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Journal of Medicinal Chemistry: Latest Articles (ACS Publications)
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Last updated almost 2 years ago
[ASAP] A Molecular Toolbox of Positron Emission Tomography Tracers for General Anesthesia Mechanism Research
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.2c01965
[ASAP] X‑ray Crystal Structure-Guided Discovery of Novel Indole Analogues as Colchicine-Binding Site Tubulin Inhibitors with Immune-Potentiating and Antitumor Effects against Melanoma
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00011
[ASAP] Rationally Engineered CYP3A4 Fluorogenic Substrates for Functional Imaging Analysis and Drug–Drug Interaction Studies
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00101
[ASAP] Discovery of Potent and Wild-Type-Sparing Fourth-Generation EGFR Inhibitors for Treatment of Osimertinib-Resistance NSCLC
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00277
[ASAP] Prodrug Strategies for the Development of β‑l‑5-((E)‑2-Bromovinyl)-1-((2S,4S)‑2-(hydroxymethyl)-1,3-(dioxolane-4-yl))uracil (l‑BHDU) against Varicella Zoster Virus (VZV)
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00545
[ASAP] Small Molecules Targeting DNA Polymerase Theta (POLθ) as Promising Synthetic Lethal Agents for Precision Cancer Therapy
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.2c02101
[ASAP] Design, Synthesis, and Evaluation of (R)‑8-((Tetrahydrofuran-2-yl)methyl)pyrido[2,3‑d]pyrimidin-7-ones as Novel Selective ACK1 Inhibitors to Combat Acquired Resistance to the Third-Generation EGFR Inhibitor
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00319
[ASAP] Ψ and χ Angle Constrains at the C‑Terminus Trp Position of the Melanotropin Tetrapeptide Ac-His‑d‑Phe-Arg-Trp-NH2 Lead to Potent and Selective Agonists at hMC1R and hMC4R
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.2c01794
[ASAP] Virtual Special Issue: New Drug Modalities in Medicinal Chemistry, Pharmacology, and Translational Science
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00701
[ASAP] Design, Synthesis, Biological Evaluation, and Crystallographic Study of Novel Purine Nucleoside Phosphorylase Inhibitors
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.2c02097
[ASAP] Transformation of a Dopamine D2 Receptor Agonist to Partial Agonists as Novel Antipsychotic Agents
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00098
[ASAP] Design, Synthesis, and Bioevaluation of Novel MyD88 Inhibitor c17 against Acute Lung Injury Derived from the Virtual Screen
about 2 years ago
Journal of Medicinal ChemistryDOI: 10.1021/acs.jmedchem.3c00359