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Last updated 3 days ago
Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers
3 days ago
Nature Genetics, Published online: 04 July 2025; doi:10.1038/s41588-025-02221-2The paralogs cytidine diphosphate diacylglycerol...
The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types
3 days ago
Nature Genetics, Published online: 04 July 2025; doi:10.1038/s41588-025-02222-1This study employs a functional...
Detecting and quantifying clonal selection in somatic stem cells
4 days ago
Nature Genetics, Published online: 03 July 2025; doi:10.1038/s41588-025-02217-ySCIFER detects clonal selection in...
Spatial organization of chromatin restricts activation of poised alternative promoters in LTRs
4 days ago
Nature Genetics, Published online: 03 July 2025; doi:10.1038/s41588-025-02238-7Transposable elements (TEs) are important...
Single-cell Micro-C profiles 3D genome structures at high resolution and characterizes multi-enhancer hubs
5 days ago
Nature Genetics, Published online: 02 July 2025; doi:10.1038/s41588-025-02247-6scMicro-C is a new method...
The long-term effects of chemotherapy on normal blood cells
6 days ago
Nature Genetics, Published online: 01 July 2025; doi:10.1038/s41588-025-02234-xMutational signature analysis of blood...
Clonal evolution of hematopoietic stem cells after autologous stem cell transplantation
6 days ago
Nature Genetics, Published online: 01 July 2025; doi:10.1038/s41588-025-02235-wAnalysis of whole-genome sequencing data...
How chemotherapy shapes hematopoietic stem cells
6 days ago
Nature Genetics, Published online: 01 July 2025; doi:10.1038/s41588-025-02231-0Two complementary studies used whole-genome...
Disruption of TAD hierarchy promotes LTR co-option in cancer
7 days ago
Nature Genetics, Published online: 30 June 2025; doi:10.1038/s41588-025-02239-6NIPBL perturbation activates long terminal...
Tumor aneuploidy as a prognostic and predictive biomarker in immune checkpoint blockade
7 days ago
Nature Genetics, Published online: 30 June 2025; doi:10.1038/s41588-025-02226-xAneuploidy, a defining feature of...
Author Correction: Incorporating genetic data improves target trial emulations and informs the use of polygenic scores in randomized controlled trial design
10 days ago
Nature Genetics, Published online: 27 June 2025; doi:10.1038/s41588-025-02275-2Author Correction: Incorporating genetic data...
How and when organisms edit their own genomes
10 days ago
Nature Genetics, Published online: 27 June 2025; doi:10.1038/s41588-025-02230-1This Review describes the changes...