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Last updated 4 days ago

E3 ligase c-Cbl regulates intestinal inflammation through suppressing fungi-induced noncanonical NF-{kappa}B activation

4 days ago

Intestinal fungi are critical for modulating host immune homeostasis and underlying mechanisms...

Macrophage miR-210 induction and metabolic reprogramming in response to pathogen interaction boost life-threatening inflammation

4 days ago

Unbalanced immune responses to pathogens can be life-threatening although the underlying regulatory...

Persistent spectral-based machine learning (PerSpect ML) for protein-ligand binding affinity prediction

4 days ago

Molecular descriptors are essential to not only quantitative structure-activity relationship (QSAR) models...

A diverse member of the fungal Avr4 effector family interacts with de-esterified pectin in plant cell walls to disrupt their integrity

4 days ago

Effectors are small, secreted proteins that promote pathogen virulence. Although key to...

A distinct parabrachial-to-lateral hypothalamus circuit for motivational suppression of feeding by nociception

4 days ago

The motivation to eat is not only shaped by nutrition but also...

Combinatorial screen of dynamic mechanical stimuli for predictive control of MSC mechano-responsiveness

4 days ago

Mechanobiological-based control of mesenchymal stromal cells (MSCs) to facilitate engineering and regeneration...

Alternative glycosylation controls endoplasmic reticulum dynamics and tubular extension in mammalian cells

4 days ago

The endoplasmic reticulum (ER) is a central eukaryotic organelle with a tubular...

Programmable Bloch polaritons in graphene

4 days ago

Efficient control of photons is enabled by hybridizing light with matter. The...

Tissue-like skin-device interface for wearable bioelectronics by using ultrasoft, mass-permeable, and low-impedance hydrogels

4 days ago

Hydrogels consist of a cross-linked porous polymer network and water molecules occupying...

Structural insights into integrin {alpha}5{beta}1 opening by fibronectin ligand

4 days ago

Integrin α5β1 is a major fibronectin receptor critical for cell migration. Upon...

The impact of relaxing interventions on human contact patterns and SARS-CoV-2 transmission in China

4 days ago

Nonpharmaceutical interventions to control SARS-CoV-2 spread have been implemented with different intensity...

Engendering persistent organic room temperature phosphorescence by trace ingredient incorporation

4 days ago

Pure organic persistent room temperature phosphorescence (RTP) has shown great potential in...