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Last updated 5 days ago

Synergy between regulatory elements can render cohesin dispensable for distal enhancer function | Science

5 days ago

Enhancers are critical genetic elements controlling transcription from promoters, yet how they...

Characterizing transport in a quantum gas by measuring Drude weights | Science

5 days ago

Transport properties define materials as insulators, metals, or superconductors. A fundamental parameter...

Structural basis for the recruitment and selective phosphorylation of Akt by mTORC2 | Science

5 days ago

The mTOR protein kinase forms two multiprotein complexes, mTORC1 and mTORC2, that...

Intracellular competition shapes plasmid population dynamics | Science

12 days ago

From populations of multicellular organisms to selfish genetic elements, conflicts between levels...

A global screen for magnetically induced neuronal activity in the pigeon brain | Science

12 days ago

How animals detect the Earth’s magnetic field remains a mystery in sensory...

Pan-family pollen signals control an interspecific stigma barrier across Brassicaceae species | Science

12 days ago

Pre-zygotic interspecific incompatibility prevents hybridization between species limiting interbreeding strategies for crop...

Recurrent acquisition of nuclease-protease pairs in antiviral immunity | Science

19 days ago

Antiviral immune systems diversify by integrating new genes into existing pathways, creating...

Three-component assembly and structure–function relationships of (–)-gukulenin A | Science

19 days ago

α-Tropolones comprise an unsaturated seven-membered ring bearing a hydroxyl substituent adjacent to...

A whole-brain single-cell atlas of circadian neural activity in mice | Science

19 days ago

The mammalian brain comprises numerous anatomical regions with distinct functions despite their...

Different repair pathways support intact or truncated insertions by R2 retrotransposon protein | Science

19 days ago

Non-LTR retrotransposon proteins copy their RNA template into a genome via coordinated...

Termination of the integrated stress response | Science

19 days ago

Stress responses enable cells to detect, adapt to, and survive challenges. The...

NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT | Science

26 days ago

Cells generate purine nucleotides through de novo purine biosynthesis (DNPB) and purine...