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Last updated about 3 hours ago
A thin cryobiopsy device compatible with transnasal endoscopy for the gastrointestinal tract | Science Translational Medicine
about 3 hours ago
An ultrasmall, image-guided cryobiopsy device supports transnasal biopsy of the gastrointestinal tract...
Hypoglycemia promotes inner blood-retinal barrier breakdown and retinal vascular leakage in diabetic mice | Science Translational Medicine
about 3 hours ago
Hypoglycemia promotes hypoxia-inducible factor-1 (HIF-1)– and HIF-2–dependent retinal vascular hyperpermeability in diabetic...
Objective autonomic signatures of tinnitus and sound sensitivity disorders | Science Translational Medicine
about 3 hours ago
Emotionally evocative sounds elicit pupil dilations and facial movements that index the...
Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders | Science Translational Medicine
about 3 hours ago
A tricyclic depletion protocol allows for microglia replacement without preconditioning and mitigates...
Somatic mosaicism in the buccal mucosa reflects lifestyle and germline risk factors for esophageal squamous cell carcinoma | Science Translational Medicine
about 3 hours ago
Noninvasive sampling of the buccal mucosa can detect somatic mosaicism that marks...
Inclusion of a retroviral protease enhances the immunogenicity of VLP-forming mRNA vaccines against HIV-1 or SARS-CoV-2 in mice | Science Translational Medicine
about 3 hours ago
Addition of a retroviral protease to cleave Gag and generate mature virus-like...
Hypoxia-inducible factors link poor glycemic control to diabetic retinopathy | Science Translational Medicine
about 3 hours ago
Hypoglycemic episodes exacerbate diabetic eye disease, which is targetable by dual-HIF inhibition...
FcγR binding differentially contributes to protection by two human monoclonal antibodies targeting Plasmodium falciparum circumsporozoite protein | Science Translational Medicine
7 days ago
Fc binding is dispensable for protection against malaria by CIS43LS and L9LS...
Glutathione-specific gamma–glutamylcyclotransferase 1 (CHAC1) increases kidney disease risk by modulating ferroptosis | Science Translational Medicine
7 days ago
CHAC1 is a kidney disease risk gene, and removal of one copy...
Activation and targetability of TYMP–IL-6–TF signaling in the skin microenvironment in uremic calciphylaxis | Science Translational Medicine
7 days ago
Microvascular thrombi in calciphylaxis skin can be pharmacologically targeted by anti–IL-6 therapies.
A microfluidic wearable device for wound exudate management and analysis in human chronic wounds | Science Translational Medicine
7 days ago
A smart bandage enables efficient wound fluid capture and multiplexed biosensing of...
A high-resolution screen identifies a preexisting beta-lactam that specifically treats Lyme disease in mice | Science Translational Medicine
7 days ago
Piperacillin, an FDA-approved beta-lactam, is effective at killing the Lyme disease–causing agent...