Science Translational Medicine current issue

[Research Articles] Dietary simple sugars alter microbial ecology in the gut and promote colitis in mice

2 days ago

The higher prevalence of inflammatory bowel disease (IBD) in Western countries points...

[Research Articles] A modified drug regimen clears active and dormant trypanosomes in mouse models of Chagas disease

2 days ago

A major contributor to treatment failure in Chagas disease, caused by infection...

[Errata] Erratum for the Research Article: "Exosomes secreted by hiPSC-derived cardiac cells improve recovery from myocardial infarction in swine" by L. Gao, L. Wang, Y. Wei, P. Krishnamurthy, G. P. Walcott, P. Menasche, J. Zhang

2 days ago

[Editors' Choice] Early stage EGFR-mutated lung cancer gets a targeted treatment

2 days ago

Osimertinib improves disease-free survival for patients with early stage EGFR-mutated non-small cell...

[Editors' Choice] Bispecific CAR T cells have a dual grasp on tumors

2 days ago

Bispecific CD19/CD20 chimeric antigen receptor T cells show high efficacy in B...

[Editors' Choice] Encapsulating a leukemia vaccine

2 days ago

A self-healing microcapsule loaded with leukemia-associated antigens, epitope peptides, and PD-1 antibody...

[Research Articles] Nonhuman primates exposed to Zika virus in utero are not protected against reinfection at 1 year postpartum

2 days ago

There is limited information about the impact of Zika virus (ZIKV) exposure...

[Research Articles] Mohawk is a transcription factor that promotes meniscus cell phenotype and tissue repair and reduces osteoarthritis severity

2 days ago

Meniscus tears are common knee injuries and a major osteoarthritis (OA) risk...

[Research Articles] Targeted inhibition of PI3 kinase/mTOR specifically in fibrotic lung fibroblasts suppresses pulmonary fibrosis in experimental models

2 days ago

Idiopathic pulmonary fibrosis (IPF) is a lethal disease with an average life...

[Research Articles] A probiotic yeast-based immunotherapy against Clostridioides difficile infection

2 days ago

Antibiotic-resistant Clostridioides difficile is an anaerobic Gram-positive bacterium that colonizes the colon...

[Research Articles] Metabolic reprogramming of donor T cells enhances graft-versus-leukemia effects in mice and humans

2 days ago

Acute myeloid leukemia (AML) relapse after allogeneic hematopoietic cell transplantation (allo-HCT) has...

[Editors' Choice] Treating diabetes with electromagnetic fields

9 days ago

Exposure to electromagnetic fields increases insulin sensitivity in diabetic mice, with altered...