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Latest posts
Last updated about 15 hours ago
Advancing cancer detection and treatment using longitudinal routine clinical data
about 15 hours ago
Liu et al. develop Oncoformer, a multimodal transformer that reads routine laboratory...
UniPert-G2CP bridges genetic and chemical screens from molecular representation to phenotype modeling
3 days ago
UniPert-G2CP is an AI framework for jointly modeling molecular-level perturbation causes with...
Dynamic dimer-of-dimers architecture defines Mg2+ transport in human CNNM4
4 days ago
Cryoelectron microscopy structures of human CNNM4 in distinct conformational states reveal how...
Trichoderma swollenin activates AtABCB5-dependent auxin efflux to promote plant development
5 days ago
The beneficial fungus Trichoderma acts through the secreted swollenin ThSWO, which crosses...
An Oryza orphan gene confers trans-species drought tolerance
5 days ago
ROAD1 is an Oryza-specific orphan gene that co-opts conserved ABA signaling to...
The intrinsic cardiac nervous system is essential for cardiac function and survival
6 days ago
Two genetically distinct neuronal subtypes in the intrinsic cardiac nervous system are...
Condensates of the chromatin regulator ANKRD11 restrict hypertranscribed genes to safeguard development
6 days ago
ANKRD11 restricts hypertranscribed genes by forming biomolecular condensates that spatially sequester elongation...
Expanding the scope of protein language modeling to protein-protein interactions with MSA Pairformer
7 days ago
Protein language models have excelled at modeling individual proteins, but extending these...
CSF clearance through arachnoid fenestrations to olfactory meningeal lymphatics
7 days ago
Cerebrospinal fluid (CSF) crosses arachnoid fenestrations near the olfactory bulbs to reach...
Localized PD-1 CAR T therapy reprograms neuroinflammation
7 days ago
PD-1+ T follicular helper-like cells drive B cell-associated pathology in multiple sclerosis...
A domestication-selected enhancer coordinates source-sink balance to improve harvest index and yield in maize
7 days ago
A teosinte-derived enhancer boosts the harvest index and grain yield in maize...
Viral protease-initiated lytic cell death as a universal antiviral mRNA therapy
8 days ago
VIDA mRNA enables universal broad-spectrum antiviral therapy by triggering viral protease-initiated lytic...