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Most Recent Articles: BMC Bioinformatics

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Last updated about 21 hours ago

Coconut: covariate-assisted composite null hypothesis testing with applications to replicability analysis of high-throughput experimental data

about 21 hours ago

Multiple testing of composite null hypotheses is critical for identifying simultaneous signals...

Automated sparse feature selection in high-dimensional proteomics data via 1-bit compressed sensing and K-Medoids clustering

about 21 hours ago

High-dimensional proteomics data present significant challenges in biomarker discovery due to technical...

Replacing normalizations with interval assumptions enhances differential expression and differential abundance analyses

about 21 hours ago

Methods for differential expression and differential abundance analysis often rely on normalization...

Adaptive gradient scaling: integrating Adam and landscape modification for protein structure prediction

about 21 hours ago

Protein structure prediction is one of the most important scientific problems, on...

2dSpAn-Auto: an automated tool for analysis of two-dimensional dendritic spine images

about 21 hours ago

Quantitative analysis of dendritic spine morphology and density is crucial for understanding...

Differential expression analysis with inmoose, the integrated multi-omic open-source environment in Python

10 days ago

Differential gene expression analysis is a prominent technique for the analysis of...

PRCFX-DT: a new graph-based approach for feature selection and classification of genomic sequences

16 days ago

In recent years, viral diseases have exhibited a significant incidence of infections...

Start & Stop: a PhysiCell and PhysiBoSS 2.0 add-on for interactive simulation control

22 days ago

In computational biology, in silico simulators are vital for exploring and understanding...

SCATrans: semantic cross-attention transformer for drug–drug interaction predication through multimodal biomedical data

23 days ago

Predicting potential drug-drug interactions (DDIs) from biomedical data plays a critical role...

SEQSIM: A novel bioinformatics tool for comparisons of promoter regions—a case study of calcium binding protein spermatid associated 1 (CABS1)

24 days ago

Understanding transcriptional regulation requires an in-depth analysis of promoter regions, which house...

Bigpicc: a graph-based approach to identifying carcinogenic gene combinations from mutation data

26 days ago

Genome data from cancer patients represents relationships between the presence of a...

‘gitana’ (phyloGenetic Imaging Tool for Adjusting Nodes and other Arrangements), a tool for plotting phylogenetic trees into ready-to-publish figures

28 days ago

Phylogenetic trees are essential diagrams used in different sciences, such as evolutionary...