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Last updated 1 day ago
Global organelle profiling reveals subcellular localization and remodeling at proteome scale
1 day ago
Organelle proteomics defines the cellular landscape of protein localization and highlights the...
Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease
1 day ago
A metagenome-informed metaproteomics approach unravels the interplay between the host, gut microbiome...
An atlas of transcription initiation reveals regulatory principles of gene and transposable element expression in early mammalian development
1 day ago
Mapping transcription start sites across five mammalian species before, during, and after...
Hyperacute rejection-engineered oncolytic virus for interventional clinical trial in refractory cancer patients
1 day ago
A Newcastle disease virus engineered to enhance anti-tumor immune responses provided a...
Integration of 168,000 samples reveals global patterns of the human gut microbiome
1 day ago
The Human Microbiome Compendium is a unified database of publicly available human...
Rhodoquinone carries electrons in the mammalian electron transport chain
1 day ago
Valeros et al. identify rhodoquinone (RQ), an electron carrier present in mammalian...
Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes
1 day ago
Lymph node swelling is a well-known symptom of infection. A shift in...
Squeeze pumping of lipids and insecticides by ABCH transporter
1 day ago
High-resolution cryo-EM structures and biochemical data reveal the dynamic process by which...
Plasmodesmata act as unconventional membrane contact sites regulating intercellular molecular exchange in plants
1 day ago
Plant intercellular communication is regulated via tubular ER-PM membrane contact through PI4P...
Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation
1 day ago
Beyond its role as RNA m6A writer, METTL3-METTL14 can mediate 5mC deposition...
Designed mosaic nanoparticles enhance cross-reactive immune responses in mice
1 day ago
Computational methods were used to design mosaic nanoparticle vaccines displaying receptor-binding domains...
A biophysical basis for the spreading behavior and limited diffusion of Xist
1 day ago
HNRNPK condensates change material properties when interacting with Xist RNA, thereby facilitating...