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Anti-FAP CAR T cells produced in vivo reduce fibrosis and restore liver homeostasis in metabolic dysfunction–associated steatohepatitis | Science Translational Medicine
1 day ago
CAR T cells generated in vivo by T cell–targeted mRNA-LNP delivery eliminated...
In silico screening and preclinical validation identify bavisant as a therapeutic candidate for multiple sclerosis | Science Translational Medicine
1 day ago
The histamine receptor H3 antagonist bavisant promotes neuroprotection and remyelination in cell...
Epigenetic dysregulation of metabolic programs mediates liposarcoma cell plasticity | Science Translational Medicine
1 day ago
Integrated multiome analysis identifies loss of PPARG2 as a driver of liposarcoma...
Erratum for Report “APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia” by G. Sienski et al. | Science Translational Medicine
1 day ago
In the Report “APOE4 disrupts intracellular lipid homeostasis in human iPSC-derived glia”...
Inhaled nitric oxide at 300 ppm treats multidrug-resistant Pseudomonas pneumonia in swine and is safe in humans | Science Translational Medicine
1 day ago
A swine and human study shows that treating multidrug-resistant Pseudomonas aeruginosa pneumonia...
Quantitative assessment of neonatal health using dried blood spot metabolite profiles and deep learning | Science Translational Medicine
1 day ago
Newborn screen metabolites encapsulate the risk for adverse outcomes of prematurity through...
Dual FAK and EPHA2 targeting by brigatinib tackles PARP inhibitor adaptive survival response in high-grade serous ovarian cancer | Science Translational Medicine
9 days ago
Brigatinib enhances PARPi response in HGSOC by disrupting adaptive survival of malignant...
Combined inhibition of FACT and BET disrupts transcription to suppress tumor growth in mouse models of diffuse midline glioma | Science Translational Medicine
9 days ago
FACT and BET inhibition in diffuse midline glioma drives tumor suppression and...
Endothelial cell–released CD93 contributes to podocyte injury in idiopathic nephrotic syndrome | Science Translational Medicine
9 days ago
Soluble CD93 contributes to podocyte injury, and CD93 blockade emerges as a...
An antibody cocktail targeting conserved, nonoverlapping epitopes prevents viral escape and confers protection against RSV in vivo | Science Translational Medicine
9 days ago
An antibody cocktail targeting conserved epitopes on the RSV A and B...
Erratum for the Research Article “Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines control HPV-associated tumors in mice” by J. Ramos da Silva et al. | Science Translational Medicine
9 days ago
In the Research Article “Single immunizations of self-amplifying or non-replicating mRNA-LNP vaccines...
Brain-derived tau for monitoring brain injury in acute ischemic stroke | Science Translational Medicine
9 days ago
Brain-derived tau in plasma reflects the extent of brain injury in acute...