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Cancer Cell
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Last updated 26 days ago
Reliable detection of Host-Microbe Signatures in cancer using PRISM
26 days ago
Ghaddar et al. develop and benchmark PRISM, a computational framework for precise...
Vascular STING activation facilitates NK cell anti-tumor immunity in small cell lung cancer
26 days ago
Integrating microphysiological and spatial profiling, Campisi et al. identify tumor vasculature as...
Dissecting genetic and immune drivers of heterogeneous responses to neoadjuvant immunochemotherapy in gastric cancer
26 days ago
Zhao et al. delineate genetic and tumor microenvironment shifts of gastric cancer...
A tumor-associated photoreceptor signature unifies distinct central nervous system malignancies
26 days ago
Pineoblastoma is an aggressive childhood brain cancer. Using single-cell transcriptomics of patient...
HS-20093, a B7-H3-targeted antibody-drug conjugate in lung cancer: Results from the ARTEMIS-001 phase 1a/b trial
26 days ago
Wang et al. conducted an open-label, multicenter phase 1a/b study to evaluate...
IFNγ-dependent metabolic reprogramming restrains an immature, pro-metastatic lymphatic state in melanoma
26 days ago
Karakousi et al. uncover a role for IFNγ in regulating tumor-associated lymphatic...
Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma
26 days ago
Abdelfattah et al. uncovers a male-biased dependency on YAP1 for immune evasion...
Knowledge-enhanced pretraining for vision-language pathology foundation model on cancer diagnosis
26 days ago
Zhou et al. develop KEEP, a knowledge-enhanced foundation model that integrates disease...
Lipid oxidation reprogramming in cancer-associated fibroblasts enhances CD8+ T cell cytotoxicity and therapeutic response
26 days ago
Ma et al. identify a chemotherapy-induced PTGER3+ CAF subset with increased lipid...
Reactivating p53 mutants selectively in patients
26 days ago
As the most frequently mutated protein across cancers, the tumor suppressor protein...
Overcoming functional and translational challenges of cellular immunotherapies for solid tumors
26 days ago
Though successful in hematologic cancers, cell therapies face major barriers in solid...
Tumor-restraining fibroblasts emerge after chemotherapy specifically in responders
26 days ago
In this issue of Cancer Cell, Ma et al. identify a neoadjuvant...