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Last updated 9 days ago
The BMP Inhibitor Coco Reactivates Breast Cancer Cells at Lung Metastatic Sites
9 days ago
(Cell 150, 764–779; August 17, 2012)
Dynamics of natural selection preceding human viral epidemics and pandemics
9 days ago
Phylogenetic-based selection analysis of viral evolution before and after spillover reveals that...
Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia
9 days ago
(Cell 182, 1156–1169.e1–e7; September 3, 2020)
Complete biosynthesis of nicotine
9 days ago
Glycosylation and deglycosylation complete nicotine biosynthesis by enabling stereoselective condensation of its...
Deltaviruses spread through a viral Trojan Horse
9 days ago
McKellar et al. have discovered that some satellite viruses act as the...
Microbiome-produced nicotinic acid controls colon regional identity and injury susceptibility
9 days ago
The gut epithelium is regionally patterned to support digestive functions. In the...
High-resolution in situ structures of hantavirus glycoprotein tetramers
9 days ago
The cryo-EM structures of Andes hantavirus (ANDV) glycoprotein tetramers, dimers of tetramers...
Selective targeting of endothelial and perivascular angiocrine ROCK2 treats liver fibrosis
9 days ago
ROCK2 upregulation in endothelial and perivascular cells triggers fibrogenic vascular dysfunction in...
Citrate clearance is a major function of aconitase 2 in the canonical TCA cycle
9 days ago
Beyond its traditional role in supporting bioenergetic and biosynthetic demands, the canonical...
Vitamin B2 and B3 nutrigenomics reveals a therapy for NAXD disease
9 days ago
A nutrigenomics framework identifies genetic diseases amenable to vitamin B2 and B3...
NAD+ hydrolysis catalyzed by SelO is required for mitochondrial homeostasis
9 days ago
SelO, a conserved mitochondrial enzyme, hydrolyzes NAD+ in response to elevated matrix...
Mechanism-guided identification of antidepressant G protein-coupled receptor drug targets
9 days ago
Uncovering ketamine’s rapid antidepressant effects via somatostatin-expressing interneurons in the prefrontal cortex...