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Last updated 1 day ago
Come get dissolved in PML bodies
1 day ago
Nature Chemical Biology, Published online: 01 July 2025; doi:10.1038/s41589-025-01960-xPromyelocytic leukemia (PML) nuclear...
Structure and mechanism of an actin-dependent bacterial phosphoryl AMPylase
3 days ago
Nature Chemical Biology, Published online: 30 June 2025; doi:10.1038/s41589-025-01945-wLegionella effector LnaB, a...
Harnessing computational technologies to facilitate antibody–drug conjugate development
6 days ago
Nature Chemical Biology, Published online: 27 June 2025; doi:10.1038/s41589-025-01950-zThe development of antibody–drug...
The PARP1–EXD2 axis orchestrates R-loop resolution to safeguard genome stability
6 days ago
Nature Chemical Biology, Published online: 27 June 2025; doi:10.1038/s41589-025-01952-xDysregulated R-loops can compromise...
Publisher Correction: Polyvalent folate receptor-targeting chimeras for degradation of membrane proteins
7 days ago
Nature Chemical Biology, Published online: 26 June 2025; doi:10.1038/s41589-025-01976-3Publisher Correction: Polyvalent folate...
Insights into G-protein coupling preference from cryo-EM structures of Gq-bound PTH1R
7 days ago
Nature Chemical Biology, Published online: 26 June 2025; doi:10.1038/s41589-025-01957-6Description of the cryo-EM...
At the roots of resistance
7 days ago
Nature Chemical Biology, Published online: 26 June 2025; doi:10.1038/s41589-025-01937-wThe discovery of seven...
Terminal alkyne formation by a pyridoxal phosphate-dependent enzyme
8 days ago
Nature Chemical Biology, Published online: 25 June 2025; doi:10.1038/s41589-025-01954-9Alkynes found in natural...
A pseudoenzyme enables indole biosynthesis in eudicot plants
8 days ago
Nature Chemical Biology, Published online: 25 June 2025; doi:10.1038/s41589-025-01943-yDespite the importance of...
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
9 days ago
Nature Chemical Biology, Published online: 24 June 2025; doi:10.1038/s41589-025-01936-xHigh-content protein arrays were...
Stick it with VHL
9 days ago
Nature Chemical Biology, Published online: 24 June 2025; doi:10.1038/s41589-025-01897-1Molecular glue degraders are...
A class of benzofuranoindoline-bearing heptacyclic fungal RiPPs with anticancer activities
10 days ago
Nature Chemical Biology, Published online: 23 June 2025; doi:10.1038/s41589-025-01946-9Here the authors report...