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Last updated about 10 hours ago
SLFN14 functions as a P-TEFb inhibitor to modulate the transcription of HIV-1 and cellular genes | Science Advances
about 10 hours ago
Abstract The Schlafen ( SLFN ) gene family encodes different growth regulatory...
Stress granule dynamics govern TOR reactivation and growth recovery during post-heat stress adaptation | Science Advances
about 10 hours ago
Abstract The conserved target of rapamycin (TOR) pathway and stress granules (SGs)...
Direct trapping of the transport-segment DNA by the central domain of type IIA topoisomerases | Science Advances
about 10 hours ago
Abstract Type IIA topoisomerases modulate DNA topology by coordinating the cleavage of...
Clinical-grade iPSC-derived chondrogenic micropellets for treating advanced cartilage defects | Science Advances
about 10 hours ago
Abstract Induced pluripotent stem cell (iPSC)–derived chondrogenic tissues represent a promising alternative...
A nanolaser with extreme dielectric confinement | Science Advances
about 10 hours ago
Abstract The interaction between light and matter can be enhanced by spatially...
Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer’s disease | Science Advances
about 10 hours ago
Abstract Sporadic early-onset Alzheimer’s disease (sEOAD) represents a substantial but less-studied subtype...
Observation of moiré plasmonic skyrmion clusters | Science Advances
about 10 hours ago
Abstract Skyrmions are topological defects belonging to nontrivial homotopy classes in particle...
In situ NMR–guided design of alkaline electrochemical ammonia synthesis | Science Advances
about 10 hours ago
Abstract As a low-carbon and decentralized ammonia synthetic method, lithium-mediated electrochemical synthesis...
Direct recruitment of TONSOKU by the N-terminal tails of histone variants H2A.X and H2A.W coordinates DNA repair | Science Advances
about 10 hours ago
Abstract Histone variants play crucial roles in DNA replication and repair. The...
Humpback whale genomes reflect the increased efficiency of commercial whaling | Science Advances
about 10 hours ago
Abstract Genetic diversity is declining globally, a trend that may particularly affect...
Multimaterial 3D printed soft robots with embedded actuation and sensing | Science Advances
about 10 hours ago
Abstract Soft robots require the seamless integration of actuation and sensing units...
Nanosheet-bridged metal-organic framework membranes for durable hydrocarbon separation under high pressure | Science Advances
about 10 hours ago
Abstract Metal-organic framework (MOF) membranes have garnered notable interest in molecular separation....