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Last updated 11 days ago
A Validated Regulatory Network for Th17 Cell Specification
11 days ago
(Cell 151, 289–303; October 12, 2012)
VIVIT: Resolving trans-scale volumetric biological architectures via ionic glassy tissue
11 days ago
Leveraging the chemical properties of ionic liquids, VIVIT transforms biological tissue into...
Long shared haplotypes identify the southern Urals as a primary source for the 10th-century Hungarians
11 days ago
Genome-wide ancient DNA data from early medieval populations across the broader Ural...
Identification of gut microbial bile acid metabolic enzymes via an AI-assisted pipeline
11 days ago
Ding et al. report an AI-assisted workflow that enables top-down, cultivation-independent identification...
Vagal blockade of the brain-liver axis deters cancer-associated cachexia
11 days ago
Vagal dysfunction mediates the impact of tumor on liver metabolism, leading to...
A split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into ubiquitin-coated nucleoprotein particles
11 days ago
Grabarczyk et al. show the structure and mechanism of a non-canonical ubiquitin...
HT SpaceM: A high-throughput and reproducible method for small-molecule single-cell metabolomics
11 days ago
Single-cell metabolomics (SCM) can probe metabolic heterogeneity but is hindered by low...
Design of soluble Notch agonists that drive T cell development and boost immunity
11 days ago
Mout et al. report the development of soluble Notch agonists that can...
A generative deep learning approach to de novo antibiotic design
11 days ago
A generative AI platform is developed for de novo antibiotic design, yielding...
The essential host genome for Cryptosporidium survival exposes metabolic dependencies that can be leveraged for treatment
11 days ago
An arrayed microscopy-based CRISPR screen revealed host genes affecting multiple infection phenotypes...
The small GTPase Ran defines nuclear pore complex asymmetry
11 days ago
Nuclear pore complexes at the nuclear envelope are asymmetric structures, whereas those...
Prevalent mesenchymal drift in aging and disease is reversed by partial reprogramming
11 days ago
Loss of cellular identity across aging and disease is linked to a...