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clinicaltrials.gov

ClinicalTrials.gov: Glioma OR Astrocytoma OR Oligodendroglioma | Other terms: IDH Mutation | Interventional, Expanded Access studies | Last update posted in the last 14 days

Get the latest updates from ClinicalTrials.gov: Glioma OR Astrocytoma OR Oligodendroglioma | Other terms: IDH Mutation | Interventional, Expanded Access studies | Last update posted in the last 14 days directly as they happen.

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Last updated about 10 hours ago

VorAsidenib With Lomustine In Patients With rEcurrent IDH-mutaNT Glioma Harboring IDH1 and/or IDH2 Mutations

4 days ago

Conditions: Brain Cancer Interventions: Drug: Vorasidenib; Drug: Lomustine Sponsors: Megan Mantica; Institut...

Vorasidenib in Combination With Temozolomide (TMZ) in IDH-mutant Glioma

5 days ago

Conditions: IDH1-mutant Glioma; IDH2-mutant Glioma Interventions: Drug: Vorasidenib; Drug: Temozolomide (TMZ) Sponsors...

Phase 3 Study of Vorasidenib (S095032/AG-881) in Asian Participants With Residual or Recurrent Grade 2 Glioma With an IDH1 orIDH2 Mutation

5 days ago

Conditions: Residual or Recurrent Grade 2 IDH Mutant Glioma Interventions: Drug: Vorasidenib...

A Phase I/II Study of Zotiraciclib for Recurrent Malignant Gliomas With Isocitrate Dehydrogenase 1 or 2 (IDH1 or IDH2) Mutations

6 days ago

Conditions: Brain Tumor; Cancer Interventions: Drug: Zotiraciclib Sponsors: National Cancer Institute (NCI)...

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

11 days ago

Conditions: Glioma; Gliomas; High Grade Glioma; Malignant Glioma; Low Grade Glioma Interventions...

A Study Testing the Effect of Immunotherapy (Ipilimumab and Nivolumab) in Patients With Recurrent Glioma With Elevated Mutational Burden

11 days ago

Conditions: Astrocytoma, IDH-Mutant, Grade 4; Diffuse Glioma; Glioblastoma, IDH-Wildtype; Secondary Glioblastoma Interventions...

Ivosidenib in Treating Patients With Advanced Solid Tumors, Lymphoma, or Histiocytic Disorders With IDH1 Mutations (A Pediatric MATCH Treatment Trial)

11 days ago

Conditions: Recurrent Ependymoma; Recurrent Ewing Sarcoma; Recurrent Hepatoblastoma; Recurrent Langerhans Cell Histiocytosis...

Hyperpolarized Carbon-13 Alpha-ketoglutarate Imaging in IDH Mutant Glioma

13 days ago

Conditions: Adult Gliomas, Mixed Interventions: Drug: Hyperpolarized Carbon 13 Alpha-ketoglutarate (HP C13-aKG)...

Proton Beam or Intensity-Modulated Radiation Therapy in Preserving Brain Function in Patients With IDH Mutant Grade II or III Glioma

14 days ago

Conditions: Anaplastic Astrocytoma; Anaplastic Oligoastrocytoma; Anaplastic Oligodendroglioma; Diffuse Astrocytoma; Glioma; Oligoastrocytoma; Oligodendroglioma...

Studying the Biology of IDH-mutant Gliomas Via Longitudinal Observation of 2-hydroxyglutarate (2-HG) Using MR Spectroscopy

18 days ago

Conditions: Glioma; Gliomas; High Grade Glioma; Malignant Glioma; Low Grade Glioma Interventions...

Observational Study of Responses to Treatments in Advanced Central Nervous System (CNS) Tumors

18 days ago

Conditions: Recurrent CNS Tumors; Brain Cancer; Gliomas; IDH-wildtype Gliomas; IDH-mutant Gliomas; Rare...

Testing the Combination of Anti-cancer Drugs Actimab-A and Cemiplimab (REGN2810) to Improve Outcomes for Patients With Recurrent Glioblastoma

27 days ago

Conditions: Recurrent Glioblastoma, IDH-Wildtype; Recurrent Gliosarcoma; Recurrent WHO Grade 4 Glioma Interventions...