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Latest posts
Last updated 1 day ago
Design principles of cell-state-specific enhancers in hematopoiesis
1 day ago
Screen of minimalistic enhancers in blood progenitor cells demonstrates widespread dual activator-repressor...
Cyclic-dinucleotide-induced filamentous assembly of phospholipases governs broad CBASS immunity
1 day ago
Phospholipase effectors of the CBASS system assemble from an inactive dimeric state...
The recency and geographical origins of the bat viruses ancestral to SARS-CoV and SARS-CoV-2
2 days ago
Recombination-aware evolutionary analyses of the entire genomes of SARS-CoV-1-like and SARS-CoV-2-like viruses...
The structure of human sweetness
2 days ago
A single taste receptor initiates our reactions to both sugars and artificial...
Global genetic diversity of human gut microbiome species is related to geographic location and host health
3 days ago
32,152 gut metagenomes were analyzed, revealing strain-level geographic patterns shaped by horizontal...
m6A alters ribosome dynamics to initiate mRNA degradation
4 days ago
m6A is a potent inducer of ribosome stalling and collisions that trigger...
Tracing the evolutionary history of the CCR5delta32 deletion via ancient and modern genomes
4 days ago
The CCR5delta32 deletion arose on a pre-existing haplotype of 84 variants over...
Genomes of critically endangered saola are shaped by population structure and purging
4 days ago
The generation of whole-genome sequencing data from 26 saolas provides insights into...
Long-term histone lactylation connects metabolic and epigenetic rewiring in innate immune memory
7 days ago
Lactate production in innate immune cells can regulate both acute and long-term...
Snake venom protection by a cocktail of varespladib and broadly neutralizing human antibodies
7 days ago
To combat snake bites from diverse species, this work identifies broadly neutralizing...
Neural-activity-regulated and glia-mediated control of brain lymphatic development
9 days ago
Specialized radial astrocytes govern the development of meningeal mural lymphatic endothelial cells...
A natural gene on-off system confers field thermotolerance for grain quality and yield in rice
9 days ago
A natural variation in QT12, a negative regulator of field thermotolerance controlled...