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Last updated about 12 hours ago
Enzymatic combinatorial synthesis of E-64 and related cysteine protease inhibitors
about 12 hours ago
Nature Chemical Biology, Published online: 09 May 2025; doi:10.1038/s41589-025-01907-2Liu et al. discover...
Biosurfactant biosynthesis by Alcanivorax borkumensis and its role in oil biodegradation
about 12 hours ago
Nature Chemical Biology, Published online: 09 May 2025; doi:10.1038/s41589-025-01908-1Alcanivorax borkumensis is a...
Chemical Decoding of Spatial Biology
1 day ago
Nature Chemical Biology, Published online: 08 May 2025; doi:10.1038/s41589-025-01910-7The spatial organization of...
Chemically programmable condensates for gene regulation
3 days ago
Nature Chemical Biology, Published online: 06 May 2025; doi:10.1038/s41589-025-01912-5We developed a ligand-responsive...
Fishing for covalent peptides
8 days ago
Nature Chemical Biology, Published online: 01 May 2025; doi:10.1038/s41589-025-01903-6Electrophilic phage display has...
A heme-dependent enzyme forms the hydrazine in the antibiotic negamycin
8 days ago
Nature Chemical Biology, Published online: 01 May 2025; doi:10.1038/s41589-025-01898-0Negamycin is a decades-old...
Facile generation of drug-like conformational antibodies specific for amyloid fibrils
10 days ago
Nature Chemical Biology, Published online: 29 April 2025; doi:10.1038/s41589-025-01881-9A quantitative fluorescence-activated cell...
Monitoring in real time and far-red imaging of H2O2 dynamics with subcellular resolution
11 days ago
Nature Chemical Biology, Published online: 28 April 2025; doi:10.1038/s41589-025-01891-7This paper highlights the...
Domain coupling in activation of a family C GPCR
15 days ago
Nature Chemical Biology, Published online: 25 April 2025; doi:10.1038/s41589-025-01895-3Combined single-molecule spectroscopy, hydrogen–deuterium...
Interfering with GPX4 degradation
15 days ago
Nature Chemical Biology, Published online: 25 April 2025; doi:10.1038/s41589-025-01873-9Inducing tumoral ferroptosis is...
PSAT1 impairs ferroptosis and reduces immunotherapy efficacy via GPX4 hydroxylation
15 days ago
Nature Chemical Biology, Published online: 25 April 2025; doi:10.1038/s41589-025-01887-3Interferon-γ (IFNγ)-activated calcium/calmodulin-dependent protein...
Advances in uncovering the mechanisms of macromolecular conformational entropy
15 days ago
Nature Chemical Biology, Published online: 24 April 2025; doi:10.1038/s41589-025-01879-3Protein conformational entropy plays...