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Last updated about 22 hours ago

Elucidating lipid nanoparticle properties and structure through biophysical analyses

about 22 hours ago

Nature Biotechnology, Published online: 23 October 2025; doi:10.1038/s41587-025-02855-xGuidance for optimizing lipid nanoparticle...

Live imaging of late-stage preimplantation human embryos reveals de novo mitotic errors

about 22 hours ago

Nature Biotechnology, Published online: 23 October 2025; doi:10.1038/s41587-025-02851-1A method to label cultured...

Overcoming barriers to the wide adoption of single-cell large language models in biomedical research

about 22 hours ago

Nature Biotechnology, Published online: 23 October 2025; doi:10.1038/s41587-025-02846-yTransformer-based large language models are...

Discovery and engineering of retrons for precise genome editing

about 22 hours ago

Nature Biotechnology, Published online: 23 October 2025; doi:10.1038/s41587-025-02879-3A metagenomic screen identifies retron...

RNA structure modulates Cas13 activity and enables mismatch detection

about 22 hours ago

Nature Biotechnology, Published online: 23 October 2025; doi:10.1038/s41587-025-02868-6An effective CRISPR RNA occlusion...

Long-term imaging of cell divisions in human preimplantation embryos

about 22 hours ago

Nature Biotechnology, Published online: 23 October 2025; doi:10.1038/s41587-025-02841-3An optimized approach for live...

Tissue and cellular spatiotemporal dynamics in colon aging

2 days ago

Nature Biotechnology, Published online: 22 October 2025; doi:10.1038/s41587-025-02830-6cSplotch compares spatial transcriptomics data...

Integrated epigenetic and genetic programming of primary human T cells

3 days ago

Nature Biotechnology, Published online: 21 October 2025; doi:10.1038/s41587-025-02856-wMultiplexed editing in primary human...

AlphaDIA enables DIA transfer learning for feature-free proteomics

3 days ago

Nature Biotechnology, Published online: 21 October 2025; doi:10.1038/s41587-025-02791-wAn open-source platform for data-independent...

Editor’s pick: Constructive Bio

4 days ago

Nature Biotechnology, Published online: 20 October 2025; doi:10.1038/s41587-025-02850-2Each year, Nature Biotechnology highlights...

Tumor-on-chip models of CAR-T cell therapy

7 days ago

Nature Biotechnology, Published online: 17 October 2025; doi:10.1038/s41587-025-02819-1Two seminal studies report a...

A tumor-on-a-chip for in vitro study of CAR-T cell immunotherapy in solid tumors

7 days ago

Nature Biotechnology, Published online: 17 October 2025; doi:10.1038/s41587-025-02845-zThe interactions of CAR-T cells...