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Angewandte Chemie International Edition
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Last updated about 14 hours ago
Marker‐Agnostic Tumor Anchoring Chimeras Enable pH‐Gated Immune Engagement
about 16 hours ago
ABSTRACT Targeted cancer immunotherapies typically depend on cell surface antigens to direct...
Spin‐State Dichotomy of On‐Cycle Cobalt(II) Organometallics Informs Polar Cobalt(0/II) Versus Radical Cobalt(I/II/III) Cross‐Coupling Mechanisms
about 16 hours ago
While metal–aryl intermediates are central to all cross-coupling reactions, for state-of-the-art cobalt-catalyzed...
Combining High‐Throughput Experimentation and Automated Flow for Bayesian Optimization of a Metallaphotoredox Reaction
about 16 hours ago
A two-stage workflow combines plate-based HTE optimization of five discrete reaction parameters...
Benzodithiolane‐Enabled C─O Bond Activation for Deoxygenative Functionalization of Carbohydrates and Nucleosides
1 day ago
A benzodithiolane (BDT) mediated C─O activation platform is introduced that enables deoxygenative...
Thermostable Bioluminescent Intercalating Dyes for Real‐Time, Integrated Nucleic Acid Amplification and Detection
1 day ago
We present a bioluminescent diagnostic platform that integrates DNA amplification and detection...
An Insensitive Energetic Material as a High‐Performance Organic Cathode Toward Dual‐Mode Batteries
1 day ago
TAAT, an insensitive nitrogen-rich energetic molecule, enables dual-mode energy release in lithium...
Cyano‐Triggered Strong Anion‐π Interactions: Unlocking Anion–Cation Adsorption Bifunction
1 day ago
The introduction of electron-withdrawing cyano groups yields an electron-deficient aromatic system that...
Copper‐Catalyzed Enantioselective C–H Phosphorylation Enabled by a 3,3’‐Difluorinated BINOL Ligand
1 day ago
An unprecedented copper-catalyzed enantioselective C–H/P–H oxidative coupling reactions was accomplished, employing easily...
Computer Vision Enables Monitoring and Kinetic Analysis of Structurally Diverse Carbon Monoxide Surrogates
1 day ago
A non-contact computer vision method enables monitoring and quantitative comparison of vessel-specific...
Diastereomeric Configuration Modulates Liquid–Liquid Phase Separation and Catalysis in Minimalist Dipeptide Coacervates
1 day ago
EnA set of stereoisomeric dipeptides composed of proline (P) and naphthylalanine (Nal)...
Linker Nitrogen Tunes Charge Polarity to Strengthen Built‐In Electric Fields in Covalent Organic Frameworks for Photocatalytic Oxidation
1 day ago
Linker nitrogen engineering provides a chemically countable electrostatic handle in porphyrinic COFs...