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Last updated 3 days ago
Neuronal HDAC3 knockdown promotes propriospinal detour pathway formation and locomotor recovery in a mouse model of spinal cord injury | Science Translational Medicine
3 days ago
Neuronal HDAC3 knockdown remodels propriospinal relay circuits and improves locomotor recovery after...
Adenovirus and mRNA vaccines as well as mucosal boosting improve protective efficacy against influenza virus challenge in macaques | Science Translational Medicine
3 days ago
Mucosal delivery and gene-based vaccines can both enhance boost responses for influenza...
Antitrypanosomal quinazolines targeting lysyl-tRNA synthetase show partial efficacy in a mouse model of acute Chagas disease | Science Translational Medicine
3 days ago
Quinazolines targeting Trypanosoma cruzi lysyl-tRNA synthetase show partial efficacy in a mouse...
Regulatory T cells attenuate chronic inflammation and cardiac fibrosis in hypertrophic cardiomyopathy | Science Translational Medicine
3 days ago
Regulatory T cells mitigate cardiac fibrosis and dysfunction in familial hypertrophic cardiomyopathy...
Myeloid MAS–driven macrophage efferocytosis promotes resolution in ischemia-stressed mouse and human livers | Science Translational Medicine
3 days ago
MAS receptor modulates the KLF4/MERTK axis in macrophage efferocytosis, thus establishing a...
Myeloma interaction with bone marrow stromal cells suppresses ciliogenesis and osteogenic potential in myeloma bone disease | Science Translational Medicine
3 days ago
Myeloma cell interaction with bone marrow stromal cells leads to impaired ciliogenesis...
Growth arrest specific–6 and angiotoxin receptor–like signaling drive oral regenerative wound repair | Science Translational Medicine
11 days ago
Activation of angiotoxin receptor–like signaling and suppression of focal adhesion kinase allow...
Modeling lesion transition dynamics to clinically characterize patients with clade I mpox in the Democratic Republic of the Congo | Science Translational Medicine
11 days ago
Patients with mpox clade I can be stratified into two groups by...
A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice | Science Translational Medicine
11 days ago
Tumor-targeted cytokine delivery by TAMs establishes a private cross-talk that rescues CAR...
Targeting HBV with RNA interference: Paths to cure | Science Translational Medicine
11 days ago
RNA-targeting therapies hold promise for contributing to HBV cure regimens, but challenges...
A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis | Science Translational Medicine
11 days ago
Beta-secretase 1 promotes the spread of lung cancers to the brain through...
Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity | Science Translational Medicine
11 days ago
An atlas of the cellular and molecular landscape of the juvenile idiopathic...