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Last updated 3 days ago
FcγR binding differentially contributes to protection by two human monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein | Science Translational Medicine
3 days ago
Fc binding is dispensable for protection against malaria by CIS43LS and L9LS...
Glutathione-specific gamma–glutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis | Science Translational Medicine
3 days ago
CHAC1 is a kidney disease risk gene, and removal of one copy...
Activation and targetability of TYMP–IL-6–TF signaling in the skin microenvironment in uremic calciphylaxis | Science Translational Medicine
3 days ago
Microvascular thrombi in calciphylaxis skin can be pharmacologically targeted by anti–IL-6 therapies.
A microfluidic wearable device for wound exudate management and analysis in human chronic wounds | Science Translational Medicine
3 days ago
A smart bandage enables efficient wound fluid capture and multiplexed biosensing of...
A high-resolution screen identifies a preexisting beta-lactam that specifically treats Lyme disease in mice | Science Translational Medicine
3 days ago
Piperacillin, an FDA-approved beta-lactam, is effective at killing the Lyme disease–causing agent...
Erratum for the Research Article “Broadly neutralizing antibodies targeting pandemic GII.4 variants or seven GII genotypes of human norovirus” by J. Park et al. | Science Translational Medicine
3 days ago
In the Research Article “Broadly neutralizing antibodies targeting pandemic GII.4 variants or...
The peptidoglycan of Borrelia burgdorferi can persist in discrete tissues and cause systemic responses consistent with chronic illness | Science Translational Medicine
3 days ago
Polymeric Borrelia burgdorferi peptidoglycan cell wall can persist in murine livers for...
Vaccinology in the artificial intelligence era | Science Translational Medicine
10 days ago
Artificial intelligence has the potential to revolutionize the entire vaccinology pipeline, but...
Condensation of cellular prion protein promotes renal fibrosis through the TBK1-IRF3 signaling axis | Science Translational Medicine
10 days ago
PrPC activates TBK1-IRF3 signaling to worsen renal fibrosis in mice, highlighting amlexanox...
Liver-targeted allergen immunotherapy rapidly and safely induces antigen-specific tolerance to treat allergic airway disease in mice | Science Translational Medicine
10 days ago
Liver-targeted synthetically mannosylated allergens induce allergen-specific tolerance in preclinical models of allergic...
Expansion of a bacterial operon during cancer treatment ameliorates fluoropyrimidine toxicity | Science Translational Medicine
10 days ago
Gut bacterial enzymes can be used to predict and prevent anticancer drug...
Pentatricopeptide repeat protein targeting CUG repeat RNA ameliorates RNA toxicity in a myotonic dystrophy type 1 mouse model | Science Translational Medicine
10 days ago
AAV9-mediated systemic delivery of a protein that targets CUG repeat RNA ameliorates...