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Angewandte Chemie International Edition

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Last updated about 12 hours ago

Targeting the Membrane‐Embedded Rhomboid Protease GlpG: A Multimodal Strategy for Inhibitor Discovery and Mechanistic Insight

about 16 hours ago

Created in BioRender. Bohg, C. (2026) https://BioRender.Com/ vi9hi4f Rhomboid proteases are a...

Proton‐Activated Artificial Channels for pH‐Selective Cancer Therapy

about 16 hours ago

A novel class of proton-activated artificial ion channels was developed by integrating...

Modulation of Local Hydrogen Bonding for Highly Efficient Bi‐MOFs Photocatalyzed Fixation of N2 in Aqueous Solution

about 16 hours ago

Light-induced modulation of the local microenvironment on the surface of Bi-MOF enhances...

Simultaneous Boost of SF6 Adsorption Capacity and Kinetics Through Isoreticular Functionalization of Zinc(II)‐Pyrazolate Frameworks

about 16 hours ago

Isoreticular functionalization of a metal-organic framework (MOF) with a pyridine unit unlocks...

Inert Complexes Unlock Ligand‐Accelerated Transition‐Metal Catalysis on Proteins

about 16 hours ago

Ligand-accelerated transition-metal catalysis on proteins is achieved by stabilizing metal–ligand complexes against...

Dynamic Iodide Regeneration Enabled by Piperazine‐Tailored PCBM Interfaces for Photothermally Stable and Efficient Inverted Perovskite Photovoltaics

about 16 hours ago

We report a new class of PA-tailored fullerene derivative, PCBM-PA, that uniquely...

Highly Efficient Deep‐Blue Room‐Temperature Phosphorescence With Tunable Long‐Lived Afterglow and Reversible Photoactivation Behavior

about 17 hours ago

The introduction of succinimide units into the triphenylamine skeleton enables n-π* transition...

Covalent Protein Inhibitors via Tyrosine and Tryptophan Conjugation with Cyclic Imine Mannich Electrophiles

about 17 hours ago

Targeted covalent inhibitors (TCI) containing cyclic imine warheads react with tyrosine and...

Rapid RASER MRI

about 17 hours ago

Rapid RASER MRI allows for image acquisition without RF excitation. Instead, a...

Zinc‐Complex Orchestrating Pyroptosis for Hypoxia‐Tolerant Photoimmunotherapy

about 17 hours ago

A novel Zn2+-complex was developed for orchestrating hypoxia-tolerant photoimmunotherapy. Zn2+ coordination significantly...

PCA‐Based Database Mining Enables the Discovery of Bacterial Carbene Transferases for Stereodivergent Cyclopropanation

about 17 hours ago

Database mining using principal component analysis (PCA)-based clustering enabled discovery of bacterial...

An Iridium‐Catalyzed Conia‐ene Reaction for the Diastereo‐ and Enantioselective Synthesis of Complex Ring Systems

about 17 hours ago

Iridium-catalyzed Conia-ene reactions of α-amino amides are described. This provides a versatile...