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Last updated 25 days ago
Affinity maturation of antibody responses is mediated by differential plasma cell proliferation | Science
25 days ago
Increased antibody affinity over time after vaccination, known as affinity maturation, is...
Identification of antigen-presenting cell–T cell interactions driving immune responses to food | Science
25 days ago
The intestinal immune system must concomitantly tolerate food and commensals and protect...
Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription | Science
about 1 month ago
During transcription, RNA polymerase II traverses through chromatin, and post-translational modifications including...
Confronting risks of mirror life | Science
about 1 month ago
Broad discussion is needed to chart a path forward.
Antiviral signaling of a type III CRISPR-associated deaminase | Science
about 1 month ago
Prokaryotes have evolved diverse defense strategies against viral infection, such as foreign...
Nutrient-driven histone code determines exhausted CD8+ T cell fates | Science
about 1 month ago
ACLY-deficient CAR T cells targeting the tumor-associated antigen disialoganglioside GD2 (GD2 CAR...
Recent global temperature surge intensified by record-low planetary albedo | Science
about 1 month ago
In 2023, the global mean temperature soared to almost 1.5K above the...
Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin | Science
about 1 month ago
Maintaining genome integrity is an essential and challenging process. RAD51 recombinase, the...
A panoramic view of cell population dynamics in mammalian aging | Science
about 2 months ago
To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome...
Natural selection could determine whether Acropora corals persist under expected climate change | Science
about 2 months ago
Marine heatwaves are intensifying under climate change, exposing populations of reef-building corals...
Rapid in silico directed evolution by a protein language model with EVOLVEpro | Science
about 2 months ago
Directed protein evolution is central to biomedical applications but faces challenges like...
Loss of Earth’s old, wise, and large animals | Science
about 2 months ago
Earth’s old animals are in decline. Despite this, emerging research is revealing...