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Last updated about 13 hours ago
Hinge modifier approach opens door to drugging HECT E3 ligases
about 13 hours ago
Nature Reviews Drug Discovery, Published online: 09 May 2025; doi:10.1038/d41573-025-00084-0Hinge modifier approach...
A liver-directed route to reverse allergies
1 day ago
Nature Reviews Drug Discovery, Published online: 08 May 2025; doi:10.1038/d41573-025-00083-1A liver-directed route...
FDA approves J&J’s FcRN blocker for generalized myasthenia gravis
2 days ago
Nature Reviews Drug Discovery, Published online: 07 May 2025; doi:10.1038/d41573-025-00081-3FDA approves J&J’s...
FDA approves cell-sheet-based gene therapy for severe skin disease
2 days ago
Nature Reviews Drug Discovery, Published online: 07 May 2025; doi:10.1038/d41573-025-00082-2FDA approves cell-sheet-based...
Application of new approach methodologies for nonclinical safety assessment of drug candidates
7 days ago
Nature Reviews Drug Discovery, Published online: 02 May 2025; doi:10.1038/s41573-025-01182-9New approach methodologies...
Ramping up mitochondrial DNA replication
7 days ago
Nature Reviews Drug Discovery, Published online: 02 May 2025; doi:10.1038/d41573-025-00079-xRamping up mitochondrial...
TIM-3 regulates microglial function
8 days ago
Nature Reviews Drug Discovery, Published online: 02 May 2025; doi:10.1038/d41573-025-00078-yTIM-3 regulates microglial...
Understanding LAG3 immune checkpoint function
8 days ago
Nature Reviews Drug Discovery, Published online: 02 May 2025; doi:10.1038/d41573-025-00076-0Understanding LAG3 immune...
Targeting RNA structure to treat prostate cancer
8 days ago
Nature Reviews Drug Discovery, Published online: 02 May 2025; doi:10.1038/d41573-025-00077-zTargeting RNA structure...
Lasso peptide targets drug-resistant bacteria
8 days ago
Nature Reviews Drug Discovery, Published online: 02 May 2025; doi:10.1038/d41573-025-00075-1Lasso peptide targets...
GLP-1-based therapies for diabetes, obesity and beyond
14 days ago
Nature Reviews Drug Discovery, Published online: 25 April 2025; doi:10.1038/s41573-025-01183-8GLP-1-based therapies represent...
New antifungal tackles drug-resistant infections
16 days ago
Nature Reviews Drug Discovery, Published online: 24 April 2025; doi:10.1038/d41573-025-00074-2New antifungal tackles...