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Last updated about 7 hours ago

Longitudinal monitoring of type 1 diabetes progression to disease onset | Science Advances

about 7 hours ago

Abstract Preventing autoimmune type 1 diabetes (T1D) necessitates improved monitoring for disease...

RIN3 mutations impairing binding of the Alzheimer’s disease–associated protein BIN1 lead to RAB5 hyperactivation and endosomal pathology | Science Advances

about 7 hours ago

Abstract Alzheimer’s disease (AD) risk is strongly influenced by genetic variants that...

α-Synuclein expression is required for somatodendritic dopamine release and immediate early gene induction | Science Advances

about 7 hours ago

Abstract α-Synuclein (αSyn) is a presynaptic protein of unestablished physiological function that...

Seismic and mineralogical evidence for an iron-rich mega–ultralow-velocity zone beneath Hawai’i | Science Advances

about 7 hours ago

Abstract Mantle plumes beneath major oceanic hot spots appear to be rooted...

Advancing quantum imaging: Electrical tunability enabled by versatile liquid crystals | Science Advances

about 7 hours ago

Abstract Optical image processing techniques like edge detection demonstrate unique superiority in...

Complementary cortical and thalamic contributions to cell type–specific striatal activity dynamics during movement | Science Advances

about 7 hours ago

Abstract Coordinated motor behavior emerges from information flow across brain regions. How...

Efflux pumps control intracellular drug-target kinetics by limiting rebinding in bacteria | Science Advances

about 7 hours ago

Abstract Bacterial efflux pumps are major contributors to multidrug resistance, classically described...

One-stop strabismus digital diagnosis via AI-integrated skin-like and wearable “Eyelectronics” | Science Advances

about 7 hours ago

Abstract Strabismus, affecting ~4% of children, impairs vision and psychosocial health. However,...

LIMCH1-enriched extracellular vesicles promote vascular permeability in early-onset preeclampsia | Science Advances

about 7 hours ago

Abstract Preeclampsia (PE) is a major pregnancy complication characterized by hypertension and...

In situ anchoring 2D hexagonal Zn-MOF on MXene toward robust anode-less 5 V–class Li metal batteries | Science Advances

about 7 hours ago

Abstract Anode-less 5 V–class lithium metal batteries (LMBs) promise high energy density...

Synergizing network topology and solvent compatibility for gels with hyperelasticity and omniadhesion | Science Advances

about 7 hours ago

Abstract In polymeric gels, hyperelasticity and strong adhesion are often required but...