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Last updated 3 days ago
Growth arrest specific–6 and angiotoxin receptor–like signaling drive oral regenerative wound repair | Science Translational Medicine
3 days ago
Activation of angiotoxin receptor–like signaling and suppression of focal adhesion kinase allow...
Modeling lesion transition dynamics to clinically characterize patients with clade I mpox in the Democratic Republic of the Congo | Science Translational Medicine
3 days ago
Patients with mpox clade I can be stratified into two groups by...
A cross-talk established by tumor-targeted cytokines rescues CAR T cell activity and engages host T cells against glioblastoma in mice | Science Translational Medicine
3 days ago
Tumor-targeted cytokine delivery by TAMs establishes a private cross-talk that rescues CAR...
Targeting HBV with RNA interference: Paths to cure | Science Translational Medicine
3 days ago
RNA-targeting therapies hold promise for contributing to HBV cure regimens, but challenges...
A genome-wide in vivo CRISPR activation screen identifies BACE1 as a therapeutic vulnerability of lung cancer brain metastasis | Science Translational Medicine
3 days ago
Beta-secretase 1 promotes the spread of lung cancers to the brain through...
Synovial tissue atlas in juvenile idiopathic arthritis reveals pathogenic niches associated with disease severity | Science Translational Medicine
3 days ago
An atlas of the cellular and molecular landscape of the juvenile idiopathic...
Ritscher-Schinzel syndrome can be characterized as an endosomal recyclinopathy | Science Translational Medicine
3 days ago
The multiorgan phenotypes found in Ritscher-Schinzel syndrome stem from defective endosomal protein...
A cationic polymer drives glycosaminoglycan assembly and secretion for preclinical osteoarthritis therapy | Science Translational Medicine
10 days ago
A cationic polymer promotes glycosaminoglycan assembly and secretion for treatment of preclinical...
Podocyte YAP and TAZ hyperactivation drives glomerular epithelial proliferative diseases in mice and humans | Science Translational Medicine
10 days ago
Glomerular epithelial proliferative diseases are driven by podocyte YAP and TAZ hyperactivation.
Bile diversion underlies Roux-en-Y antitumor benefits | Science Translational Medicine
10 days ago
Bile diversion in preclinical Roux-en-Y gastric bypass confers its antitumor effects independently...
Podocyte-specific YAP activation triggers crescentic glomerulonephritis through cross-talk with parietal epithelial cells | Science Translational Medicine
10 days ago
YAP overactivation in podocytes triggers proliferation of parietal epithelial cells, driving the...
Metabolic surgery reduces CRC disease progression through circulating bile acid diversion | Science Translational Medicine
10 days ago
Metabolic surgery dampens CRC progression and metastasis through bile acid diversion and...