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Nature Methods
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Last updated about 15 hours ago
Carta offers a computational approach to inference of differentiation maps from cell lineages
about 15 hours ago
Nature Methods, Published online: 15 December 2025; doi:10.1038/s41592-025-02904-yThe Carta algorithm infers a...
Systematic scRNA-seq screens profile neural organoid response to morphogens
about 17 hours ago
Nature Methods, Published online: 15 December 2025; doi:10.1038/s41592-025-02927-5This Resource provides a detailed...
MultiCell: geometric learning in multicellular development
about 17 hours ago
Nature Methods, Published online: 15 December 2025; doi:10.1038/s41592-025-02983-xMultiCell is a deep learning...
Bio-friendly and high-precision super-resolution imaging through self-supervised reconstruction structured illumination microscopy
4 days ago
Nature Methods, Published online: 12 December 2025; doi:10.1038/s41592-025-02966-ySelf-supervised reconstruction structured illumination microscopy...
Computational strategies for cross-species knowledge transfer
4 days ago
Nature Methods, Published online: 12 December 2025; doi:10.1038/s41592-025-02931-9This Perspective reviews computational methods...
Benchmarking algorithms for generalizable single-cell perturbation response prediction
5 days ago
Nature Methods, Published online: 11 December 2025; doi:10.1038/s41592-025-02980-0This analysis performs comprehensive comparisons...
Scikit-bio: a fundamental Python library for biological omic data analysis
5 days ago
Nature Methods, Published online: 11 December 2025; doi:10.1038/s41592-025-02981-zScikit-bio: a fundamental Python library...
Novae: a graph-based foundation model for spatial transcriptomics data
5 days ago
Nature Methods, Published online: 10 December 2025; doi:10.1038/s41592-025-02899-6Novae, a self-supervised graph attention...
Systematic evaluation of computational tools for multitype RNA modification detection using nanopore direct RNA sequencing
6 days ago
Nature Methods, Published online: 10 December 2025; doi:10.1038/s41592-025-02974-yThis analysis benchmarked computational tools...
FACED 2.0 enables large-scale voltage and calcium imaging in vivo
7 days ago
Nature Methods, Published online: 09 December 2025; doi:10.1038/s41592-025-02925-7FACED 2.0 builds on and...
The virtual cell
7 days ago
Nature Methods, Published online: 08 December 2025; doi:10.1038/s41592-025-02951-5Virtual cells based on artificial...
Bridging smart microscopy with genomics
7 days ago
Nature Methods, Published online: 08 December 2025; doi:10.1038/s41592-025-02986-8Bridging smart microscopy with genomics