eLife

Structural mechanisms of pump assembly and drug transport in the AcrAB–TolC efflux system

about 19 hours ago

Tripartite multidrug efflux pumps that span the cell envelope are essential for...

How individual vigor shapes human–human physical interaction

about 19 hours ago

The speed of voluntary movements varies systematically, with some individuals moving consistently...

Dimorphic neural network architecture prioritizes sexual-related behaviors in male Caenorhabditis elegans

about 19 hours ago

Neural network architecture determines its functional output. However, the detailed mechanisms are...

The robust, high-throughput, and temporally regulated roxCre and loxCre reporting systems for genetic modifications in vivo

about 19 hours ago

Cre-loxP technology, a cornerstone in fate mapping and in vivo gene function...

Taking the biology seriously makes models better

about 19 hours ago

A new biologically-informed training paradigm enables protein language models to predict affinity...

Alpha-band phase modulates perceptual sensitivity by changing internal noise and sensory tuning

about 19 hours ago

Alpha-band neural oscillations (8–13 Hz) are theorized to phasically inhibit visual processing...

Fragmentation and aggregation of cyanobacterial colonies

4 days ago

Fluid flow has a major effect on the aggregation and fragmentation of...

Cdhr1a and pcdh15b may link photoreceptor outer segments with calyceal processes revealing a potential mechanism for cone-rod dystrophy

4 days ago

Cone-rod dystrophy (CRD) is a macular degeneration disorder characterized by initial cone...

Correction: Autologous P63+ lung progenitor cell transplantation in idiopathic pulmonary fibrosis: a phase 1 clinical trial

4 days ago

Uncovering shared and tissue-specific molecular adaptations to intermittent fasting in liver, brain, and muscle

4 days ago

Intermittent fasting (IF) has emerged as a powerful dietary intervention with profound...

Modality-agnostic decoding of vision and language from fMRI

4 days ago

Humans perform tasks involving the manipulation of inputs regardless of how these...

PTEN restrains SHH medulloblastoma growth through cell autonomous and nonautonomous mechanisms

4 days ago

A third of patients with the pediatric cerebellar tumor Medulloblastoma (MB) have...