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clinicaltrials.gov

ClinicalTrials.gov: Glioma OR Astrocytoma OR Oligodendroglioma | Other terms: IDH Mutation | Interventional, Expanded Access studies | Last update posted in the last 14 days

Get the latest updates from ClinicalTrials.gov: Glioma OR Astrocytoma OR Oligodendroglioma | Other terms: IDH Mutation | Interventional, Expanded Access studies | Last update posted in the last 14 days directly as they happen.

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Last updated 5 days ago

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

6 days ago

Conditions: Recurrent Glioblastoma, IDH-Wildtype; Recurrent Gliosarcoma; Recurrent WHO Grade 4 Glioma Interventions...

Telaglenastat With Radiation Therapy and Temozolomide in Treating Patients With IDH-Mutated Diffuse Astrocytoma or Anaplastic Astrocytoma

6 days ago

Conditions: Astrocytoma, IDH-Mutant, Grade 2; Astrocytoma, IDH-Mutant, Grade 3 Interventions: Other: Questionnaire...

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

12 days ago

Conditions: Anaplastic Astrocytoma; Anaplastic Oligoastrocytoma; Anaplastic Oligodendroglioma; Diffuse Astrocytoma; Glioma; Oligoastrocytoma; Oligodendroglioma...

Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma

12 days ago

Conditions: Anaplastic Astrocytoma; Glioblastoma; Oligodendroglioma; Supratentorial Glioblastoma Interventions: Drug: Extended Release Flucytosine...

Window of Opportunity Study of DSP-0390 in Gliomas

13 days ago

Conditions: Glioma, Malignant; IDH Mutation Interventions: Drug: DSP-0390 Sponsors: Washington University School...

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

15 days ago

Conditions: Recurrent Ependymoma; Recurrent Ewing Sarcoma; Recurrent Hepatoblastoma; Recurrent Langerhans Cell Histiocytosis...

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

15 days ago

Conditions: Astrocytoma, IDH-Mutant, Grade 4; Diffuse Glioma; Glioblastoma, IDH-Wildtype; Secondary Glioblastoma Interventions...

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

18 days ago

Conditions: Brain Tumor; Cancer Interventions: Drug: Zotiraciclib Sponsors: National Cancer Institute (NCI)...

PRO-GLIO: PROton Versus Photon Therapy in IDH-mutated Diffuse Grade II and III GLIOmas

18 days ago

Conditions: Oligodendroglioma; Oligodendroglioma, Anaplastic; Diffuse Astrocytoma, IDH-Mutant Interventions: Radiation: Radiation therapy Sponsors...

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

20 days ago

Conditions: Brain Tumor; Cancer Interventions: Drug: Zotiraciclib Sponsors: National Cancer Institute (NCI)...

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

21 days ago

Conditions: Recurrent Ependymoma; Recurrent Ewing Sarcoma; Recurrent Hepatoblastoma; Recurrent Langerhans Cell Histiocytosis...

Window of Opportunity Study of DSP-0390 in Gliomas

28 days ago

Conditions: Glioma, Malignant; IDH Mutation Interventions: Drug: DSP-0390 Sponsors: Washington University School...