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Latest posts

Last updated about 15 hours ago

RFK Jr. Must Go. And He's Not the Only One.

about 19 hours ago

Our public health and science research agencies have already been ransacked by...

Go Make Me Fifty Kilos of This Stuff

3 days ago

Here's a nice paper that goes into the details of scale-up of...

Lithium Orotate Revisited

4 days ago

After that big lithium-and-Alzheimer’s paper recently, I thought a look at the...

When Do You Need a Macrocycle, Anyway?

7 days ago

One of the trends of the last twenty years or so medicinal...

Cranking Up Protein Expression to the Limit

8 days ago

I found this to be an interesting thought experiment that’s been brought...

Carbamorphine And More

10 days ago

I wrote here years ago about how many natural product scaffolds had...

Kakistocracy

11 days ago

Earlier this month, Patrick Joseph White of Atlanta tried to drive onto...

Journal Impact Nonsense

15 days ago

Here’s a revealing look at the state of the chemistry literature in...

The Frontiers of Structure

16 days ago

Let’s have a look up near the state of the art in...

Lithium Deficiency and Alzheimer's Disease

18 days ago

Let’s talk about this paper, which has made quite a splash. The...

Microglia to the Rescue

21 days ago

Here’s a field that I’ve been meaning to write about, because it’s...

In Praise of Weirdness

22 days ago

Note: this started off (many paragraphs ago) as the intro to a...