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The human social cognitive network contains multiple regions within the amygdala | Science Advances

2 days ago

Abstract Reasoning about someone’s thoughts and intentions—i.e., forming a “theory of mind”—is...

Enhanced dual-mode imaging: Superior photoacoustic and ultrasound endoscopy in live pigs using a transparent ultrasound transducer | Science Advances

2 days ago

Abstract Dual-mode photoacoustic/ultrasound endoscopy (ePAUS) is a promising tool for preclinical and...

Multiplex digital profiling of DNA methylation heterogeneity for sensitive and cost-effective cancer detection in low-volume liquid biopsies | Science Advances

2 days ago

Abstract Molecular alterations in cancerous tissues exhibit intercellular genetic and epigenetic heterogeneity,...

Zircon trace element evidence for early hydrothermal activity on Mars | Science Advances

2 days ago

Abstract Finding direct evidence for hydrous fluids on early Mars is of...

Monoamine transporter ubiquitination and inward-open conformation synergistically maximize transporter endocytosis | Science Advances

2 days ago

Abstract Monoamine transporters function in neuronal membranes to control extracellular concentrations of...

CalDAG-GEFI acts as a guanine nucleotide exchange factor for LRRK2 to regulate LRRK2 function and neurodegeneration | Science Advances

2 days ago

Abstract Mutations in LRRK2 are the most common genetic cause of Parkinson’s...

Structural characterization and AlphaFold modeling of human T cell receptor recognition of NRAS cancer neoantigens | Science Advances

2 days ago

Abstract T cell receptors (TCRs) that recognize cancer neoantigens are important for...

Multifunctional hydrogel electronics for closed-loop antiepileptic treatment | Science Advances

2 days ago

Abstract Closed-loop strategies offer advanced therapeutic potential through intelligent disease management. Here,...

Four SpsP neurons are an integrating sleep regulation hub in Drosophila | Science Advances

2 days ago

Abstract Sleep is essential and highly conserved, yet its regulatory mechanisms remain...

Submillimeter fiber robots capable of decoupled macro-micro motion for endoluminal manipulation | Science Advances

2 days ago

Abstract Endoluminal and endocavitary intervention via natural orifices of the body is...

Catalytic kinetic resolution of helical polycyclic phenols via an organocatalyzed enantioselective dearomative amination reaction | Science Advances

2 days ago

Abstract Despite the considerable potential applications for helically chiral molecules across various...