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Transferable genetic toolsets for nonmodel gut Clostridia enable in vivo reversible control of metabolite production

1 day ago

Nature Biotechnology, Published online: 25 August 2026; doi:10.1038/s41587-026-03269-zGenetic engineering tools are developed...

Adaptive model-guided protein evolution with sparse data optimizes compact eukaryotic genome editors

3 days ago

Nature Biotechnology, Published online: 24 August 2026; doi:10.1038/s41587-026-03272-4Computational protein evolution with sparse...

Bonsai reconstructs tree representations for distortion-free visualization and exploration of high-dimensional data

5 days ago

Nature Biotechnology, Published online: 21 August 2026; doi:10.1038/s41587-026-03220-2High-dimensional data are visualized through...

Enhanced antitumor immunity of mRNA vaccines by bioorthogonal-like delayed activation of exogeneous STING

7 days ago

Nature Biotechnology, Published online: 19 August 2026; doi:10.1038/s41587-026-03224-ymRNA vaccine efficacy is enhanced...

A blinded, prospective benchmark of in silico antibody discovery anchored to experimental affinity and developability

7 days ago

Nature Biotechnology, Published online: 19 August 2026; doi:10.1038/s41587-026-03238-6A prospective, blinded competition is...

High-throughput synthesis of DNA fragments by molecular self-assembly of overlapping oligonucleotides

7 days ago

Nature Biotechnology, Published online: 19 August 2026; doi:10.1038/s41587-026-03266-2DNA libraries are synthesized at...

Massive-scale parallel gene synthesis with oligonucleotide hybridization

7 days ago

Nature Biotechnology, Published online: 19 August 2026; doi:10.1038/s41587-026-03290-2MOSAIC is a high-throughput gene...

From reading to writing

7 days ago

Nature Biotechnology, Published online: 19 August 2026; doi:10.1038/s41587-026-03300-3DNA writing is entering a...

Author Correction: Derivation of embryonic stem cells across avian species

7 days ago

Nature Biotechnology, Published online: 19 August 2026; doi:10.1038/s41587-026-03309-8Author Correction: Derivation of embryonic...

Lessons from drug revenue life cycles: distributions across modalities and therapeutic areas

8 days ago

Nature Biotechnology, Published online: 18 August 2026; doi:10.1038/s41587-026-03278-yAn analysis of FDA-approved drugs...

Editor’s pick: Dispatch Biotherapeutics

8 days ago

Nature Biotechnology, Published online: 18 August 2026; doi:10.1038/s41587-026-03293-zEach year, Nature Biotechnology highlights...

A scalable platform to discover and characterize substrates of molecular glue degraders

9 days ago

Nature Biotechnology, Published online: 17 August 2026; doi:10.1038/s41587-026-03256-4Molecular glue degraders (MGDs) induce...