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Last updated 3 days ago

Multistate and functional protein design using RoseTTAFold sequence space diffusion

3 days ago

Nature Biotechnology, Published online: 25 September 2024; doi:10.1038/s41587-024-02395-wProteinGenerator simultaneously generates protein sequences...

Increasing intracellular dNTP levels improves prime editing efficiency

3 days ago

Nature Biotechnology, Published online: 25 September 2024; doi:10.1038/s41587-024-02405-xPrime editing efficiency is enhanced...

Chemical and topological design of multicapped mRNA and capped circular RNA to augment translation

5 days ago

Nature Biotechnology, Published online: 23 September 2024; doi:10.1038/s41587-024-02393-ymRNA cap designs boost translation...

Coordinated, multicellular patterns of transcriptional variation that stratify patient cohorts are revealed by tensor decomposition

5 days ago

Nature Biotechnology, Published online: 23 September 2024; doi:10.1038/s41587-024-02411-zUnsupervised analysis of single-cell RNA-sequencing...

Scalable and unsupervised discovery from raw sequencing reads using SPLASH2

5 days ago

Nature Biotechnology, Published online: 23 September 2024; doi:10.1038/s41587-024-02381-2SPLASH2 speeds up analysis of...

Plastic-eating bacteria boost growing business of bioremediation

5 days ago

Nature Biotechnology, Published online: 23 September 2024; doi:10.1038/s41587-024-02401-1Bacteria, fungi and plants can...

Building better mRNA for therapeutics

5 days ago

Nature Biotechnology, Published online: 23 September 2024; doi:10.1038/s41587-024-02424-8Redesigning mRNA with chemo-topological strategies...

Targeting double-stranded nucleic acids using the λExo–pDNA system

10 days ago

Nature Biotechnology, Published online: 18 September 2024; doi:10.1038/s41587-024-02409-7λ exonuclease (λExo) binds 5′-phosphorylated...

A developmental route to hematopoietic stem cells

10 days ago

Nature Biotechnology, Published online: 18 September 2024; doi:10.1038/s41587-024-02398-7A differentiation method informed by...

Bacteriophage λ exonuclease and a 5′-phosphorylated DNA guide allow PAM-independent targeting of double-stranded nucleic acids

10 days ago

Nature Biotechnology, Published online: 18 September 2024; doi:10.1038/s41587-024-02388-9A λ exonuclease system exhibits...

An experimental census of retrons for DNA production and genome editing

11 days ago

Nature Biotechnology, Published online: 17 September 2024; doi:10.1038/s41587-024-02384-zGenome editing tools are developed...

Bioremediation

14 days ago

Nature Biotechnology, Published online: 13 September 2024; doi:10.1038/s41587-024-02374-1Recent patents relating to compositions...