechanism of unidirectional DNA entrapment by...

Conserved genetic basis for microbial colonization of the gut

8 days ago

Tree-of-life scale genotype-habitat association reveals conserved gene modules across thousands of gut...

A chemical radar allows bacteria to detect and kill predators

8 days ago

Pseudomonas syringae can detect and kill microbial predators via a chemical radar...

Microtubules in Asgard archaea

8 days ago

Discovery of heterodimeric, microtubule-forming tubulins in Asgard archaea, the closest known relatives...

Functional and antigenic landscape of the Nipah virus receptor-binding protein

8 days ago

Nipah virus is a zoonotic virus that spills over to humans and...

Global analysis of protein turnover dynamics in single cells

8 days ago

The SC-pSILAC method enables single-cell measurement of both protein abundance and turnover...

Engineering TCR-controlled fuzzy logic into CAR T cells enhances therapeutic specificity

8 days ago

Robot-assisted analysis and theoretical modeling of TCR/CAR crosstalk enable the design of...

Microbiota-derived bile acids antagonize the host androgen receptor and drive anti-tumor immunity

8 days ago

Functional characterization of microbiota bile acid hydroxysteroid dehydrogenases identifies microbiota-derived bile acids...

Ligand-induced ubiquitination unleashes LAG3 immune checkpoint function by hindering membrane sequestration of signaling motifs

8 days ago

This study uncovers the molecular mechanism of LAG3 activation upon ligand engagement...