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Last updated 4 days ago

A pandemic agreement is within reach | Science

4 days ago

At the end of May, 194 member states of the World Health...

Repair of CRISPR-guided RNA breaks enables site-specific RNA excision in human cells | Science

9 days ago

Genome editing with CRISPR RNA-guided endonucleases generates DNA breaks that are resolved...

Cleavage-independent activation of ancient eukaryotic gasdermins and structural mechanisms | Science

9 days ago

Gasdermins (GSDMs) are pore-forming proteins that execute pyroptosis for immune defense. GSDMs...

Isotopic evidence of long-lived volcanism on Io | Science

16 days ago

Jupiter’s moon Io hosts extensive volcanism, driven by tidal heating. The isotopic...

Dating the Solar System’s giant planet orbital instability using enstatite meteorites | Science

18 days ago

The giant planets of the Solar System formed on initially compact orbits...

Human telomere length is chromosome end–specific and conserved across individuals | Science

23 days ago

Short telomeres cause age-related disease and long telomeres predispose to cancer; however...

Sexual dimorphism in skin immunity is mediated by an androgen-ILC2-dendritic cell axis | Science

about 1 month ago

Males and females exhibit profound differences in immune responses and disease susceptibility...

Sex differences in tissue immunity | Science

about 1 month ago

Androgen signaling skews skin immunity toward reduced inflammation in male mice

Antibacterial activity of nonantibiotics is orthogonal to standard antibiotics | Science

about 1 month ago

Numerous nonantibiotic drugs have potent antibacterial activity and can adversely impact the...

Sister chromatid cohesion establishment during DNA replication termination | Science

about 1 month ago

Newly copied sister chromatids are tethered together by the cohesin complex, but...

Sister chromatid cohesion establishment during DNA replication termination | Science

about 2 months ago

Newly copied sister chromatids are tethered together by the cohesin complex, but...

Misconduct’s forgotten victims | Science

about 2 months ago

The drumbeat of complaints over the poor treatment of graduate students and...