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Last updated about 18 hours ago

Deep Learning-Driven Anticancer Drug Discovery: Emodepside as a Potential Therapeutic Candidate for Triple-Negative Breast Cancer

2 days ago

J Chem Inf Model. 2026 Jul 22. doi: 10.1021/acs.jcim.6c01061. Online ahead of...

The Nicotinamide Salvage Pathway is a Metabolic Vulnerability of High-Risk MDS Stem Cells

3 days ago

Blood Cancer Discov. 2026 Jul 21. doi: 10.1158/2643-3230.BCD-25-0498. Online ahead of print.ABSTRACTHigh-risk...

Structural basis for a p21-activated kinase 4 and nicotinamide phosphoribosyltransferase dual inhibitor

4 days ago

Acta Crystallogr D Struct Biol. 2026 Aug 1. doi: 10.1107/S2059798326006145. Online ahead...

MAP2K6 reprograms NAD(+) metabolism via the HMGA1-NAMPT axis to sensitize ovarian cancer cells to PARP inhibition

7 days ago

Cell Death Dis. 2026 Jul 17. doi: 10.1038/s41419-026-09104-2. Online ahead of print.ABSTRACTPARP...

Targeting the NAD+ salvage pathway blocks metabolic recovery and enhances β-lapachone toxicity in NQO1-expressing glioblastoma cells

8 days ago

Cancer Res Commun. 2026 Jul 16. doi: 10.1158/2767-9764.CRC-26-0275. Online ahead of print.ABSTRACTGlioblastoma...

Adipocytokine Profiles in Type 2 Diabetes Mellitus and Autoimmune Thyroid Disease: Associations With Metabolic and Hormonal Parameters

9 days ago

Physiol Res. 2026 Jul 15;75(3):443-456.ABSTRACTType 2 diabetes mellitus (T2DM) and autoimmune thyroid...

Targeting Sirtuins in Thyroid Cancer: Mechanisms, Drug Development, and Emerging Roles in Tumor Immunity and Ferroptosis

9 days ago

Cancers (Basel). 2026 Jun 27;18(13):2093. doi: 10.3390/cancers18132093.ABSTRACTThyroid cancer (TC) is the most...

A novel NAMPT activator ameliorates obesity by repressing ACSL1-dependent lipid synthesis

9 days ago

Acta Pharm Sin B. 2026 Jul;16(7):4478-4490. doi: 10.1016/j.apsb.2026.03.039. Epub 2026 Mar 25.ABSTRACTExcessive...

Perithyroidal Adipose Tissue Drives Thyroid Tumorigenesis through Adipokine Signaling and Immune Suppression

9 days ago

Research (Wash D C). 2026 Jul 14;9:1360. doi: 10.34133/research.1360. eCollection 2026.ABSTRACTThe perithyroidal...

Integrative multi-omics analysis identifies histone methyltransferase SUV420H2 as a prognostic biomarker in clear cell renal cell carcinoma

10 days ago

Discov Oncol. 2026 Jul 14. doi: 10.1007/s12672-026-05556-2. Online ahead of print.ABSTRACTRenal cell...

Ergothioneine attenuates age-related declines in circadian rhythmicity

11 days ago

Biochem Biophys Res Commun. 2026 Jul 11;830:154272. doi: 10.1016/j.bbrc.2026.154272. Online ahead of...