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Last updated about 11 hours ago

Severus detects somatic structural variation and complex rearrangements in cancer genomes using long-read sequencing

about 11 hours ago

Nature Biotechnology, Published online: 04 April 2025; doi:10.1038/s41587-025-02618-8Complex structural variations and rearrangements...

Scalable spatial transcriptomics through computational array reconstruction

1 day ago

Nature Biotechnology, Published online: 03 April 2025; doi:10.1038/s41587-025-02612-0An imaging-free spatial transcriptomics method...

Improved RNA base editing with guide RNAs mimicking highly edited endogenous ADAR substrates

1 day ago

Nature Biotechnology, Published online: 03 April 2025; doi:10.1038/s41587-025-02628-6Adenosine deaminase acting on RNA-based...

Openness guides discovery

2 days ago

Nature Biotechnology, Published online: 02 April 2025; doi:10.1038/s41587-025-02635-7Openness guides discovery

The emerging landscape of engineered bacteria cancer therapies

3 days ago

Nature Biotechnology, Published online: 01 April 2025; doi:10.1038/s41587-025-02623-xOur ability to use engineered...

Engineering a photoactivatable A-to-I RNA base editor for gene therapy in vivo

4 days ago

Nature Biotechnology, Published online: 31 March 2025; doi:10.1038/s41587-025-02610-2A light-inducible RNA base editor...

Circular RNA aptamers targeting neuroinflammation ameliorate Alzheimer disease phenotypes in mouse models

4 days ago

Nature Biotechnology, Published online: 31 March 2025; doi:10.1038/s41587-025-02624-wCircular RNA aptamers dampen Alzheimer...

A light-inducible RNA base editor for precise gene expression

4 days ago

Nature Biotechnology, Published online: 31 March 2025; doi:10.1038/s41587-025-02621-zA lack of broadly applicable...

Sensitive detection of gene transfer in a microbial community

7 days ago

Nature Biotechnology, Published online: 28 March 2025; doi:10.1038/s41587-025-02639-3Gene transfer enables bacteria to...

Volumetric imaging using a distributed molecular network

8 days ago

Nature Biotechnology, Published online: 27 March 2025; doi:10.1038/s41587-025-02640-wWe introduce volumetric DNA microscopy...

Spatial transcriptomic imaging of an intact organism using volumetric DNA microscopy

8 days ago

Nature Biotechnology, Published online: 27 March 2025; doi:10.1038/s41587-025-02613-zVolumetric DNA microscopy captures spatial...

Induced proximity at the cell surface

9 days ago

Nature Biotechnology, Published online: 26 March 2025; doi:10.1038/s41587-025-02592-1Technologies to modulate induced proximity...