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Last updated about 6 hours ago

Metabolic rewiring caused by mitochondrial dysfunction promotes mTORC1-dependent skeletal aging | Science Advances

about 13 hours ago

Abstract Decline of mitochondrial respiratory chain (mtRC) capacity is a hallmark of...

A conserved opal termination codon optimizes a temperature-dependent trade-off between protein production and processing in alphaviruses | Science Advances

about 13 hours ago

Abstract Most mosquito-transmitted alphaviruses encode a premature opal termination codon upstream of...

Critical roles of chronic BCR signaling in the differentiation of anergic B cells into age-associated B cells in aging and autoimmunity | Science Advances

about 13 hours ago

Abstract Age-associated B cells (ABCs) with autoreactive properties accumulate with age and...

Discovery of a high-velocity cloud of the Milky Way as a potential dark galaxy | Science Advances

about 13 hours ago

Abstract High-velocity clouds (HVCs) are composed of neutral hydrogen (H I) moving...

Spatial analysis of mitochondrial gene expression reveals dynamic translation hubs and remodeling in stress | Science Advances

about 13 hours ago

Abstract Protein- and RNA-rich bodies contribute to the spatial organization of gene...

Local suppression by link rewiring reveals discontinuous percolation transitions | Science Advances

about 13 hours ago

Abstract When a governor occupies links one by one to globally suppress...

Dihydroxyacetone phosphate generated in the chloroplast mediates the activation of TOR by CO2 and light | Science Advances

about 13 hours ago

Abstract Light and CO 2 assimilation activate the target of rapamycin (TOR)...

Reciprocal phosphorylation between SOAK1 and SOBIR1 fine-tunes receptor-like protein (RLP)–mediated plant immunity | Science Advances

about 13 hours ago

Abstract SUPPRESSOR OF BIR1-1 (SOBIR1) is a receptor-like kinase (RLK) that acts...

Inefficient melt mixing below a fast-spreading ridge revealed by Hess Deep lower gabbros (ODP Leg 147 and IODP Expedition 345) | Science Advances

about 13 hours ago

Abstract The oceanic crust crystallizes from melts formed within a heterogeneous mantle...

Hippocampal perineuronal net degradation identifies prefrontal and striatal circuits involved in schizophrenia-like changes in marmosets | Science Advances

about 13 hours ago

Abstract In schizophrenia, anterior hippocampus (aHipp) overactivity is associated with orbitofrontal cortex...

Statistical analysis of fluorescence intensity transients with Bayesian methods | Science Advances

about 13 hours ago

Abstract Molecular movement and interactions at the single-molecule level, particularly in live...