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Last updated 7 days ago

The establishment of nuclear organization in mouse embryos is orchestrated by multiple epigenetic pathways

7 days ago

In vivo screening in mouse embryos provides insights into the functional interplay...

Hypothalamic PNOC/NPY neurons constitute mediators of leptin-controlled energy homeostasis

7 days ago

Activation of PNOCARC neurons promotes feeding. Here, Solheim et al. describe PNOC...

Regional differences in progenitor metabolism shape brain growth during development

7 days ago

Brain-wide birthdate mapping reveals that while hindbrain neurogenesis is transient, forebrain neurogenesis...

Encoding and decoding selectivity and promiscuity in the human chemokine-GPCR interaction network

7 days ago

Sequence and structure-based analysis highlight the molecular principles driving chemokine-GPCR selectivity and...

Selective requirement of glycosphingolipid synthesis for natural killer and cytotoxic T cells

7 days ago

Cytotoxic cells, especially natural killer cells, have a particular dependence on glycosphingolipid...

Transcriptional regulation by PHGDH drives amyloid pathology in Alzheimer’s disease

7 days ago

This study uncovers a previously unknown role for PHGDH in Alzheimer’s disease...

Tissue geometry spatiotemporally drives bacterial infections

7 days ago

Tissue-geometry-regulated cellular traction forces trigger the activation of Piezo1 and its co-localization...

Integrating reproductive states and social cues in the control of sociosexual behaviors

7 days ago

A subset of neurons in the medial prefrontal cortex is shown to...

Macrophages direct location-dependent recall of B cell memory to vaccination

7 days ago

Subcapsular sinus macrophages in the draining lymph node help retain resident memory...

Extrachromosomal DNA replication and maintenance couple with DNA damage pathway in tumors

7 days ago

This study demonstrates that extrachromosomal DNA (ecDNA) replication induces DNA double-strand breaks...

50,000 years of evolutionary history of India: Impact on health and disease variation

7 days ago

A genomic study of 2,762 individuals from India offers important insights into...