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Last updated 4 days ago
TranscriptFormer: A generative cell atlas across 1.5 billion years of evolution | Science
4 days ago
Single-cell transcriptomics is revolutionizing our understanding of cellular diversity, yet comparing transcriptional...
Induction of broadly neutralizing HIV antibodies by a two-step mechanism informs vaccine design | Science
4 days ago
A major obstacle confronting HIV-1 vaccine and cure research is the lack...
A 481-meter-high landslide-tsunami in a cruise ship–frequented Alaska fjord | Science
5 days ago
Early in the morning of 10 August 2025, a >64 × 106...
Severe obesity in human HFpEF alters contractile protein function and organization | Science
18 days ago
Heart failure with preserved ejection fraction (HFpEF) causes substantial morbidity and mortality...
Microtubule dynamics control the direction of cardiomyocyte growth | Science
18 days ago
The adult heart grows by addition of sarcomeres along the length or...
Stopping phase reveals abrupt arrest of large strike-slip earthquakes | Science
18 days ago
Earthquake magnitude is controlled by where and when rupture propagation stops. Yet...
Structural N- and O-glycans revealed by high-resolution cryo-EM analysis of tubular mastigonemes | Science
18 days ago
The chemical complexity and non-templated biosynthesis of glycans have posed significant challenges...
Protein-templated synthesis of dinucleotide repeat DNA by an antiphage reverse transcriptase | Science
25 days ago
Defense-associated reverse transcriptases (DRTs) are widespread bacterial anti-phage systems that use unconventional...
Device-scaling constraints imposed by the van der Waals gap formed in two-dimensional materials | Science
25 days ago
Transistor miniaturization requires controlling gate leakage through ultrathin dielectrics and minimizing source/drain...
Reimagining human-centric drug development with new approach methodologies | Science
25 days ago
Despite unprecedented technological progress, most drug candidates continue to fail in clinical...
Divergent and programmable skeletal remodeling of complex macrocycles with a small method set | Science
about 1 month ago
The bioactivity of complex organic macrocycles can vary unpredictably with their three-dimensional...
Editorial Expression of Concern for the Research Article “Kinetic organization of the genome revealed by ultraresolution multiscale live imaging” by J. Lee et al. | Science
about 1 month ago
On 18 September 2025, Science published the Research Article "Kinetic organization of...