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Last updated 3 days ago
scMultiSim: simulation of single-cell multi-omics and spatial data guided by gene regulatory networks and cell–cell interactions
3 days ago
Nature Methods, Published online: 17 April 2025; doi:10.1038/s41592-025-02651-0scMultiSim is a comprehensive single-cell...
Imaging 3D cell cultures with optical microscopy
3 days ago
Nature Methods, Published online: 17 April 2025; doi:10.1038/s41592-025-02647-wThis Review discusses current 2D...
An exceptionally photostable mScarlet3 mutant
3 days ago
Nature Methods, Published online: 17 April 2025; doi:10.1038/s41592-025-02675-6mScarlet3-H is a highly stable...
A highly stable monomeric red fluorescent protein for advanced microscopy
3 days ago
Nature Methods, Published online: 17 April 2025; doi:10.1038/s41592-025-02676-5The red fluorescent protein mScarlet3-H...
Error-corrected flow-based sequencing at whole-genome scale and its application to circulating cell-free DNA profiling
9 days ago
Nature Methods, Published online: 11 April 2025; doi:10.1038/s41592-025-02648-9This work integrates duplex sequencing...
Perturb-tracing enables high-content screening of multi-scale 3D genome regulators
10 days ago
Nature Methods, Published online: 10 April 2025; doi:10.1038/s41592-025-02652-zThis work presents Perturb-tracing, integrating...
PTM-Mamba: a PTM-aware protein language model with bidirectional gated Mamba blocks
10 days ago
Nature Methods, Published online: 10 April 2025; doi:10.1038/s41592-025-02656-9PTM-Mamba is a post-translational modification-aware...
Computer vision for primate behavior analysis in the wild
10 days ago
Nature Methods, Published online: 10 April 2025; doi:10.1038/s41592-025-02653-yIn this Perspective, Vogg et...
Pooled CRISPR screening with optical sequencing reveals regulators of 3D chromatin organization
10 days ago
Nature Methods, Published online: 10 April 2025; doi:10.1038/s41592-025-02633-2The Perturb-Tracing approach represents a...
CAVE: Connectome Annotation Versioning Engine
11 days ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-024-02426-zThe Connectome Annotation Versioning Engine...
CRISPR–Csm guided RNA imaging
11 days ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-025-02672-9CRISPR RNA-targeting tools enable the...
Efficient and robust search of microbial genomes via phylogenetic compression
11 days ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-025-02625-2Phylogenetic compression achieves performant and...