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Last updated 1 day ago
Structural and functional characterizations of infectivity and immune evasion of SARS-CoV-2 Omicron
1 day ago
(Cell 185, 860–871.e1–e4; March 3, 2022)
Systemic immune activity occurs during human immune system maturation
1 day ago
Profiling of immune cells from consecutive developmental time points in second-trimester fetuses...
Protein restriction reprograms the multi-organ proteomic landscape of mouse aging
1 day ago
Comprehensive proteomic analysis of 41 mouse tissues reveals tissue-specific aging hallmarks and...
The genomic footprints of wild Saccharum species trace domestication, diversification, and modern breeding of sugarcane
1 day ago
Genomic analyses of 390 accessions reveal the domestication history of highly polyploid...
Shaping pit structure in vessel walls sustains xylem hydraulics and grain yield
1 day ago
The three-dimensional geometry of pits, the nanoscale structures in plant vessel walls...
Pathway-selective 5-HT1AR agonist as a rapid antidepressant strategy
1 day ago
Structural and functional analyses of a brain-enriched serotonin receptor, 5-HT1AR, elucidate the...
A single-nucleus transcriptomic atlas of the adult Aedes aegypti mosquito
1 day ago
A comprehensive single-nucleus RNA-seq atlas of >367,000 nuclei from male and female...
Mapping chromatin structure at base-pair resolution unveils a unified model of cis-regulatory element interactions
1 day ago
Li et al. apply base-pair resolution Micro Capture-C ultra to map chromatin...
Structural basis for the concurrence of template recycling and RNA capping in SARS-CoV-2
1 day ago
Structures of the SARS-CoV-2 replication-transcription complex in the pre- and post-capping initiation...
Innate immune and metabolic signals induce mitochondria-dependent membrane lysis via mitoxyperiosis
1 day ago
Wang et al. identify a new lytic cell death pathway, mitoxyperilysis, triggered...
Generation of antigen-specific paired-chain antibodies using large language models
1 day ago
MAGE is a sequence-based protein language model designed to generate diverse human...
Disparate leukemia mutations converge on nuclear phase-separated condensates
1 day ago
Mutant NPM1 and various leukemia oncofusions form biophysically indistingishable nuclear condensates, termed...