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Last updated about 13 hours ago

HLA export by melanoma cells decoys cytotoxic T cells to promote immune evasion

about 13 hours ago

Melanoma cells escape immune surveillance by releasing MHC-antigen-loaded large EVs, known as...

Multimodal AI generates virtual population for tumor microenvironment modeling

7 days ago

GigaTIME leverages multimodal AI to generate virtual multiplex immunofluorescence (mIF) profiles from...

Sensitized mast cells for targeted drug delivery and augmented cancer immunotherapy

7 days ago

IgE-sensitized mast cells loaded with anticancer drugs target antigen-positive tumors, releasing therapeutics...

Structural basis of microtubule-mediated signal transduction

8 days ago

This study presents a structural basis for understanding how microtubules can act...

Biomaterial-minimalistic photoactivated bioprinting of cell-dense tissues

8 days ago

We developed a bioprinting strategy that turns living cells into cell-only bioinks...

Psilocybin triggers an activity-dependent rewiring of large-scale cortical networks

11 days ago

Psilocybin reshapes brain networks through activity-dependent plasticity, including a weakening of recurrent...

Autoantibody-triggered podocyte membrane budding drives autoimmune kidney disease

12 days ago

Kidney podocytes of the blood-urine filter form autoimmunoglobulin-triggered extracellular vesicles (AIT-EVs) for...

Renal PIEZO2 is an essential regulator of renin

12 days ago

The force-sensing ion channel PIEZO2 is an essential regulator of the renin-angiotensin-aldosterone...

A fin-loop-like structure in GPX4 underlies neuroprotection from ferroptosis

12 days ago

A fin-like structural loop in GPX4 is critical for anchoring the enzyme...

Fertilization triggers early proteomic symmetry breaking in mammalian embryos

13 days ago

Single-cell proteomics finds asymmetries between sister blastomeres from the 2-cell stage in...

The effect of shingles vaccination at different stages of the dementia disease course

14 days ago

A natural experiment found that herpes zoster vaccination reduced the occurrence of...