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Nature Genetics

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Last updated about 21 hours ago

Germline genetic variation impacts clonal hematopoiesis landscape and progression to malignancy

about 21 hours ago

Nature Genetics, Published online: 15 July 2025; doi:10.1038/s41588-025-02250-xThe relationship between pathogenic germline...

Enhancer mutational screen in vivo

5 days ago

Nature Genetics, Published online: 11 July 2025; doi:10.1038/s41588-025-02277-0Enhancer mutational screen in vivo

Y chromosome loss in cancer

5 days ago

Nature Genetics, Published online: 11 July 2025; doi:10.1038/s41588-025-02276-1Y chromosome loss in cancer

Expanding in situ genome sequencing

5 days ago

Nature Genetics, Published online: 11 July 2025; doi:10.1038/s41588-025-02278-zExpanding in situ genome sequencing

Perturb-Multimodal pooled screening in intact tissues

5 days ago

Nature Genetics, Published online: 11 July 2025; doi:10.1038/s41588-025-02279-yPerturb-Multimodal pooled screening in intact...

Enhancer adoption by an LTR retrotransposon generates viral-like particles, causing developmental limb phenotypes

7 days ago

Nature Genetics, Published online: 09 July 2025; doi:10.1038/s41588-025-02248-5Activation of an LTR retrotransposon...

Decomposition of phenotypic heterogeneity in autism reveals underlying genetic programs

7 days ago

Nature Genetics, Published online: 09 July 2025; doi:10.1038/s41588-025-02224-zClasses of autism are uncovered...

A retrotransposon caught red-handed in a curious case of missing digits

7 days ago

Nature Genetics, Published online: 09 July 2025; doi:10.1038/s41588-025-02147-9A newly uncovered mechanism shows...

Cytidine diphosphate diacylglycerol synthase 2 is a synthetic lethal target in mesenchymal-like cancers

12 days ago

Nature Genetics, Published online: 04 July 2025; doi:10.1038/s41588-025-02221-2The paralogs cytidine diphosphate diacylglycerol...

The synthetic lethal interaction between CDS1 and CDS2 is a vulnerability in uveal melanoma and across multiple tumor types

12 days ago

Nature Genetics, Published online: 04 July 2025; doi:10.1038/s41588-025-02222-1This study employs a functional...

Detecting and quantifying clonal selection in somatic stem cells

13 days ago

Nature Genetics, Published online: 03 July 2025; doi:10.1038/s41588-025-02217-ySCIFER detects clonal selection in...

Spatial organization of chromatin restricts activation of poised alternative promoters in LTRs

13 days ago

Nature Genetics, Published online: 03 July 2025; doi:10.1038/s41588-025-02238-7Transposable elements (TEs) are important...