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Last updated about 16 hours ago
Hepatocyte metabolic adaptations during pregnancy and lactation
about 16 hours ago
Single-cell transcriptomic analysis reveals the hepatocyte metabolic plasticity during pregnancy and lactation...
Stereo-seq V2: Spatial mapping of total RNA on FFPE sections with high resolution
about 16 hours ago
Stereo-seq V2 facilitates single-cell-resolution spatial RNA mapping in FFPE samples through random...
Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation
1 day ago
Development of LOV-domain-controlled ligase for translation localization (LOCL-TL), an optogenetic approach for...
A split-site E3 ligase mechanism enables ZNFX1 to ubiquitinate and cluster single-stranded RNA into ubiquitin-coated nucleoprotein particles
1 day ago
Grabarczyk et al. show the structure and mechanism of a non-canonical ubiquitin...
Tumor transcriptome-wide expression classifiers predict treatment sensitivity in advanced prostate cancers
2 days ago
Large-scale analysis of phase 3 trial samples reveals novel biomarker-treatment pairings to...
Structural basis of poxvirus fusion regulation and anti-A16/G9 antibody-mediated neutralization and protection
3 days ago
Since 2022, several strains of the monkeypox virus adapted to human-to-human transmission...
Human monoclonal antibodies targeting A35 protect from death caused by mpox
3 days ago
Three potent mAbs against the conserved MPXV A35 protein block viral spread...
Mitochondrial activity tunes nociceptor resilience to excitotoxicity
3 days ago
Excitation enables neuronal function; however, overexcitation and calcium overload can be deadly...
Structurally conserved human anti-A35 antibodies protect mice and macaques from mpox virus infection
3 days ago
Administration of human monoclonal antibodies against the MPXV A35 protein mitigate the...
Molecular impact of antisense oligonucleotide therapy in C9orf72-associated ALS
3 days ago
This study provides an in-depth examination of the effects of BIIB078 antisense...
Uncovering phenotypic inheritance from single cells with Microcolony-seq
3 days ago
Microcolony-seq systematically uncovers inherited phenotypic diversity directly from infected human samples, revealing...
Extensive cross-species transmission of pathogens and antibiotic resistance genes in mammals neglected by public health surveillance
3 days ago
Microbiome and virome sequencing of non-traditional farmed and wild mammals reveal an...