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Nature Methods
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Last updated 2 days ago
FILM: mapping organellar metabolism by mid-infrared photothermal-modulated fluorescence
2 days ago
Nature Methods, Published online: 07 May 2026; doi:10.1038/s41592-026-03090-1FILM is a mid-infrared photothermal...
‘FILMing’ the metabolic landscape of individual cell organelles
2 days ago
Nature Methods, Published online: 07 May 2026; doi:10.1038/s41592-026-03091-0Optical boxcar-enhanced fluorescence-detected mid-infrared photothermal...
$${\bf{Micro}}{{\mathbb{S}}}{\bf{plit}}$$ Micro S plit : semantic unmixing of fluorescent microscopy data
4 days ago
Nature Methods, Published online: 05 May 2026; doi:10.1038/s41592-026-03082-1$${\rm{Micro}}{\mathbb{S}}{\rm{plit}}$$ M i c r...
Unsupervised transfer learning enables multi-animal tracking without training annotation
5 days ago
Nature Methods, Published online: 04 May 2026; doi:10.1038/s41592-026-03051-8UDMT is a multi-animal tracker...
Double robustness
5 days ago
Nature Methods, Published online: 04 May 2026; doi:10.1038/s41592-026-03099-6It is not certain that...
Call your AI agent
8 days ago
Nature Methods, Published online: 01 May 2026; doi:10.1038/s41592-026-03088-9AI agent systems are now...
Resolving sensitivity, specificity and signal contamination in Xenium spatial transcriptomics
9 days ago
Nature Methods, Published online: 30 April 2026; doi:10.1038/s41592-026-03089-8This study investigates technical noise...
eSIG-Net: an interaction language model that decodes the protein code of single mutations
10 days ago
Nature Methods, Published online: 29 April 2026; doi:10.1038/s41592-026-03086-xeSIG-Net is an interaction language...
Single-molecule localization and diffusivity microscopy reveals dynamic biomolecular organization in living cells
11 days ago
Nature Methods, Published online: 28 April 2026; doi:10.1038/s41592-026-03078-xSingle-molecule localization and diffusivity microscopy...
Spatial 5mC-seq profiling of embryos and decidua after implantation in mammals
12 days ago
Nature Methods, Published online: 27 April 2026; doi:10.1038/s41592-026-03079-wSpatial 5mC-seq enables nonbiased, spatiotemporal...
Self-localized ultrafast pencil beam for volumetric multiphoton imaging
12 days ago
Nature Methods, Published online: 27 April 2026; doi:10.1038/s41592-026-03067-0A self-localized, ultrafast pencil beam...
A self-organized pencil beam that can be used for fast volumetric imaging
12 days ago
Nature Methods, Published online: 27 April 2026; doi:10.1038/s41592-026-03094-xWe observed that a stable...