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Last updated 25 days ago

Proteogenomic characterization of non-functional pancreatic neuroendocrine tumors unravels clinically relevant subgroups

25 days ago

In this study, Ji et al. conduct comprehensive proteogenomic characterization of non-functional...

Distinct CD8+ T cell dynamics associate with response to neoadjuvant cancer immunotherapies

25 days ago

Li et al. analyze CD8+ T cells collected from HNSCC patients treated...

Effective targeting of PDGFRA-altered high-grade glioma with avapritinib

25 days ago

PDGFRA is commonly altered in pediatric HGG. Mayr et al. report that...

Diet-microbiome interactions in cancer

25 days ago

Abdeen et al. review the complex relationships between diet, microbiome, and cancer...

Fragmentomics profiling and quantification of plasma Epstein-Barr virus DNA enhance prediction of future nasopharyngeal carcinoma

25 days ago

The analysis of fragmentation patterns in plasma DNA (i.e., fragmentomics) is actively...

New horizons at the interface of artificial intelligence and translational cancer research

25 days ago

Yates and Van Allen review the applications of artificial intelligence in multiomics...

CAR-T therapy in solid tumors

25 days ago

Du et al. discuss the obstacles in treating solid tumors by CAR-T...

Turning the kaleidoscope: Innovations shaping the future of clinical trial design

25 days ago

Current clinical trials are based on rigid designs and drug-centric approaches that...

Precision oncology and genetic ancestry: The science behind population-based cancer disparities

25 days ago

Precision oncology has transformed cancer care but has barely benefited patients of...

Navigating established and emerging biomarkers for immune checkpoint inhibitor therapy

25 days ago

Immune checkpoint inhibitors (ICIs) have improved cancer outcomes but only a minority...

Advocating for change—Integration of efforts across the drug discovery and development continuum

25 days ago

In recent decades, we’ve witnessed tremendous advances in oncology with an increase...

Neoadjuvant immune checkpoint therapy: Enabling insights into fundamental human immunology and clinical benefit

25 days ago

Neoadjuvant immune checkpoint therapy (ICT) is revolutionizing cancer treatment and provides critical...