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Last updated 3 days ago
Vaccinology in the artificial intelligence era | Science Translational Medicine
3 days ago
Artificial intelligence has the potential to revolutionize the entire vaccinology pipeline, but...
Condensation of cellular prion protein promotes renal fibrosis through the TBK1-IRF3 signaling axis | Science Translational Medicine
3 days ago
PrPC activates TBK1-IRF3 signaling to worsen renal fibrosis in mice, highlighting amlexanox...
Liver-targeted allergen immunotherapy rapidly and safely induces antigen-specific tolerance to treat allergic airway disease in mice | Science Translational Medicine
3 days ago
Liver-targeted synthetically mannosylated allergens induce allergen-specific tolerance in preclinical models of allergic...
Expansion of a bacterial operon during cancer treatment ameliorates fluoropyrimidine toxicity | Science Translational Medicine
3 days ago
Gut bacterial enzymes can be used to predict and prevent anticancer drug...
Pentatricopeptide repeat protein targeting CUG repeat RNA ameliorates RNA toxicity in a myotonic dystrophy type 1 mouse model | Science Translational Medicine
3 days ago
AAV9-mediated systemic delivery of a protein that targets CUG repeat RNA ameliorates...
Preclinical development of anti-CD21 chimeric antigen receptor T cells to treat T cell acute lymphoblastic leukemia | Science Translational Medicine
3 days ago
Fratricide-resistant anti-CD21 CAR-T cells are effective in preclinical models of T cell...
Erratum for the Research Article “Targeting GOLPH3L improves glioblastoma radiotherapy by regulating STING-NLRP3–mediated tumor immune microenvironment reprogramming” by S. Sun et al. | Science Translational Medicine
3 days ago
After publication of the Research Article “Targeting GOLPH3L improves glioblastoma radiotherapy by...
The mRNA export pathway licenses viral mimicry response and antitumor immunity by actively exporting nuclear retroelement transcripts | Science Translational Medicine
10 days ago
Tumor cells hijack the mRNA export pathway to obstruct nuclear export of...
The response to anti–PD-1 and anti–LAG-3 checkpoint blockade is associated with regulatory T cell reprogramming | Science Translational Medicine
10 days ago
Treg instability drives anti–PD-1 + anti–LAG-3 treatment efficacy and is associated with...
Collagen V regulates renal function after kidney injury and can be pharmacologically targeted to enhance kidney repair in mice | Science Translational Medicine
10 days ago
Collagen V regulates renal fibrosis and can be targeted with precision medicine...
Spatial genomics: Mapping the landscape of fibrosis | Science Translational Medicine
10 days ago
Spatial genomics unlocks insights into the pathobiology of multiorgan fibrosis across time...
Rapid tuberculosis diagnosis from respiratory or blood samples by a low cost, portable lab-in-tube assay | Science Translational Medicine
10 days ago
A low complexity, portable lab-in-tube tuberculosis assay for resource-limited areas analyzes blood...