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A near-complete map of human cytosolic degrons and their relevance for disease | Science Advances

1 day ago

Abstract Degrons are short protein segments that direct proteins for degradation via...

Antigen-specific TH17 cells offset the age-related decline in durable T cell immunity | Science Advances

1 day ago

Abstract Older adults are susceptible to infections in part due to waning...

Privacy-preserving data analysis using a memristor chip with colocated authentication and processing | Science Advances

1 day ago

Abstract Privacy-preserving data analysis is essential in health care applications to safeguard...

RTX-family toxin EhxA drives morphological remodeling and thrombogenesis in RBCs during enterohemorrhagic Escherichia coli infection | Science Advances

1 day ago

Abstract Enterohemorrhagic Escherichia coli (EHEC) causes thrombotic microangiopathy, yet the red blood...

Three-dimensional printing of nanomaterials-based electronics with a metamaterial-inspired near-field electromagnetic structure | Science Advances

1 day ago

Abstract Three-dimensional (3D) printing can create freeform architectures and electronics with unprecedented...

Expansive spatial pattern of Aβ deposition in patients with cerebral amyloid angiopathy: A three-dimensional surface-to-depth analysis | Science Advances

1 day ago

Abstract Cerebral amyloid angiopathy (CAA) is a neurodegenerative condition characterized by amyloid-β...

Divergent stem cell mechanisms govern the primary body axis and appendage regeneration in the axolotl | Science Advances

1 day ago

Abstract Exploring the fundamental mechanisms of organ regeneration is crucial for advancing...

Competitive-binding buried interlayer for year-round reproducible perovskite solar cells | Science Advances

1 day ago

Abstract Homogenizing the upper surface through posttreatment has made great progress in...

Resolving emergent transient oscillations in gene circuits with a growth-coupled model | Science Advances

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Abstract Synthetic gene circuits often behave unpredictably in batch cultures, where shifting...

Extracellular vesicles mediate stem cell signaling and systemic RNAi in planarians | Science Advances

1 day ago

Abstract Planarian flatworms are known for their remarkable regenerative capacity; however, the...

Climate, ecological dynamics, and the seasonal distribution of birds in mountains | Science Advances

1 day ago

Abstract Biodiversity is unevenly distributed along elevational gradients. The predominant hypothesis is...

Critical quantum metrology robust against dissipation and nonadiabaticity | Science Advances

1 day ago

Abstract Critical systems near quantum phase transitions were predicted to be useful...