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Periadventitial delivery of mesenchymal stem cells improves vascular remodeling and maturation in arteriovenous fistulas | Science Translational Medicine

1 day ago

Vascular remodeling and maturation in arteriovenous fistulas are improved by mesenchymal stem...

Dietary saturated fatty acids promote lung myeloid cell inflammasome activation and IL-1β–mediated inflammation in mice and humans | Science Translational Medicine

1 day ago

Obesity-associated saturated long-chain fatty acids regulate lung macrophage phenotype and function at...

NF1-depleted ER+ breast cancers are differentially sensitive to CDK4/6 inhibitors | Science Translational Medicine

1 day ago

Coactivation of ER and RAS signaling in NF1-depleted ER+ breast cancer promotes...

Follicular regulatory T cells promote experimental autoimmune encephalomyelitis by supporting B cell egress from germinal centers | Science Translational Medicine

1 day ago

Follicular regulatory T cells promote B cell–mediated experimental neuroinflammation and are associated...

Resolving fibrosis by stimulating HSC-dependent extracellular matrix degradation | Science Translational Medicine

1 day ago

Targeting acid ceramidase enhances collagen degradation by hepatic stellate cells via PKCα...

CAR Treg cells mediate linked suppression and infectious tolerance in islet transplantation in mice | Science Translational Medicine

8 days ago

HLA-A2–specific chimeric antigen receptor–engineered regulatory T cells tolerize diabetogenic T cells and...

Ultrahigh-concentration biologic therapeutics enabled by spray drying with a glassy surfactant excipient | Science Translational Medicine

8 days ago

A copolymer excipient enables stable, ultrahigh-concentration protein formulations for subcutaneous injection.

High binding potency overcomes the requirement of Fc effector functions for broadly reactive anti-alphavirus antibodies | Science Translational Medicine

8 days ago

Binding potency of broadly reactive anti-alphavirus antibodies to infected cells dictates the...

Synchronized dynamics of dengue across the Americas | Science Translational Medicine

8 days ago

Dengue has strong synchrony across the Americas, indicating that a mix of...