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clinicaltrials.gov

ClinicalTrials.gov: Glioma OR Astrocytoma OR Oligodendroglioma | Other terms: IDH Mutation | Interventional, Expanded Access studies | Last update posted in the last 14 days

Get the latest updates from ClinicalTrials.gov: Glioma OR Astrocytoma OR Oligodendroglioma | Other terms: IDH Mutation | Interventional, Expanded Access studies | Last update posted in the last 14 days directly as they happen.

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Latest posts

Last updated 1 day ago

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

3 days ago

Conditions: Glioma; Gliomas; High Grade Glioma; Malignant Glioma; Low Grade Glioma Interventions...

All-Trans Retinoic Acid (ATRA) Plus PD-1 Inhibition in Recurrent IDH-Mutant Glioma

5 days ago

Conditions: Glioma; IDH Mutation; Astrocytoma; Oligodendroglioma Interventions: Drug: Retifanlimab; Drug: All-trans retinoic...

Clinical Study for the Safety and Therapeutic Efficacy of the AI-QMMM Designed TamavaqTM Personalised Vaccine in Patients With Newly Diagnosed Glioma.

8 days ago

Conditions: Glioma Interventions: Biological: Biological: personalized vaccine Based on genetic and transcriptional...

Study of How Safe and Effective Tarlatamab is in Brain Cancers

8 days ago

Conditions: Astrocytic Tumor; Oligodendroglial Tumor Interventions: Drug: Tarlatamab Sponsors: University Health Network...

A Study of HMPL-306 in Advanced Solid Tumors With IDH Mutations

11 days ago

Conditions: Isocitrate Dehydrogenase Gene Mutation Interventions: Drug: HMPL-306 Sponsors: Hutchmed Terminated

Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma

16 days ago

Conditions: IDH1-mutant Glioma; IDH2-mutant Glioma Interventions: Drug: Vorasidenib; Drug: Temozolomide (TMZ) Sponsors...

Pembrolizumab, Olaparib, and Temozolomide for People With Glioma

16 days ago

Conditions: Glioma Interventions: Drug: Pembrolizumab; Combination Product: Olaparib and Temozolomide Sponsors: Memorial...

Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies

16 days ago

Conditions: Glioma; Glioblastoma; Metastatic Malignant Neoplasm in the Brain Interventions: Procedure: Microdialysis...

Niraparib In Recurrent IDH 1/2 Gliomas

18 days ago

Conditions: Low-grade Glioma; IDH2 Gene Mutation; Recurrent Glioma; IDH1 Mutation; Glioma, Malignant...

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

18 days ago

Conditions: Astrocytoma, IDH-Mutant, Grade 4; Diffuse Glioma; Glioblastoma, IDH-Wildtype; Secondary Glioblastoma Interventions...

A Study of IDH305 in Patients With Advanced Malignancies That Harbor IDH1R132 Mutations

29 days ago

Conditions: Advanced Malignancies That Harbor IDHR132 Mutations Interventions: Drug: IDH305 Sponsors: Novartis...

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

about 1 month ago

Conditions: Brain Tumor; Cancer Interventions: Drug: Zotiraciclib Sponsors: National Cancer Institute (NCI)...