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Last updated 5 days ago

MED1 IDR deacetylation controls stress responsive genes through RNA Pol II recruitment

5 days ago

Nature Chemical Biology, Published online: 23 October 2025; doi:10.1038/s41589-025-02035-7SIRT1-driven deacetylation of the...

Pausing for stress

5 days ago

Nature Chemical Biology, Published online: 23 October 2025; doi:10.1038/s41589-025-02006-yNew work reveals how...

DEFUSE-ing death

5 days ago

Nature Chemical Biology, Published online: 23 October 2025; doi:10.1038/s41589-025-02069-xDEFUSE-ing death

PATCHing the immune synapse

5 days ago

Nature Chemical Biology, Published online: 23 October 2025; doi:10.1038/s41589-025-02068-yPATCHing the immune synapse

Predicting proteome partners

5 days ago

Nature Chemical Biology, Published online: 23 October 2025; doi:10.1038/s41589-025-02067-zPredicting proteome partners

Site-resolved energetic information from HX–MS experiments

10 days ago

Nature Chemical Biology, Published online: 17 October 2025; doi:10.1038/s41589-025-02049-1Hydrogen exchange–mass spectrometry (HX–MS)...

Advances in integrating microbial metabolism with catalytic systems

11 days ago

Nature Chemical Biology, Published online: 16 October 2025; doi:10.1038/s41589-025-02048-2This Review discusses recent...

A small molecule targets LIC1 to suppress lung tumor growth by inducing autophagy

11 days ago

Nature Chemical Biology, Published online: 16 October 2025; doi:10.1038/s41589-025-02040-wPhenotypic screening of an...

Lighting up hydrogen peroxide

11 days ago

Nature Chemical Biology, Published online: 16 October 2025; doi:10.1038/s41589-025-02022-yHydrogen peroxide (H2O2) is...

Pseudouridines in translation

11 days ago

Nature Chemical Biology, Published online: 16 October 2025; doi:10.1038/s41589-025-02046-4A matching pseudouridine in...

A color-tailored fluorogenic sensor for hydrogen peroxide

11 days ago

Nature Chemical Biology, Published online: 16 October 2025; doi:10.1038/s41589-025-02036-6Hydrogen peroxide is a...

Deep learning-enabled design of macrocyclic peptide binders

13 days ago

Nature Chemical Biology, Published online: 15 October 2025; doi:10.1038/s41589-025-02062-4The discovery of macrocyclic...