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Last updated 7 days ago
The orphan receptor GPR84 drives inflammation in Buruli ulcer development | Science Translational Medicine
7 days ago
The GPR84 orphan receptor is a regulator of inflammation and a candidate...
A transcriptional atlas of the pubertal human growth plate reveals two populations of stem cells and direct effect of growth hormone | Science Translational Medicine
7 days ago
This study reveals two populations of cartilage stem cells in both human...
On-demand GLUT3 expression augments CAR T cell metabolic fitness and antitumor efficacy in preclinical models of glioblastoma | Science Translational Medicine
7 days ago
On-demand expression of GLUT3 by CAR T cells boosted their antitumor efficacy...
Selective translation of ZNF281 as part of the integrated stress response system has therapeutic relevance for cardio-oncology | Science Translational Medicine
7 days ago
Therapeutic inhibition of ZNF281 prevents cardiotoxicity, enhances tumor regression, and prevents cancer...
The virus entry inhibitor ARN-75039 provides therapeutic protection against Lassa virus infection in guinea pigs | Science Translational Medicine
7 days ago
Guinea pigs treated with ARN-75039 3 or 7 days after exposure to...
Autophagosome-targeting single-domain antibody clears tau in patient-derived neurons and improves motor function in tauopathy mice | Science Translational Medicine
7 days ago
A brain-penetrant single-domain antibody degrader clears pathological tau and restores motor function...
Retraction of the Research Article “Targeted immunotherapy for HER2-low breast cancer with 17p loss” | Science Translational Medicine
7 days ago
On 10 February 2021, Science Translational Medicine published the Research Article “Targeted...
Corticosteroid resistance is predetermined by early immune response dynamics at acute graft-versus-host disease onset | Science Translational Medicine
14 days ago
Steroid-resistant acute graft-versus-host disease is set at disease onset and leads to...
Design of a neutralizing and protective pan–encephalitic alphavirus receptor decoy protein | Science Translational Medicine
14 days ago
An engineered protein receptor decoy protects mice from lethal infection caused by...
Real-time intraocular pressure monitoring and responsive drug release in preclinical models by an all-polymer smart contact lens | Science Translational Medicine
14 days ago
Battery- and electronics-free theranostic contact lens tracks IOP and autonomously delivers drugs...
Keratin 16 inhibits type I interferon responses in differentiating keratinocytes of stressed and diseased skin | Science Translational Medicine
14 days ago
Keratin 16 suppresses type I interferon and innate immunity in the skin...
A human iPSC model of tauopathies engineered for 4R tau isoform expression endogenously develops late-stage neuronal tau pathology | Science Translational Medicine
14 days ago
A human iPSC–derived tauopathy model endogenously recapitulates late-stage pathology and enables translational...