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ClinicalTrials.gov: Roche | Last update posted in the last 14 days
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Last updated about 10 hours ago
Obinutuzumab for Systemic Lupus Erythematosus Pure Membranous Nephropathy: a Phase II Trial
1 day ago
Conditions: Lupus Nephritis; Membranous Nephropathy Interventions: Drug: Obinutuzumab Sponsors: Assistance Publique -...
A Study of Atezolizumab With or Without Tiragolumab in Participants With Unresectable Esophageal Squamous Cell Carcinoma Whose Cancers Have Not Progressed Following Definitive Concurrent Chemoradiotherapy
1 day ago
Conditions: Esophageal Squamous Cell Carcinoma Interventions: Drug: Tiragolumab; Drug: Atezolizumab; Drug: Tiragolumab...
A Study to Evaluate Ocrelizumab Treatment in Participants With Progressive Multiple Sclerosis
1 day ago
Conditions: Progressive Multiple Sclerosis (PMS) Interventions: Drug: Ocrelizumab Sponsors: Hoffmann-La Roche Active...
A Study to Determine the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of RO7806881 in Healthy Participants
1 day ago
Conditions: Healthy Volunteers Interventions: Drug: RO7806881; Drug: Placebo Sponsors: Hoffmann-La Roche Recruiting
AACR Adaptive Biomarker-Driven Organ Preservation Trial in Gastroesophageal Adenocarcinomas
1 day ago
Conditions: Gastroesophageal Adenocarcinoma Interventions: Drug: Tislelizumab; Drug: Leucovorin; Drug: Oxaliplatin; Drug: Fluorouracil...
A Study to Evaluate ALN-AGT01 RVR in Adult Patients With Mild to Moderate Hypertension Pretreated With Zilebesiran
1 day ago
Conditions: Hypertension Interventions: Drug: ALN-AGT01 RVR; Drug: Placebo; Drug: Zilebesiran Sponsors: Alnylam...
An Early-Stage Study in Multiple Clinics of How Afimkibart May Affect the Body's Processing of Medicines That Rely on Cytochrome P450 Enzymes in Participants With Ulcerative Colitis
1 day ago
Conditions: Active Ulcerative Colitis Interventions: Drug: Afimkibart; Drug: Caffeine; Drug: Warfarin; Drug...
A Study to Evaluate Overall Health, Physical Activity, and Joint Outcomes in Participants With Severe or Moderate Hemophilia A Without Factor VIII Inhibitors on Emicizumab Prophylaxis
1 day ago
Conditions: Severe Hemophilia A; Moderate Hemophilia A Interventions: Drug: Emicizumab Sponsors: Hoffmann-La...
Early Detection of Triple Negative Breast Cancer Relapse (CUPCAKE)
1 day ago
Conditions: Triple Negative Breast Cancer Interventions: Diagnostic Test: ctDNA monitoring; Diagnostic Test...
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
2 days ago
Conditions: Moderately to Severely Active Crohns Disease Interventions: Drug: Afimkibart; Drug: Placebo...
A Study of 36-Week Refill Exchanges of Port Delivery System (PDS) With Ranibizumab in nAMD
2 days ago
Conditions: Neovascular Age-related Macular Degeneration Interventions: Device: Susvimo PDS Implant; Drug: Ranibizumab...
AACR Adaptive Biomarker-Driven Organ Preservation Trial in Gastroesophageal Adenocarcinomas
2 days ago
Conditions: Gastroesophageal Adenocarcinoma Interventions: Drug: Tislelizumab; Drug: Leucovorin; Drug: Oxaliplatin; Drug: Fluorouracil...