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Latest posts
Last updated 1 day ago
Glycocalyx-edited mesenchymal stem/stromal cell therapy in advanced osteoporosis
1 day ago
Mesenchymal stem/stromal cell (MSC)-based therapy holds promise for reversal of bone loss...
Mitochondrial ATP promotes T cell differentiation through chromatin accessibility
1 day ago
Cell-mediated immunity requires cytotoxic CD8+ T cells that adopt and maintain an...
Metax enables accurate cross-domain taxonomic profiling of metagenomes
1 day ago
Metax is a cross-domain metagenomic profiler that uses genome-wide coverage evidence to...
Architecture of the serotonergic projectome in the mouse brain
2 days ago
Serotonin neurons innervate nearly the entire mammalian brain, yet how their projections...
4D spatiotemporal landscape of mitochondrial phenotypes across cellular states unlocked through representation learning
2 days ago
Agarwal et al. introduce MitoSpace, a self-supervised model trained on 4D lattice...
Caloric restriction modulates genome-wide somatic mutation in mice
3 days ago
Mutations accumulate in cells with age, while caloric restriction extends lifespan across...
Structural basis of a SWI/SNF-associated transcription pre-initiation complex
4 days ago
Cryo-EM and genetic analyses reveal that the SWI/SNF chromatin remodeler is an...
Identification of the tendon/ligament stem cell in mice and humans
5 days ago
The tendon/ligament stem cell is identified, and dysregulation of differentiation in this...
Tabula Sapiens 2.0: A comprehensive transcriptomic atlas of human cell types
10 days ago
An expanded atlas of human cells maps the expression of nearly all...
Live-cell transcriptomics with engineered virus-like particles
11 days ago
Najia, Le, Borrajo et al. establish “cellular self-reporting,” a technology to export...
Cross-species single-cell atlas of the striatum defines cell-type and subregion disease vulnerabilities
11 days ago
Single-nucleus RNA sequencing and spatial validation across human and mouse striatum define...
De novo pan-rhodamine binders for fluorescence microscopy from mammalian cells to extremophiles
11 days ago
We developed an AI-based and principled computational strategy for de novo design...