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Last updated about 23 hours ago

Sotatercept reduces bone morphogenetic protein signaling in patients with pulmonary arterial hypertension | Science Translational Medicine

about 23 hours ago

A BMP target engagement biomarker panel, developed through the StratosPHere 1 study...

Transcranial ultrasound stimulation of motor networks in Parkinson’s disease informed by local field potential dynamics | Science Translational Medicine

about 23 hours ago

TUS can alter subthalamic activity in a target-specific, frequency band–specific, and brain...

Urinary fluorogenic reporters for noninvasive detection and staging of kidney fibrosis | Science Translational Medicine

about 23 hours ago

Fibrogenesis sensing reporters provide a noninvasive approach for identification of kidney fibrosis...

Treating the immune system to repair the brain | Science Translational Medicine

about 23 hours ago

Targeting the systemic immune system in Alzheimer’s disease restores immune-mediated neuroprotection that...

In vivo adenine base editing ameliorates Dravet syndrome phenotypes in a mouse model | Science Translational Medicine

8 days ago

Through direct correction of a mutation causing Dravet syndrome, adenine base editing...

Sensory nerves protect against preclinical tendinopathic changes through FGF1 signaling | Science Translational Medicine

8 days ago

Somatosensory neurons prevent tendon degeneration by FGF1-mediated mesenchymal and macrophage regulation.

Prime editing of a pathogenic Scn1a allele ameliorates seizure phenotypes in a GEFS+ mouse model | Science Translational Medicine

8 days ago

Prime editing corrects a pathogenic human SCN1A mutation in mice, reducing seizure...