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Strain release through hydrogen bond–mediated layer twisting | Science Advances

2 days ago

Abstract Strain engineering, enabling the precise control over structure and functional properties,...

FuXi-ENS: A machine learning model for efficient and accurate ensemble weather prediction | Science Advances

2 days ago

Abstract Ensemble forecasting is essential for quantifying forecast uncertainty and providing probabilistic...

Implementation of multiparticle quantum speed limits on observables | Science Advances

2 days ago

Abstract The energy-time uncertainty relation limits the maximum speed of quantum system...

Mechanism-based peroxiredoxin 3 inhibitors exploit a covalent warhead for cancer therapy | Science Advances

2 days ago

Abstract Covalent inhibitors that are approved and marketed drugs exploit a wide...

Decoding paradoxical BOLD responses to transcranial ultrasound stimulation with concurrent optoacoustic magnetic resonance imaging | Science Advances

2 days ago

Abstract Focused transcranial ultrasound stimulation (TUS) can affect neural activity with high...

The mechanical response of vinculin | Science Advances

2 days ago

Abstract Vinculin is a mechanosensitive adaptor that links actin to cell-matrix and...

The two-component nuclease-active KELShedu system confers broad antiphage activity via abortive infection | Science Advances

2 days ago

Abstract Bacteriophages and bacteria engage in a continuous evolutionary arms race, driving...

A gastric retentive robotic capsule enables emergency-prepared and responsive oral drug delivery in canine models | Science Advances

2 days ago

Abstract Existing oral drug delivery modalities often fall short in medical emergencies...

BrainSTEM: A single-cell multiresolution fetal brain atlas reveals transcriptomic fidelity of human midbrain cultures | Science Advances

2 days ago

Abstract Protocols for deriving midbrain dopaminergic (mDA) neurons for Parkinson’s disease (PD)...

TH1 effector CD4 T cells rely on IFN-γ production to induce alopecia areata | Science Advances

2 days ago

Abstract Alopecia areata (AA) is an autoimmune disease defined by hair loss...

Direct evidence of natal homing in an Atlantic herring metapopulation | Science Advances

2 days ago

Abstract In times of increased human interventions, knowledge on animal breeding-site fidelity...

Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier | Science Advances

4 days ago

Abstract Archaeological and paleogenomic evidence from the Tibetan Plateau and high-altitude Central...