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Mechanosensitive biochemical imprinting of the talin interaction with DLC1 regulates RhoA activity and cardiomyocyte remodeling | Science Advances

about 9 hours ago

Abstract During heart disease, the cardiac extracellular matrix (ECM) undergoes a structural...

Retinal gene therapy using epiretinal AAV-containing fibrin hydrogel implants | Science Advances

about 9 hours ago

Abstract Subretinal injection of adeno-associated virus (AAV) is generally more efficacious and...

Dynamic control of electron correlations in photodoped charge-transfer insulators | Science Advances

about 9 hours ago

Abstract The electronic properties of correlated insulators are governed by the strength...

Preparation of ketonyl C-glycosides from designed glycosyl sulfides and styrenes by a radical pathway | Science Advances

about 9 hours ago

Abstract Ketonyl C -glycosides, a vital subclass of alkyl C -glycosides, play...

The role of the North American continent in strengthening the Asian summer monsoon | Science Advances

about 9 hours ago

Abstract Most studies on modern Asian monsoon formation focus on mechanisms arising...

PTPN22-CD45 dual phosphatase retrograde feedback enhances TCR signaling and autoimmunity | Science Advances

about 9 hours ago

Abstract Protein tyrosine phosphatase nonreceptor type 22 (PTPN22) is encoded by a...

Brain stimulation preferentially influences long-range projections | Science Advances

about 9 hours ago

Abstract Advances in brain stimulation have made it possible to target smaller...

HIV-1 manipulates CD96 on CD4+ T cells to subvert antiviral immunity | Science Advances

about 9 hours ago

Abstract HIV-1 evades immune responses by modulating plasma membrane receptors. Using a...

TaGW2-TaVOZ1 module regulates wheat salt tolerance via both E3 ligase–dependent and –independent pathways | Science Advances

about 9 hours ago

Abstract Wheat production is limited by the rapid expansion of salinized arable...

Efficient energy transfer in a hybrid organic-inorganic van der Waals heterostructure | Science Advances

about 9 hours ago

Abstract Two-dimensional (2D) materials offer strong light-matter interaction and design flexibility beyond...

Myo-inositol is a key regulator of avian metabolism: From mechanisms to seasonal behavior | Science Advances

about 9 hours ago

Abstract Being naturally hyperglycemic and insulin insensitive, birds maintain plasma glucose levels...

Repurposing polyethylene terephthalate plastic waste to capture carbon dioxide | Science Advances

about 9 hours ago

Abstract Polyethylene terephthalate (PET) is a ubiquitous polymer with a lack of...