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Last updated about 7 hours ago

A balance between nucleating and elongating actin filaments controls deformation of protein condensates | Science Advances

about 14 hours ago

Abstract Protein condensates assemble actin filaments into diverse architectures, reminiscent of filopodia...

Reconstituted nascent adhesion condensates drive actin polymerization on supported lipid bilayers | Science Advances

about 14 hours ago

Abstract Nascent adhesions are early integrin-based assemblies that couple the extracellular matrix...

PARP2 deficiency impairs pancreatic cancer progression by promoting genomic instability and antitumor immunity | Science Advances

about 14 hours ago

Abstract Pancreatic cancer represents one of the most lethal tumors, characterized by...

Three cryo-EM structures of complement C3d-bound αMβ2 reveal an unexpected layer of dynamics for αI-containing integrin receptors | Science Advances

about 14 hours ago

Abstract Integrins are heterodimeric membrane proteins acting as mechanosensing receptors. Nine human...

Spatial reorganization of object representations in high-level visual cortex distinguishes working memory from perception | Science Advances

about 14 hours ago

Abstract The visual system balances veridical object perception with flexible visual working...

Hierarchical brain dynamics supporting visual perceptual transitions | Science Advances

about 14 hours ago

Abstract A longstanding debate in consciousness research concerns whether subjective perceptual experiences...

Electronics-free soft robotic minitablet for on-demand gastric molecular sensing and diagnostics in vivo | Science Advances

about 14 hours ago

Abstract Real-time biomarker sensing and molecular sampling in the stomach can transform...

DLP-bioprinted ultrabiomimetic trachea with spatiotemporal angiogenesis regulation for segmental airway reconstruction | Science Advances

about 14 hours ago

Abstract Segmental airway reconstruction requires tracheal grafts that emulate the hierarchical structure...

The pleuroparenchymal fibroelastosis atlas reveals aberrant cell states and their zonation as an alternate roadmap to lung fibrosis | Science Advances

about 14 hours ago

Abstract Pleuroparenchymal fibroelastosis (PPFE) is a progressive interstitial lung disease (ILD) with...

Biogenesis and downstream effects of 3′,5′ and 2′,3′ cAMP isomers in plants | Science Advances

about 14 hours ago

Abstract Cyclic adenosine monophosphate (cAMP) is a fundamental second messenger involved in...

Compound drivers of Antarctic sea ice loss and Southern Ocean destratification | Science Advances

about 14 hours ago

Abstract Antarctic sea ice extent began declining in 2015, reaching its minimum...

Curvature-programmed nitrate electroreduction via single-atom protrusions on quantum dots | Science Advances

about 14 hours ago

Abstract Local geometric constraints have a substantial influence on electronic structure renormalization,...