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Cell Stem Cell
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Latest posts
Last updated 22 days ago
Quantitative molecular cartography of emergency myelopoiesis reveals conserved modules of hematopoietic activation
22 days ago
Swann et al. conducted a comparative analysis of single-cell RNA-sequencing data from...
Psychological stress drives aging-like hematopoietic stem cell dysfunction through a brain-gut-bone marrow axis
22 days ago
Zhao and colleagues show that psychological stress impairs hematopoietic stem cell function...
ZNF512B safeguards genome integrity at regulatory regions to repress the SASP and inflammation
22 days ago
Belmonte and colleagues show that ZNF512B safeguards genome integrity by directing DNA...
Generation of human appetite-regulating neurons and tanycytes from pluripotent stem cells
22 days ago
Abay-Nørgaard, Mueller, Hänninen, et al. generate cultures of the hypothalamic arcuate nucleus...
Human retinal organoids functionally bridge a transected optic nerve in a rat model
22 days ago
Gong and colleagues demonstrate that transplanting retinal organoids into a completely transected...
Human amygdala-like telencephalic organoids model stress circuitry in assembloid systems
22 days ago
Yang and colleagues generated human amygdala-like telencephalic organoids (hATOs) and amygdala-hypothalamic (hATO-hypoTO)...
Paired pre- and post-transplant human immunoprofiling identifies an IFN-γ-JAK1 axis limiting stem-cell-derived RPE engraftment
22 days ago
Gao et al. identify a Th1-biased, IFN-γ-rich immune state that reprograms hESC-RPE...
ENPP1 blockade with a humanized monoclonal antibody enhances renal repair after acute kidney injury
22 days ago
Deb and colleagues identify ENPP1 as a critical negative regulator of kidney...
Autologous macrophage therapy increases transplant-free survival in cirrhosis: Long-term follow-up of a phase 2 clinical trial
22 days ago
Brennan and Kilpatrick et al. report long-term outcomes in patients with cirrhosis...
Designing complex organoids through developmental principles
22 days ago
Brassard and Wells discuss how next-generation human pluripotent stem cell-derived organoids are...
Evolving strategies for lineage tracing: Genetic markers, synthetic barcodes, and natural variants
22 days ago
This review synthesizes three pillars of lineage tracing—genetic markers, synthetic barcodes, and...
Human stem cell-based embryo model governance: Insights from Japan
22 days ago
Despite rapid advances in human stem cell-based embryo model (SCBEM) research, national...