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Last updated 3 days ago

Betting on β-catenin inhibitors in oncology

3 days ago

Nature Reviews Drug Discovery, Published online: 12 December 2025; doi:10.1038/d41573-025-00206-8The WNT–β-catenin pathway...

Calico, Alphabet’s anti-ageing play, goes it alone

3 days ago

Nature Reviews Drug Discovery, Published online: 12 December 2025; doi:10.1038/d41573-025-00205-9Philip Kym, Calico’s...

Top product forecasts for 2026

5 days ago

Nature Reviews Drug Discovery, Published online: 10 December 2025; doi:10.1038/d41573-025-00203-xTop product forecasts...

Upcoming FDA approval decisions in Q1 2026

5 days ago

Nature Reviews Drug Discovery, Published online: 10 December 2025; doi:10.1038/d41573-025-00204-wUpcoming FDA approval...

First-in-class APRIL inhibitor secures approval for rare kidney disease

10 days ago

Nature Reviews Drug Discovery, Published online: 05 December 2025; doi:10.1038/d41573-025-00202-yFirst-in-class APRIL inhibitor...

Pathway-selective 5-HT1AR agonist speeds up antidepressant effect

12 days ago

Nature Reviews Drug Discovery, Published online: 04 December 2025; doi:10.1038/d41573-025-00201-zPathway-selective 5-HT1AR agonist...

Stimulating medicines repurposing in the EU: a pilot project

12 days ago

Nature Reviews Drug Discovery, Published online: 03 December 2025; doi:10.1038/d41573-025-00198-5Stimulating medicines repurposing...

Omics with active learning optimizes phenotypic screens

14 days ago

Nature Reviews Drug Discovery, Published online: 02 December 2025; doi:10.1038/d41573-025-00200-0Omics with active...

Novel antimalarial passes key phase III test

20 days ago

Nature Reviews Drug Discovery, Published online: 26 November 2025; doi:10.1038/d41573-025-00193-wNovel antimalarial passes...

Enhancing RNA stability

20 days ago

Nature Reviews Drug Discovery, Published online: 25 November 2025; doi:10.1038/d41573-025-00195-8Enhancing RNA stability

Designing G-protein-selective allosteric modulators

20 days ago

Nature Reviews Drug Discovery, Published online: 25 November 2025; doi:10.1038/d41573-025-00197-6Designing G-protein-selective allosteric...

Repairing spinal cord damage

20 days ago

Nature Reviews Drug Discovery, Published online: 25 November 2025; doi:10.1038/d41573-025-00196-7Repairing spinal cord...