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A PIVOT towards single-cell functional genetic screening in plants
1 day ago
Nature Biotechnology, Published online: 05 May 2026; doi:10.1038/s41587-026-03141-0We developed PIVOT, a single-cell...
A single-cell screening platform accelerates functional genetics in plants
2 days ago
Nature Biotechnology, Published online: 05 May 2026; doi:10.1038/s41587-026-03094-4A pooled, cell-based, genetic screening...
Thymus renaissance poised to boost health and longevity
2 days ago
Nature Biotechnology, Published online: 05 May 2026; doi:10.1038/s41587-026-03137-wEvidence linking thymic function with...
Digital twins of ex vivo human lungs enable accurate and personalized evaluation of therapeutic efficacy
3 days ago
Nature Biotechnology, Published online: 04 May 2026; doi:10.1038/s41587-026-03121-4A comprehensive ‘digital twin’ of...
DNA-guided CRISPR–Cas12a effectors for programmable RNA recognition and cleavage
6 days ago
Nature Biotechnology, Published online: 01 May 2026; doi:10.1038/s41587-026-03120-5Synthetic DNA guides (crDNA) reprogram...
TxPert: using multiple knowledge graphs for prediction of transcriptomic perturbation effects
6 days ago
Nature Biotechnology, Published online: 01 May 2026; doi:10.1038/s41587-026-03113-4TxPert predicts unseen single transcriptomic...
Tracing the rise of biomedical foundation models
7 days ago
Nature Biotechnology, Published online: 30 April 2026; doi:10.1038/s41587-026-03135-yA survey of biological foundation...
Tuning the immune response to mRNA vaccines
8 days ago
Nature Biotechnology, Published online: 29 April 2026; doi:10.1038/s41587-026-03125-0A strategy to control translation...
mRNA vaccine immunity is enhanced by hepatocyte detargeting and not dependent on dendritic cell expression
8 days ago
Nature Biotechnology, Published online: 29 April 2026; doi:10.1038/s41587-026-03099-zmRNA vaccine efficacy is enhanced...
Historic FDA approval brings first gene therapy for genetic deafness
9 days ago
Nature Biotechnology, Published online: 28 April 2026; doi:10.1038/s41587-026-03145-wThe first-of-its-kind genetic medicine treats...
A multiobjective AI model for LNP engineering enhances tissue-selective mRNA delivery
9 days ago
Nature Biotechnology, Published online: 28 April 2026; doi:10.1038/s41587-026-03109-0AI targets lipid nanoparticles to...
Pool-packaged AAV libraries exhibit extensive length-dependent and homology-dependent chimerism
9 days ago
Nature Biotechnology, Published online: 28 April 2026; doi:10.1038/s41587-026-03097-1Pooled production of recombinant AAV...