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Last updated 2 days ago

Affinity maturation of antibody responses is mediated by differential plasma cell proliferation | Science

2 days ago

Increased antibody affinity over time after vaccination, known as affinity maturation, is...

Identification of antigen-presenting cell–T cell interactions driving immune responses to food | Science

2 days ago

The intestinal immune system must concomitantly tolerate food and commensals and protect...

Structural basis of H3K36 trimethylation by SETD2 during chromatin transcription | Science

9 days ago

During transcription, RNA polymerase II traverses through chromatin, and post-translational modifications including...

Confronting risks of mirror life | Science

9 days ago

Broad discussion is needed to chart a path forward.

Antiviral signaling of a type III CRISPR-associated deaminase | Science

9 days ago

Prokaryotes have evolved diverse defense strategies against viral infection, such as foreign...

Nutrient-driven histone code determines exhausted CD8+ T cell fates | Science

9 days ago

ACLY-deficient CAR T cells targeting the tumor-associated antigen disialoganglioside GD2 (GD2 CAR...

Recent global temperature surge intensified by record-low planetary albedo | Science

16 days ago

In 2023, the global mean temperature soared to almost 1.5K above the...

Molecular basis of FIGNL1 in dissociating RAD51 from DNA and chromatin | Science

16 days ago

Maintaining genome integrity is an essential and challenging process. RAD51 recombinase, the...

A panoramic view of cell population dynamics in mammalian aging | Science

23 days ago

To elucidate aging-associated cellular population dynamics, we present PanSci, a single-cell transcriptome...

Natural selection could determine whether Acropora corals persist under expected climate change | Science

23 days ago

Marine heatwaves are intensifying under climate change, exposing populations of reef-building corals...

Rapid in silico directed evolution by a protein language model with EVOLVEpro | Science

about 1 month ago

Directed protein evolution is central to biomedical applications but faces challenges like...

Loss of Earth’s old, wise, and large animals | Science

about 1 month ago

Earth’s old animals are in decline. Despite this, emerging research is revealing...