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Last updated about 23 hours ago
Deep humoral profiling coupled to interpretable machine learning unveils diagnostic markers and pathophysiology of schistosomiasis | Science Translational Medicine
about 23 hours ago
Antibody profiling and machine learning provide insight into the underlying pathophysiology of...
Intratumoral radiation dose heterogeneity augments antitumor immunity in mice and primes responses to checkpoint blockade | Science Translational Medicine
about 23 hours ago
Radiation dose heterogeneity promotes systemic antitumor immunity through induction of diverse immune...
Preschool-age children maintain a distinct memory CD4+ T cell and memory B cell response after SARS-CoV-2 infection | Science Translational Medicine
about 23 hours ago
Preschool-age children mount a different adaptive immune response to SARS-CoV-2 than adults.
Perfusion imaging metrics after acute traumatic spinal cord injury are associated with injury severity in rats and humans | Science Translational Medicine
about 23 hours ago
Ultrasound perfusion metrics are correlated with acute spinal cord injury severity in...
A deep intronic splice–altering AIRE variant causes APECED syndrome through antisense oligonucleotide-targetable pseudoexon inclusion | Science Translational Medicine
about 23 hours ago
An extrathymic AIRE expression system uncovered a deep intronic AIRE variant that...
ARGX-119 is an agonist antibody for human MuSK that reverses disease relapse in a mouse model of congenital myasthenic syndrome | Science Translational Medicine
about 23 hours ago
ARGX-119 is a first-in-class MuSK agonist monoclonal antibody in clinical development for...
Targeted partial reprogramming of age-associated cell states improves markers of health in mouse models of aging | Science Translational Medicine
8 days ago
Reprogramming aged cells through targeted overexpression of Oct4, Sox2, and Klf4 leads...
A spatially resolved single-cell lung atlas integrated with clinical and blood signatures distinguishes COVID-19 disease trajectories | Science Translational Medicine
8 days ago
A single-cell lung atlas integrated with clinical and blood signatures can predict...
Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models | Science Translational Medicine
8 days ago
Reversal agents for rocuronium were identified from rocuronium-specific antibody repertoires.
Erratum for the Research Article “Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled tissue-specific expression of an mRNA encoding IL-12p70” by B. Brook et al. | Science Translational Medicine
8 days ago
In the Research Article “Adjuvantation of a SARS-CoV-2 mRNA vaccine with controlled...
HIF-2α drives hepatic Kupffer cell death and proinflammatory recruited macrophage activation in nonalcoholic steatohepatitis | Science Translational Medicine
8 days ago
HIF-2α regulates macrophage subtype–specific growth and function to enhance the development of...
BATF is a major driver of NK cell epigenetic reprogramming and dysfunction in AML | Science Translational Medicine
8 days ago
BATF deletion prevents epigenetic rewiring and enhances the antitumor activity of NK...