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Last updated 2 days ago

Primary cilia mediate skeletogenic BMP and Hedgehog signaling in heterotopic ossification | Science Translational Medicine

2 days ago

Aberrant BMP and Hedgehog signaling mediated by primary cilia drive heterotopic ossification.

Human iPSC–liver organoid transplantation reduces fibrosis through immunomodulation | Science Translational Medicine

2 days ago

Human iPSC–derived liver organoid transplantation improves preclinical liver fibrosis and function by...

Targeting ferritinophagy impairs quiescent cancer stem cells in acute myeloid leukemia in vitro and in vivo models | Science Translational Medicine

2 days ago

Targeting quiescent leukemic stem cells through NCOA4-dependent ferritinophagy inhibition may improve therapeutic...

Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70 | Science Translational Medicine

2 days ago

Adjuvanting BNT162b2 with IL-12p70–MOP amplified and extended the durability of vaccine-elicited immune...

Improving vaccine equity by increasing vaccine thermostability | Science Translational Medicine

2 days ago

Enhancing the thermostability profiles of existing and new vaccine technologies could have...

Vasohibin inhibition improves myocardial relaxation in a rat model of heart failure with preserved ejection fraction | Science Translational Medicine

9 days ago

Blocking α-tubulin detyrosination with a small-molecule inhibitor improves myocardial relaxation in the...

Knockdown of swine leukocyte antigen expression in porcine lung transplants enables graft survival without immunosuppression | Science Translational Medicine

9 days ago

Down-regulation of swine leukocyte antigen expression supports graft survival after allogeneic lung...

Comparative single-cell analysis reveals IFN-γ as a driver of respiratory sequelae after acute COVID-19 | Science Translational Medicine

9 days ago

Comparative scRNA-seq analysis, combined with functional experiments in an animal model, identified...

Molecular dissection of cobra venom highlights heparinoids as an antidote for spitting cobra envenoming | Science Translational Medicine

9 days ago

Spitting cobra venom cytotoxins cause tissue damage through a common heparin-sensitive mechanism.