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Glycerol-mediated nose-to-brain codelivery of anti–IL-17 and anti-CD73 antibodies enhances immunotherapy for melanoma brain metastases | Science Advances
1 day ago
Abstract Immune checkpoint inhibitors show promise in the treatment of melanoma brain...
High mannose content of mesenchymal glioblastoma correlates with hydroxyl proton transfer–weighted (HPTw) MRI as noninvasive biomarker of tumor aggressiveness | Science Advances
1 day ago
Abstract Glioblastoma (GBM) contains mesenchymal cancer stem cells that drive tumor aggressiveness...
Mechanical pulling force and alternating current comodulation electrohydrodynamic printing | Science Advances
1 day ago
Abstract To achieve precise printing using high-viscosity paste on insulating substrates, we...
Acidic-alkaline tandem system for durable CO2-CO-C2+ | Science Advances
1 day ago
Abstract Tandem carbon dioxide reduction reaction (CO 2 RR) to multicarbon products...
Pulsed volcanic sulfur emissions linked to the end-Triassic terrestrial crisis | Science Advances
1 day ago
Abstract The end-Triassic mass extinction (ETE) was triggered by Central Atlantic Magmatic...
m6A RNA modification guides alternative polyadenylation to maintain T cell quiescence | Science Advances
1 day ago
Abstract N 6 -Methyladenosine (m 6 A) is primarily enriched in the...
Magnetic medical microrobots with memory-capable genetic circuits | Science Advances
1 day ago
Abstract Autonomous microrobots can reach hard-to-access regions in the human body for...
A thyroid hormone–mediated opsin switch initiates metamorphosis in a proto-vertebrate | Science Advances
1 day ago
Abstract Thyroid hormones (THs) initiate metamorphosis in vertebrates, although the evolutionary origins...
A pioneering plastic particle footprint concept for addressing the challenges posed by plastic pollution | Science Advances
1 day ago
Abstract Persistent plastic micro- and nanoparticle (MNP) pollution poses a serious threat...
IgLON5 autoimmune antibodies activate Tau via neuronal hyperactivity | Science Advances
1 day ago
Abstract Anti-IgLON5 disease is an autoimmune disease, in which autoantibodies (AABs) against...
From hotspots to hotspaces: Cascaded photonic-plasmonic coupling for SERS-based deep profiling of whole small extracellular vesicles | Science Advances
1 day ago
Abstract The spatial confinement of electromagnetic hotspots (<15 nanometers) in plasmonic nanostructures...
Cell cycle oscillations in a polarity network facilitate state switching by morphogenetic cues | Science Advances
1 day ago
Abstract The establishment of cell form, fate, and function during morphogenesis requires...