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Last updated about 12 hours ago
Adapting clinical chemistry plasma as a source for liquid biopsies
1 day ago
Circulating cell-free DNA (cfDNA) is valuable for molecular testing, but typically requires...
RadD from Fusobacterium nucleatum engages NKp46 to promote antitumor cytotoxicity
1 day ago
Fusobacterium nucleatum, a gram-negative bacterium implicated in periodontal disease, contributes to tumor...
Evidence of off-target probe binding affecting 10x Genomics Xenium gene panels compromise accuracy of spatial transcriptomic profiling
1 day ago
The accuracy of spatial gene expression profiles generated by probe-based in situ...
Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice
2 days ago
mRNA vaccines emerged as a leading vaccine technology during the COVID-19 pandemic...
The FAM53C/DYRK1A axis regulates the G1/S transition of the cell cycle
2 days ago
A growing number of therapies are being developed to target the cell...
Prickle and Ror modulate Dishevelled-Vangl interaction to regulate non-canonical Wnt signaling during convergent extension in Xenopus
2 days ago
Convergent extension (CE) is a fundamental morphogenetic process where oriented cell behaviors...
Towards a unified molecular mechanism for ligand-dependent activation of NR4A-RXR heterodimers
2 days ago
A subset of nuclear receptors (NRs) function as permissive heterodimers with retinoid...
The sound of neural silence
2 days ago
A new fluorescent sensor makes it possible to track the neurotransmitter GABA...
Unbend, correction of local beam-induced sample motion in cryo-EM images using a 3D spline model
2 days ago
The exposure of frozen biological samples to the high-energy electron beam in...
On-demand seizures facilitate rapid screening of therapeutics for epilepsy
2 days ago
Animal models of epilepsy are critical in drug development and therapeutic testing...
Inference of germinal center evolutionary dynamics via simulation-based deep learning
4 days ago
B cells and the antibodies they produce are vital to health and...
Interrogating the structure and function of the human voltage-gated proton channel (hHv1) with a fluorescent noncanonical amino acid
4 days ago
The human voltage-gated proton channel (hHv1) is a dimer of voltage-sensor domains...