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Last updated 3 months ago

Chemotherapy-driven intestinal dysbiosis and indole-3-propionic acid rewire myelopoiesis to promote a metastasis-refractory state

7 months ago

Nat Commun. 2025 Dec 15;17(1):832. doi: 10.1038/s41467-025-67169-7.ABSTRACTThe contribution of chemotherapy-induced tissue injury...

Transient hepatic reconstitution of trophic factors enhances aged immunity

7 months ago

Nature. 2026 Feb;650(8101):481-489. doi: 10.1038/s41586-025-09873-4. Epub 2025 Dec 17.ABSTRACTAgeing erodes human immunity...

Harnessing multivalency and FcγRIIB engagement to augment anti-CD27 immunotherapy

7 months ago

Nat Commun. 2025 Dec 20;17(1):1122. doi: 10.1038/s41467-025-67882-3.ABSTRACTDespite significant clinical progress, checkpoint blockade...

IL-33 expands plasma cells, disrupts germinal centers, and increases autoantibody production in mice

7 months ago

Nat Commun. 2025 Dec 23;17(1):1102. doi: 10.1038/s41467-025-67867-2.ABSTRACTIL-33 is an inflammatory cytokine contributing...

GBP2 condensates promote ferroptosis to sensitize anti-PD-L1 immunotherapy in melanoma

7 months ago

Nat Commun. 2025 Dec 24;17(1):964. doi: 10.1038/s41467-025-67690-9.ABSTRACTThe mechanisms underlying the limited response...

IL-17a induces age-related olfactory dysfunction by impairing regeneration and promoting respiratory metaplasia in mice

7 months ago

Nat Commun. 2025 Dec 29;17(1):1036. doi: 10.1038/s41467-025-67786-2.ABSTRACTThe olfactory epithelium (OE) undergoes life-long...

A Plug-in system for reprogramming the editing patterns of base editors

7 months ago

Nat Commun. 2025 Dec 20;17(1):910. doi: 10.1038/s41467-025-67632-5.ABSTRACTDNA base editors are transformative genome...

Tumor-produced ammonia is metabolized by regulatory T cells to further impede anti-tumor immunity

7 months ago

Cell. 2026 Jan 22;189(2):418-434.e24. doi: 10.1016/j.cell.2025.11.034. Epub 2025 Dec 24.ABSTRACTMechanisms of adaptation...

γδ T cell receptor recognition of CD1d in a lipid-independent manner

7 months ago

Nat Commun. 2025 Dec 29;17(1):926. doi: 10.1038/s41467-025-67653-0.ABSTRACTThe monomorphic antigen-presenting molecule CD1d presents...

Primary SARS-CoV-2 exposure by vaccination or infection shapes immune responses to omicron variants among a Spanish cohort

7 months ago

Nat Commun. 2025 Dec 13;17(1):863. doi: 10.1038/s41467-025-67577-9.ABSTRACTThe comparison between vaccine-induced and infection-acquired...

Aiolos restricts the generation of antigen-inexperienced, virtual memory CD8(+) T cells in mice

7 months ago

Nat Commun. 2025 Dec 14;17(1):839. doi: 10.1038/s41467-025-67540-8.ABSTRACTCD8+ virtual memory T (TVM) cells...

Dysfunctional CD4 T cells in an oncovirus-specific TCR-transgenic in vivo model

7 months ago

Nat Commun. 2025 Dec 18;17(1):870. doi: 10.1038/s41467-025-67588-6.ABSTRACTT cell exhaustion has been implicated...