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Angewandte Chemie International Edition

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Iridium‐Catalyzed Ionic Hydrogenation of Multi‐Aza Heterocycles

1 day ago

Saturated nitrogen-containing heterocycles are ubiquitous in bioactive molecules and are thus attractive...

Isosteric Engineering of Enzymes: Overcoming Activity–Stability Trade‐Offs by Site‐Selective CH → N Substitutions

1 day ago

Coupling biosynthetic noncanonical amino acid production with genetic code expansion enables site-specific...

Peptide‐Functionalized Hydroxypropyl Cellulose Mitigates Amyloid‐β Protein Induced Endothelial Leakiness and Enhances Cognitive Function in Alzheimer's Disease

1 day ago

The peptide functionalized hydroxypropyl cellulose conjugate (HPC-pet) sequesters Aβ oligomers (Aβo) to...

Chemoenzymatic Synthesis of Heparan Sulfate Oligosaccharides by a Covalent Catch‐and‐Release Approach

1 day ago

A glycan having a hydrazide tag enables chemoenzymatic synthesis of HS oligosaccharides...

Rational Tailoring of Hole‐Selective Self‐Assembly Monolayers Based on Sulfur‐Containing Heterocycles for High‐Performance Perovskite Solar Cells

1 day ago

This molecular engineering strategy introduces non-centrosymmetric self-assembled monolayers (SAMs), TP and BTP...

Chemoenzymatic Synthesis of Well‐Defined α(2,8)‐ and α(2,9)‐Linked Oligosialosides

1 day ago

Well-defined α(2,8)- and α(2,9)-linked oligosialic acids of different lengths can be prepared...

Interfacial Lewis Acid Chemistry Enabled by Mesoporous MOFs Toward High‐Performance Four‐Electron Zinc–Iodine Batteries

1 day ago

Here, we establish an interfacial Lewis acid chemistry based on mesoporous Zr-UiO-66...

Active Oxygenated Group‐Rich Polymer Electrolyte Synchronizing Bilateral Interfacial Stabilization and Accelerated Kinetics for High‐Performance Solid‐State Li–O2 Batteries

1 day ago

A polymerized glycidyl methacrylate (PGM)-based gel polymer electrolytewith abundant active oxygenated groups(e.g...

Octahedral–Tetrahedral Site Synergism in Spinel Oxides Enables 1700 h‐Stable Electrosynthesis of 2,5‐Furandicarboxylic Acid in Near‐Neutral Media

1 day ago

Asymmetric Ruoct/Nitet coordination in spinel Co3O4 enables cooperative surface hydroxylation and HMF...

Asymmetric Total Synthesis of (+)‐Ineleganolide

1 day ago

The structurally complex cembrane norditerpenoid (+)-ineleganolide has been synthesized by a route...

Unlocking Zn‐Ion Diffusion in Disordered Rocksalt Cathodes for Nonaqueous Zn‐Ion Batteries

1 day ago

Developing viable cathode materials for multivalent battery chemistries is challenging due to...