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Cancer Cell
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Last updated 28 days ago
Myofibroblast programming blocks differentiation of TLS-organizing fibroblastic reticular cells in pancreatic cancer
28 days ago
Kirschstein et al. discover that TGFβ receptor signaling in myofibroblasts blocks the...
Candida albicans synergizes with Fusobacterium nucleatum in colorectal cancer progression via the Flo9-RadD interaction
28 days ago
How does other types of microbe like fungi influence tumor-promoting role of...
Cancer type-specific variation in patterns of driver alterations across 50,000 tumors
28 days ago
Bandlamudi et al. analyze 54,331 tumors across 448 cancer subtypes to define...
Radiotherapy synergizes with an inducible AAV-based immunotherapy platform to program local and systemic antitumor immunity
28 days ago
Marco et al. demonstrate that radiotherapy epigenetically reprograms AAV episomes to enhance...
JYP0322, a highly selective and brain-penetrant ROS1 inhibitor, overcomes ROS1G2032R resistance mutation in NSCLC: The first-in-human phase 1 trial
28 days ago
Targeted therapies against ROS1-rearrangements cancer face limitations. Ma et al. report that...
Molecular insights into early malignant transition of hepatocellular carcinoma
28 days ago
Zhang et al. present a comprehensive genomic and immunological analysis of the...
The landscape of structural variation in pediatric cancer
28 days ago
Greenhalgh et al. develop a resource of curated structural variants (SVs) from...
Bridging clinical gaps in personalized cancer neoantigen vaccines
28 days ago
Khaddour et al. synthesize emerging data highlighting tumor indications suitable to investigate...
Activated T cell extracellular vesicle DNA transfer enhances antigen presentation and anti-tumor immunity
28 days ago
Hu et al. identify an intercellular communication mechanism by which activated T...
Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia
28 days ago
Shi et al. delineate an interplay among tumor cells, immune cells, and...
Cancer cachexia: A tumor-driven disorder of whole-body homeostasis
28 days ago
Cancer cachexia is a tumor-driven collapse of systemic homeostasis rather than a...
Precancerous niches as gatekeepers of tumor initiation
28 days ago
Clonal competition eliminates most early neoplastic lesions, yet a subset persists and...