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Last updated about 12 hours ago
Oligodendroglial precursor cells modulate immune response and early demyelination in a murine model of multiple sclerosis | Science Translational Medicine
about 12 hours ago
The chemokine receptor 5 antagonist maraviroc attenuates EAE pathogenesis in mouse models...
Clinically compliant enrichment of human pluripotent stem cell–derived islets | Science Translational Medicine
about 12 hours ago
Stem cell–derived islets can be enriched by density gradient separation.
Mavoglurant reduces cocaine use in patients with cocaine use disorder in a phase 2 clinical trial | Science Translational Medicine
about 12 hours ago
In a randomized, placebo-controlled clinical trial, mavoglurant reduced cocaine and alcohol use...
Ebola virus vaccination elicits Ebola virus–specific immune responses without substantial cross-reactivity to other filoviruses | Science Translational Medicine
about 12 hours ago
The Ad26/MVA Ebola virus vaccine elicited coordinated antibody and T cell responses...
Self-regulating gene therapy ameliorates phenotypes and overcomes gene dosage sensitivity in a mouse model of Rett syndrome | Science Translational Medicine
about 12 hours ago
A gene therapy construct for Rett syndrome includes a self-regulating, miRNA-based feed-forward...
Path to a cure for debilitating pregnancy sickness | Science Translational Medicine
about 12 hours ago
Identification of GDF15 as a cause of severe nausea and vomiting during...
Human iPSC–derived nephron progenitor cells treat acute kidney injury and chronic kidney disease in mouse models | Science Translational Medicine
about 12 hours ago
Expanded human iPSC–derived nephron progenitor cells secrete renoprotective factors that have therapeutic...
Identification and characterization of human retinal stem cells capable of retinal regeneration | Science Translational Medicine
8 days ago
Human neural retinal stem-like cells (hNRSCs) found in fetal retinas and organoids...
Tick feeding or vaccination with tick antigens elicits immunity to the Ixodes scapularis exoproteome in guinea pigs and humans | Science Translational Medicine
8 days ago
Comprehensive profiling of Ixodes scapularis antigens reveals that tick bites induce antivector...
Variant screening of PYY3–36 leads to potent long-acting PYY analogs with superior Y2 receptor selectivity | Science Translational Medicine
8 days ago
A Y2 receptor–selective and long-acting PYY derivative improves weight loss and glucose...
TRIM15 drives chondrocyte senescence and osteoarthritis progression | Science Translational Medicine
8 days ago
TRIM15 promotes chondrocyte senescence and osteoarthritis progression by mediating K48-linked ubiquitination and...
Anopheles mosquito survival and pharmacokinetic modeling show the mosquitocidal activity of nitisinone | Science Translational Medicine
8 days ago
Nitisinone reduces survival of the malaria-transmitting mosquito Anopheles gambiae by blocking tyrosine...