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Last updated 2 days ago

Global organelle profiling reveals subcellular localization and remodeling at proteome scale

2 days ago

Organelle proteomics defines the cellular landscape of protein localization and highlights the...

Metagenome-informed metaproteomics of the human gut microbiome, host, and dietary exposome uncovers signatures of health and inflammatory bowel disease

2 days ago

A metagenome-informed metaproteomics approach unravels the interplay between the host, gut microbiome...

An atlas of transcription initiation reveals regulatory principles of gene and transposable element expression in early mammalian development

2 days ago

Mapping transcription start sites across five mammalian species before, during, and after...

Hyperacute rejection-engineered oncolytic virus for interventional clinical trial in refractory cancer patients

2 days ago

A Newcastle disease virus engineered to enhance anti-tumor immune responses provided a...

Integration of 168,000 samples reveals global patterns of the human gut microbiome

2 days ago

The Human Microbiome Compendium is a unified database of publicly available human...

Rhodoquinone carries electrons in the mammalian electron transport chain

2 days ago

Valeros et al. identify rhodoquinone (RQ), an electron carrier present in mammalian...

Inflammation switches the chemoattractant requirements for naive lymphocyte entry into lymph nodes

2 days ago

Lymph node swelling is a well-known symptom of infection. A shift in...

Squeeze pumping of lipids and insecticides by ABCH transporter

2 days ago

High-resolution cryo-EM structures and biochemical data reveal the dynamic process by which...

Plasmodesmata act as unconventional membrane contact sites regulating intercellular molecular exchange in plants

2 days ago

Plant intercellular communication is regulated via tubular ER-PM membrane contact through PI4P...

Fine-tuning of gene expression through the Mettl3-Mettl14-Dnmt1 axis controls ESC differentiation

2 days ago

Beyond its role as RNA m6A writer, METTL3-METTL14 can mediate 5mC deposition...

Designed mosaic nanoparticles enhance cross-reactive immune responses in mice

2 days ago

Computational methods were used to design mosaic nanoparticle vaccines displaying receptor-binding domains...

A biophysical basis for the spreading behavior and limited diffusion of Xist

2 days ago

HNRNPK condensates change material properties when interacting with Xist RNA, thereby facilitating...