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Last updated 5 days ago
Method of moments framework for differential expression analysis of single-cell RNA sequencing data
5 days ago
Memento implements a statistical model and a fast resampling procedure to estimate...
Microbial transformation of dietary xenobiotics shapes gut microbiome composition
5 days ago
Individuals can exhibit significant interpersonal variation in diet-microbiome interaction. This report uncovers...
Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket
5 days ago
Morstein et al. demonstrate the feasibility of inhibiting GTPases beyond K-Ras, including...
Emergence of community behaviors in the gut microbiota upon drug treatment
5 days ago
A comparison of the effects of pharmaceuticals on different gut bacterial species...
Retraction notice to: hnRNP K: An HDM2 Target and Transcriptional Coactivator of p53 in Response to DNA Damage
5 days ago
(Cell 123, 1065–1078; December 16, 2005)
Metformin decelerates aging clock in male monkeys
5 days ago
Prolonged metformin treatment diminishes the multidimensional biological age and alleviates neuronal aging...
Light-induced remodeling of phytochrome B enables signal transduction by phytochrome-interacting factor
5 days ago
Cryo-EM structures of Arabidopsis photoactivated phyB and its constitutively active phyBY276H mutant...
A two-front nutrient supply environment fuels small intestinal physiology through differential regulation of nutrient absorption and host defense
5 days ago
Spatiotemporal mapping of the environment of the mouse small intestine enables the...
In vivo DNA replication dynamics unveil aging-dependent replication stress
5 days ago
In vivo DNA replication dynamics in regenerating mouse livers unveil aging-dependent decline...
CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease
5 days ago
Examination of CSF proteins in mutation carriers and non-carriers for autosomal dominant...
A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson’s disease
5 days ago
A neuronal circuit originating in the brainstem pons and medulla strongly induces...
Fine-grained descending control of steering in walking Drosophila
5 days ago
The brain's role in generating purposeful locomotion depends on a set of...