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Gut microbiota–derived metabolite drives atherosclerosis

1 day ago

Nature Reviews Drug Discovery, Published online: 27 August 2025; doi:10.1038/d41573-025-00141-8Gut microbiota–derived metabolite...

Transport vehicle delivers antibodies to the brain

1 day ago

Nature Reviews Drug Discovery, Published online: 27 August 2025; doi:10.1038/d41573-025-00140-9Transport vehicle delivers...

From gene hunter to drug hunter

15 days ago

Nature Reviews Drug Discovery, Published online: 14 August 2025; doi:10.1038/d41573-025-00139-2Howard Chang, Amgen’s...

Neutrophil-targeted drug secures first FDA approval for inflammatory lung disease

16 days ago

Nature Reviews Drug Discovery, Published online: 12 August 2025; doi:10.1038/d41573-025-00135-6Neutrophil-targeted drug secures...

Small-molecule PI3Kα binder with selective anticancer activity

21 days ago

Nature Reviews Drug Discovery, Published online: 07 August 2025; doi:10.1038/d41573-025-00136-5Small-molecule PI3Kα binder...

Leading orexin receptor agonist clears phase III for narcolepsy

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Nature Reviews Drug Discovery, Published online: 07 August 2025; doi:10.1038/d41573-025-00137-4Leading orexin receptor...

FDA grants first US approval for decades-old eye drug

21 days ago

Nature Reviews Drug Discovery, Published online: 07 August 2025; doi:10.1038/d41573-025-00138-3FDA grants first...

In vivo engineering broadens CAR-T cell therapy use

23 days ago

Nature Reviews Drug Discovery, Published online: 05 August 2025; doi:10.1038/d41573-025-00134-7In vivo engineering...

How multispecific molecules are transforming pharmacotherapy

27 days ago

Nature Reviews Drug Discovery, Published online: 01 August 2025; doi:10.1038/s41573-025-01262-wMultispecific drugs are...

Trends in the development of cellular and gene therapy in China

28 days ago

Nature Reviews Drug Discovery, Published online: 31 July 2025; doi:10.1038/d41573-025-00126-7Trends in the...

Broader horizons for cereblon glue degraders

29 days ago

Nature Reviews Drug Discovery, Published online: 31 July 2025; doi:10.1038/d41573-025-00133-8Broader horizons for...

Oncolytic virus drought continues, as Replimune fails to secure FDA cancer approval

29 days ago

Nature Reviews Drug Discovery, Published online: 30 July 2025; doi:10.1038/d41573-025-00132-9Oncolytic virus drought...